41results about How to "Improve the ability to resist external pathogen infection" patented technology

The invention relates to the field of protein, in particular to a bioactive peptide SKVLPVPEKAVPYPQ as well as a preparation method and an application thereof. An amino acid sequence of the bioactive peptide SKVLPVPEKAVPYPQ is Ser-Lys-Val-Leu-Pro-Val-Pro-Glu-Lys-Ala-Val-Pro-Tyr-Pro-Gln. An in-vitro anti-oxidation experiment and an in-vitro immunity function promoting experiment prove that the bioactive peptide SKVLPVPEKAVPYPQ has better anti-oxidation biological activity and immunity regulation function, on one hand, the bioactive peptide SKVLPVPEKAVPYPQ has better anti-oxidation activity, can clear free radicals in an organism and improves life quality; on the other hand, by the aid of the bioactive peptide SKVLPVPEKAVPYPQ, in-vitro proliferation capacity of lymphocytes and macrophages can be enhanced, the phagocytosis capacity of the macrophages for neutral red is improved, the organism's capacity of resisting outside pathogen infection is improved, morbidity of the organism is reduced, and therefore, the bioactive peptide SKVLPVPEKAVPYPQ has quite great significance in development of food, healthcare products and drugs with an immune regulation function and an anti-oxidation function.

The invention relates to the field of protein, in particular to a bioactive polypeptide PMIGVNQELAY, and a preparation method and application thereof. The amino acid sequence of the bioactive polypeptide PMIGVNQELAY is Pro-Met-Ile-Gly-Val-Asn-Gln-Glu-Leu-Ala-Tyr. In vitro antioxidant experiments and in vitro immune function promoting experiments prove that the polypeptide PMIGVNQELAY has better antioxidant biological activity and immune modulating functions; on one hand, good antioxidant activity is realized; free radicals in the body can be cleared away; the life quality is improved; on the other hand, the bioactive polypeptide PMIGVNQELAY can enhance the in vitro multiplication capacity of lymphocytes and macrophages; the capability of the macrophages for devouring toluylene red is promoted; the capability of the body for resisting the external pathogen infection is improved; the body morbidity is reduced; very important significance is realized for developing food, health care products and medicines with the immune modulating function and the antioxidant function.

The invention relates to the field of protein, and in particular to a bioactive polypeptide TIASGEPT, and a preparation method and application thereof. An amino acid sequence of the bioactive polypeptide TIASGEPT is Thr-Ile-Ala-Ser-Gly-Glu-Pro-Thr. An in-vitro antioxidant experiment and an in-vitro immunological function promoting experiment verify that the bioactive polypeptide TIASGEPT has better antioxidant biological activity and a better immune modulating function; on one hand, the bioactive polypeptide TIASGEPT has better antioxidant activity and is capable of removing free radicals in a body and increasing the quality of life; on the other hand, the bioactive polypeptide TIASGEPT is capable of enhancing in-vitro proliferation ability of lymphocytes and macrophages, promoting the increment of nitric oxide induction amount of the macrophages, increasing the ability of defending external pathogen infection by the body and reducing the morbidity of the body, and has a very important significance in developing food, healthcare products and drugs, which have an immune modulating function and an antioxidant function.

The invention relates to the field of a protein and particularly relates to a milk-derived bioactive polypeptide QEPVL with in-vitro antioxidant activity and body immunity promoting activity, wherein an amino acid sequence of the bioactive polypeptide QEPVL is Gln-Glu-Pro-Val-Leu. Through an in-vitro antioxidant test and an in-vitro immunity promoting test, the polypeptide QEPVL is proved to have relatively good antioxidant biological activity and immunity improving function; on one hand, free radicals in the body can be removed to reduce the harm on the human body caused by the free radicals; on the other hand, according to the bioactive polypeptide QEPVL, the immunity of the body can be further enhanced and the multiplication capacity of lymphocytes in vitro can be promoted, thereby improving the ability of the body to resist infections of external pathogens and reducing the incidence rate of the body without causing immunological rejections. The bioactive polypeptide QEPVL has great significance for the development of milk products, healthcare products and medicines with the antioxidant function and the immunity enhancement.

