The invention discloses a medical waste treatment device, comprising a compression block, a working cavity is arranged in the compression block, a compression mechanism is arranged in the working cavity, and the compression mechanism includes a compression mechanism fixed on the rear end wall of the working cavity The upper side of the compression mechanism is provided with a shearing mechanism, the shearing mechanism includes a cross bar, the rear end wall of the working chamber is provided with a positioning groove, the right side of the shearing mechanism is provided with a transmission mechanism, and the transmission mechanism Including the motor fixed on the rear end wall of the working chamber, the device is easy to operate, put the medical waste into the device, the small medical waste will directly fall into the compression chamber, and the disposable infusion tube etc. The medical waste will be blocked, and then the device will cut off the disposable infusion tube, and the cut off disposable infusion tube will fall into the compression chamber. At this time, the cut off disposable infusion tube can be compressed better achieve compression.