The invention provides a DC-DC (Direct Current to Direct Current) converter with high efficiency, high gain and low voltage and current stresses. In the DC-DC converter, a direct-current power supply, a switch tube, a first diode, a second diode, a fourth diode, a fifth diode, a first inductor, a third inductor, a first capacitor, a third capacitor and a fourth capacitor construct an input-grade Boost converter; the first capacitor, the switch tube, a third diode, a sixth diode, a seven diode, an eighth diode, a ninth diode, a second inductor, a fourth inductor, a fifth capacitor, a sixth capacitor, a seventh capacitor, an eighth capacitor, a second capacitor and a load construct an output grade Boost converter. The input Boost converter and the output Boost converter are connected to the second inductor and the fourth inductor to serve as resonant inductors, so that the zero current turning-on of the switch tube is realized; meanwhile, the zero current turning-off of each diode is realized. The gain of the converter is 6 / (1-D)2, and the voltage stress of the switch tube is one third that of the output voltage.