The invention relates to the technical field of health-care food, in particular to a chlorella pyrenoidosa polypeptide weight-increasing relieving composition as well as a preparation method of the composition. In the composition, chlorella pyrenoidosa polypeptide serves as one of main functional components and are compounded with soybean polypeptide, corn polypeptide, lentinan, hericium Erinaceuspolysauharides, wheat oligopeptides powder, green tea polyphenol extracts and medlar concentrated juice, the effect of the components can be exerted completely, and the components are mutually synergistic, so that the composition provided by the invention can promote fat metabolism and reduce storage subcutaneous fat, has the significant effect of reliving weight increment and can enhance immunity. The composition provided by the invention consists of the components according to a certain proportioning, has rich and balanced nutrition, is delicious, healthy and safe, and is suitable for people of any age to eat; in addition, the composition provided by the invention has the effects of tonifying spleen and tonifying stomach.

The invention relates to an albumen powder for improving organism immunity and a preparation method of the albumen powder. The albumen powder comprises the following components in percentage by weight: 75-89% of soy isolate protein, 10-20% of condensed whey protein powder, 0.5-1% of an antitackiness agent and 0.5-4% of lecithin. The preparation method comprises steps of pre-sieving, weighing and distributing, and mixing to obtain the product. The albumen powder provided by the invention is comprehensive in nutrition, safe and reliable to eat without dependence; and after being eaten often, the albumen powder is capable of improving organism immunity, increasing the ability of the organism for resisting the external pathogen infection and improving the life quality, can be used as a modern health food and has a wide market future.

The invention relates to the field of protein, in particular to a bioactive peptide AAGGYDVEKNNSRIKLGLK as well as a preparation method and application thereof, and the amino acid sequence of the bioactive peptide AAGGYDVEKNNSRIKLGLK is Ala-Ala-Gly-Gly-Tyr-Asp-Val-Glu-Lys-Asn-Asn-Ser-Arg-Ile-Lys-Leu-Gly-Leu-Lys. An in-vitro immunoregulation function experiment proves that the bioactive peptide AAGGYDVEKNNSRIKLGLK has a very good immunoregulation function. The bioactive peptide AAGGYDVEKNNSRIKLGLK disclosed by the invention can promote macrophages to secrete cytokines and phagocytize neutral red, improve the effect of the macrophages in a normal macrophage resting state, improve the capability of resisting external pathogen infection of organisms, reduce the morbidity of the organisms and improve the quality of life; the polypeptide has very important significance in developing food, health care products and medicines with immunoregulation functions.

The present invention proposes an oral thick paste capable of increasing white blood cell content. The oral thick paste is prepared from the following raw materials in parts by weight: 10-20 parts ofCarboxymethylpachymaran, 12-17 parts of colostrum basic protein, 5-10 parts of wheat oligopeptide, 35-40 parts of mulberry, 5-10 parts of longan aril, 10-20 parts of coix seeds, 20-25 parts of solomonseal rhizomes, 10-20 parts of Chinese yams, 20-25 parts of jujubes and 15-20 parts of honey. The oral thick paste of the invention has the functions of enhancing the immunity of the body, increasing the content of white blood cells in the blood and improving the body's hypoxia tolerance, and has a definite therapeutic effect of treating diseases such as low immune function and leukopenia. The rawmaterial source of the invention is wide, the preparation method is simple, and the prepared oral thick paste has a good immune enhancement effect, can promote white blood cell content, stimulate lymphocyte proliferation and reduce the morbidity of the body, and has broad application prospects.

The invention discloses a dietetic therapy formula for resisting to inflammation, improving cardiovascular and cerebrovascular diseases and regulating blood sugar and in-vivo qi and blood. The dietetic therapy formula adopts the raw material selection and components as follows: 76.8-96 kg of barley grass powder, 0.8-1 kg of wheat low-poly titanium, 1.6-2 kg of chlorella pyrenoidosa and 0.8-1 kg of chitosan oligosaccharide. The dietetic therapy formula for resisting to inflammation, improving cardiovascular and cerebrovascular diseases and regulating blood sugar and in-vivo qi and blood, which is provided by the invention, is prepared by stirring and mixing the quantitative barley grass powder, wheat low-poly titanium, chlorella pyrenoidosa and chitosan oligosaccharide, and vitamin C, beta-carotene, an antioxidant enzyme, total glutamic acid, CGF and other substances contained in the dietetic therapy formula take a synergistic effect, the pH value of blood can be balanced, the body recovery of post-operation crowds is accelerated, the immunity of organisms is improved, the hematopoietic function is enhanced, qi and blood of a human body are effectively regulated, the blood sugar can be reduced, blood fat can be reduced, hypertension can be reduced, nutritional ingredients of the body can be supplemented, the cell regeneration working capacity is promoted, and the dietetic therapy formula is suitable for rehabilitation and conditioning of people with cardiovascular and cerebrovascular diseases.

The invention relates to the field of protein, in particular to a bioactive peptide SGSAAWDDSAGGAGGQGLRVTAL as well as a preparation method and application thereof, and the amino acid sequence of thebioactive peptide SGSAAWDDSAGGAGGQGLRVTAL is Ser-Gly-Ser-Ala-Ala-Trp-Asp-Asp-Ser-Ala-Gly-Gly-Ala-Gly-Gly-Gln-Gly-Leu-Arg-Val-Thr-Ala-Leu. An in-vitro immunoregulation function experiment shows that the bioactive peptide SGSAAWDDSAGGAGGQGLRVTAL has a relatively good immunoregulation function. The invention further discloses a preparation method of the bioactive peptide SGSAAWDDSAGGAGGQGLRVTAL. Thebioactive peptide SGSAAWDDSAGGAGGQGLRVTAL can promote macrophage activation, release cytokines and improve the external pathogen infection resistance of an organism, has a remarkable promoting effecton the neutral red phagocytosis capacity of in-vitro macrophages under the condition that inflammation occurs, can reduce the incidence rate of the organism, improves the life quality, and has very important significance in developing food, health care products and medicines with immunoregulation functions.

Provided is a milk-derived biologically active polypeptide having an amino acid sequence of QEPVL, which has in-vitro antioxidation activity and promotes immune activity of human body. In-vitro antioxidation and in-vitro immunity promotion experiments prove that the peptide has good biological antioxidation activity, and has the function of enhancing immunity.

The invention relates to the field of protein, in particular to bioactive peptide ASEPPVLDVKRPFLC (Adenosine Sulfate-Polyvinylpyrrolidone-Vitamin K Receptor Fluorescent Cell) as well as a preparationmethod and application thereof. The amino acid sequence of the bioactive peptide ASEPPVLDVKRPFLC is Ala-Ser-Glu-Pro-Pro-Val-Leu-Asp-Val-Lys-Arg-Pro-Phe-Leu-Cys. An in-vitro immune function regulationexperiment proves that the bioactive peptide ASEPPVLDVKRPFLC has a relatively good immune regulation function. The bioactive peptide ASEPPVLDVKRPFLC can effectively inhibit inflammation caused by oxidation of a body, promote macrophages to secrete cytokines, improve the effect of the macrophages in a resting state of normal macrophages, improve the capacity of the body for resisting external pathogen infection, reduce the morbidity of the body and improve the life quality, and has very important significance in developing food, health care products and medicines with immunoregulation functions.

The present invention relates to the field of proteins, in particular to a bioactive peptide KQSLPPGLAVKDLK and its preparation method and application. The amino acid sequence of the bioactive peptide KQSLPPGLAVKDLK is Lys‑Gln‑Ser‑Leu‑Pro‑Pro‑Pro‑Gly‑Leu‑Ala‑Val‑Lys ‑Asp‑Leu‑Lys. The in vitro immune function regulation experiment proved that the biologically active peptide KQSLPPGLAVKDLK has a good immune regulation function. The biologically active peptide KQSLPPGLAVKDLK of the present invention has the ability to enhance the in vitro proliferation of macrophages and lymphocytes, improve the ability of the body to resist external pathogen infection, reduce the incidence of the body, improve the quality of life, and is useful for the development of food and health products with immune regulation functions. and drugs are of great importance.

The invention relates to the field of proteins, in particular to bioactive polypeptide VAVVKKGSNFQ as well as a preparation method and application thereof. An amino acid sequence of the bioactive polypeptide VAVVKKGSNFQ is Val-Ala-Val-Val-Lys-Lys-Gly-Ser-Asn-Phe-Gln. In-vitro antioxidant experiments and in-vitro immune function promotion experiments prove that the polypeptide VAVVKKGSNFQ has better antioxidant biological activity and an immune regulation function; on the one hand, the polypeptide VAVVKKGSNFQ has the better antioxidant activity, thus being capable of removing free radicals in a human body and further improving the quality of life; on the other hand, the bioactive polypeptide VAVVKKGSNFQ can enhance the in vitro proliferative capacity of lymphocytes and macrophages and promote the increment of nitrogen monoxide induction amount of the macrophages, thus improving the external pathogen infection resistance of the organism and reducing the morbidity of the organism; therefore, the bioactive polypeptide VAVVKKGSNFQ has a very important significance for developing food, health care products and medicines which have the immune regulation function and the antioxidant function.

Provided is a milk-derived biologically active polypeptide having an amino acid sequence of DELQ, which has in-vitro antioxidation activity and promotes immune activity of human body. In-vitro antioxidation and in-vitro immunity promotion experiments prove that the peptide has good biological antioxidation activity, and has the function of enhancing cellular immunity.

The invention relates to the field of proteins, in particular to a biologically active peptide RLAFIAHPKLG and a preparation method and application thereof. The amino acid sequence of the biologically active peptide RAFIAHPKLG is Arg-Leu-Ala-Phe-Ile-Ala-His-Pro-Lys-Leu-Gly . Through in vitro immunomodulatory function experiments, it was found that the biologically active peptide RLAFIAHPKLG has a good immunomodulatory function. The bioactive peptide RLAFIAHPKLG of the present invention has the ability to enhance the in vitro proliferation ability of lymphocytes, can promote macrophages to secrete cytokines, improve the body's ability to resist infection by external pathogens, reduce the body morbidity rate, improve the quality of life, and has immunomodulatory effects on development Functional foods, health products and medicines are of great significance.

The present invention relates to the field of proteins, in particular to a bioactive peptide LECVEPNCRSKR and its preparation method and application. The amino acid sequence of the bioactive peptide LECVEPNCRSKR is Leu-Glu-Cys-Val-Glu-Pro-Asn-Cys-Arg-Ser-Lys ‑Arg. Through the in vitro immune function regulation experiments, it was verified that the biologically active peptide LECVEPNCRSKR has a good immune regulation function. The biologically active peptide LECVEPNCRSKR of the present invention has the ability to increase the induction of macrophage nitric oxide under a certain concentration, can effectively inhibit the inflammation caused by oxidation in the body, inhibit the overexpression of inflammatory factors, and improve the body's resistance to external pathogens The ability to infect, reduce the morbidity of the body, and improve the quality of life are of great significance to the development of foods, health products and medicines with immune regulation functions.

Provided is a milk-derived biologically active polypeptide having an amino acid sequence of LPLP, which has in-vitro antioxidation activity and enhances immunity of human body. The polypeptide has good biological antioxidation activity, and has the function of enhancing immunity of cells and human body.

The invention provides a nutritious food with a function of boosting immunity and a preparation method of the nutritious food. The nutritious food disclosed by the invention comprises the following components in percentage by weight: 5%-10% of wheat oligopeptides powder, 0.08%-0.12% of zinc gluconate, 0.03%-0.05% of vitamin B2, 12%-16% of lentinus edodes powder, 10%-14% of whole milk powder, 8%-12% of isolated soy protein powder, 7%-11% of oat powder, and 40%-60% of an auxiliary material. The nutritious food provided by the invention is reasonable in component matching, is capable of providing various nutritional ingredients such as sufficient protein, amino acids, mineral substances, vitamins for a human body, simultaneously has the efficacies of improving the immunity of the organisms and reducing the disease risk of the human body, is especially suitable for being used as a breakfast assist or substitute food; and in addition, the nutritious food disclosed by the invention is good in taste and flavor, convenient to eat, easy to absorb by the human body, and wide in market prospect, and meets the consumption needs of modern society people.

The invention discloses bioactive peptides with APN inhibitory effect, the amino acid sequences of which are respectively Cys-Asn-Arg, Cys-Asp-Arg and Gly-Glu-Phe. The invention proves that the bioactive peptides Cys-Asn-Arg, Cys-Asp-Arg and Gly-Glu-Phe have APN inhibitory effect and anti-tumor potential activity through structure screening and activity measurement. At the same time, the bioactive peptides Cys‑Asn‑Arg, Cys‑Asp‑Arg and Gly‑Glu‑Phe exist stably under in vivo digestion conditions, can be fully absorbed and utilized by the body to exert their biological activity, and have anti-tumor functions for development Food, health products and medicines are of great significance.

The invention relates to the field of protein, in particular to a bioactive peptide KQSLPPGLAVKDLK as well as a preparation method and application thereof, and the amino acid sequence of the bioactivepeptide KQSLPPGLAVKDLK is Lys-Gln-Ser-Leu-Pro-Pro-Gly-Leu-Ala-Val-Lys-Asp-Leu-Lys. In-vitro immune function regulation experiments prove that the bioactive peptide KQSLPPGLAVKDLK has a very good immune regulation function. The bioactive peptide KQSLPPGLAVKDLK disclosed by the invention has the effects of enhancing the in-vitro proliferation capability of macrophages and lymphocytes, improving thecapability of resisting external pathogen infection of an organism, reducing the morbidity of the organism and improving the quality of life, and has very important significance for developing foods,health care products and medicines with an immunoregulation function.

The present invention relates to the field of protein, in particular to a biologically active peptide having an amino acid structure VVRKPLNKEGKKP and its preparation method and application. The amino acid sequence of the biologically active peptide VVRKPLNKEGKKP is shown in SEQ ID NO: 1, and the amino acid sequence of the biologically active peptide VVRKPLNKEGKKPR is shown in SEQ ID NO: 2 shown. In vitro immunoregulatory function experiments have proved that the bioactive peptides VVRKPLNKEGKKP and VVRKPLNKEGKKPR have good immune regulatory functions. The VVRKPLNKEGKKP and VVRKPLNKEGKKPR of the present invention have the ability to promote the increase in the induction of macrophage nitric oxide under certain concentration conditions, thereby improving the body's ability to resist external pathogen infection, reducing the incidence of the body, and at the same time promoting the proliferation of macrophages in vitro and exerting their full potential. The immune function of the body is of great significance to the development of food, health products and medicines with immune regulation function.

The present invention relates to the field of proteins, in particular to a bioactive peptide IAHPKLGKRIR and its preparation method and application. The amino acid sequence of the bioactive peptide IAHPKLGKRIR is Ile‑Ala‑His‑Pro‑Lys‑Leu‑Gly‑Lys‑Arg‑Ile‑Arg . In vitro immune function regulation experiments proved that the biologically active peptide IAHPKLGKRIR has a good immune regulation function. The biologically active peptide IAHPKLGKRIR of the present invention can promote the proliferation ability of lymphocytes in vitro, improve the immunity of the human body, and at the same time have a significant promotion effect on the ability of macrophages to phagocytize neutral red in vitro, improve the body's ability to resist external pathogen infection, reduce the body's It is of great significance to develop food, health care products and medicines with immune regulation function and improve the quality of life.

The invention relates to the field of protein, in particular to bioactive peptides VPYPQRDMPI and a preparation method and application thereof. An amino acid sequence of the bioactive peptides VPYPQRDMPI is Val-Pro-Tyr-Pro-Gln-Arg-Asp-Met-Pro-Ile. By means of the in-vitro anti-inflammation activity experiment and in-vivo anti-ageing experiment, it is verified that the peptides VPYPQRDMPI has the good anti-inflammation activity and anti-ageing activity, on one hand, the bioactive peptides VPYPQRDMPI can promote macrophage to secrete cell factors, increasing of the induced volume of macrophage nitric oxide is promoted, the external pathogen infection resisting capacity of organism is improved, and the incidence of the organism is lowered; on the other hand, the vitality of in-vivo peroxidasesystem resistance can be increased, the exogenous stimulus resisting function of the organism is enhanced, and then the probability of organism ageing, senility and sickness is lowered, and great significance on developing foods, health-care products and medicine which have the anti-inflammation and anti-ageing functions is achieved.

The invention relates to the field of protein, in particular to a bioactive peptide with an amino acid structure VVRKPLNKEGKKP as well as a preparation method and application of the bioactive peptide. The amino acid sequence of the bioactive peptide VVRKPLNKEGKKP is shown as SEQ ID NO: 1, and the amino acid sequence of the bioactive peptide VVRKPLNKEGKKPR is shown as SEQ ID NO: 2. An in-vitro immune regulation function experiment proves that the bioactive peptides VVRKPLNKEGKKP and VVRKPLNKEGKKPR have a very good immune regulation function. The VVRKPLNKEGKKP and the VVRKPLNKEGKKPR disclosed by the invention have the capability of promoting the increase of nitric oxide induction amount of macrophages under a certain concentration condition, so that the capability of resisting external pathogen infection of a body is improved, the morbidity of the body is reduced, meanwhile, the proliferation of in-vitro macrophages is promoted, the immune function of the body is exerted, and the bioactive peptide has very important significance for developing food, health care products and medicines with immune regulation functions.