30results about How to "Guaranteed effectiveness and safety" patented technology

To more accurately control insertion of penetrating instruments (e.g., trocars, needles, or the like) into a body cavity, organ, or potential space, an accelerometer is coupled to the penetrating instrument. The accelerometer may by employed to measure or detect the sudden lack of resistance which occurs when the penetrating instrument penetrates to a predetermined depth (e.g., through the abdominal cavity, vein, or outer bone) in a more accurate and reliable way instead of practitioners' subjective feeling. An acceleration sensor (i.e., accelerometer) coupled to the penetrating instrument (e.g., trocar or the like) may transform the physical variable ‘resistance change’ into an electronic signal that is then processed in an electronic circuit, and finally triggers an audible / visible alarm and / or feeds an actuating mechanism to control movement of the penetrating instrument.

An invention relating to therapeutic pharmacological agents and methods to chemically induce intracellular hyperthermia and / or free radicals for the diagnosis and treatment of infections, malignancy and other medical conditions. The invention relates to a process and composition for the diagnosis or killing of cancer cells and inactivation of susceptible bacterial, parasitic, fungal, and viral pathogens by chemically generating heat, and / or free radicals and / or hyperthermia-inducible immunogenic determinants by using mitochondrial uncoupling agents, especially 2,4 dinitrophenol and, their conjugates, either alone or in combination with other drugs, hormones, cytokines and radiation.

A non-permeable pipe connector structure, the design of which effectively prevents external material (such as vapor and miscellaneous substances, etc.) intrusion. To obstruct the intrusion of external matter into the pipe connector, a ball bearing holder is disposed at the pipe connector, enabling even greater ball bearing durability and, furthermore, free rotation. A protective flange is disposed as the bottom surface of the ball bearing holder such that when the coupling nipple and the connector base are fastened together, the protective flange effectively blocks external matter, thereby precluding entry to avert subsequent damage to the bearings. Furthermore, a rubber sealing ring sleeved onto the annular groove prevents vaporous or acid and alkaline substance intrusion into the bearings, and has safe defensive effectiveness.

An invention relating to therapeutic pharmacological agents and methods to chemically induce intracellular hyperthermia and / or free radicals for the diagnosis and treatment of infections, malignancy and other medical conditions. The invention relates to a process and composition for the diagnosis or killing of cancer cells and inactivation of susceptible bacterial, parasitic, fungal, and viral pathogens by chemically generating heat, and / or free radicals and / or hyperthermia-inducible immunogenic determinants by using mitochondrial uncoupling agents, especially 2,4 dinitrophenol and, their conjugates, either alone or in combination with other drugs, hormones, cytokines and radiation.

A medication dispenser comprises a body with an opening, an advancing device, a reader, an output device and a processor connected to the advancing device, the reader and the output device. The body is closable and lockable and is arranged to receive a medication container comprising multiple individual sealed medication chambers, each medication chamber including a data tag relating to the medication chamber. The opening in the body is for a medication chamber and the advancing device is arranged to advance a medication chamber through the opening. The reader is arranged to read a data tag on a medication chamber and the processor is arranged to control the advancing device and the output device, according to a data tag on a medication chamber.

A medicine bottle with a solid silica flaky drying agent is disclosed. The solid silica flaky drying agent is wrapped in a filter paper and packed inside a bubble cap on which a number of holes are provided for moisture absorption. The bubble cap containing the solid silica flake drying agent can be attached to the cap of the medicine bottle via a baseplate behind a circular locking notch for preventing the solid silica flake drying agent from falling off the cap, or placed at the bottom of the medicine bottle which has a circular locking notch to prevent the solid silica flake drying agent from falling out of the medicine bottle.

The present invention provides a rapid safety cord concentrator, and more particularly a cord concentrator, having application in window curtains, which binds the free ends of pull cords, and enables the external force produced at the outset of the pull cords being operated by accident to be transmitted linearly into the cord concentrator. Accordingly, the binding stationary state gripping force of the cord concentrator on the pull cords is easily broke apart, thus causing the cord concentrator to instantly lose its gripping force on the pull cords and rapidly separating therefrom, thereby immediately releasing entangled limbs or torso from the pull cords.

A window curtain pull cord concentrator safety device of the present invention provides a concentrator device which enables the gathering together of the free ends of a plurality of pull cords of a window curtain set, and enables complete transmission of a pulling force in an emergency. And basically comprises a drag cup, an inner bottom of a concave cavity of which is provided with a through hole enabling a wire hoop body coupled to a pulling member to penetrate therethrough. The wire hoop body is located in the interior of the drag cup, and displacement of an inner loop side of the wire hoop body relative to the drag cup is used to determine whether the free ends of the pull cords are radially restrained, thereby enabling complete relay transmission of the pulling force. In an emergency, the pull cords are rapidly released, thereby achieving instantaneous prompt safety effectiveness.

The present invention relates to a method of activating a fingerprint identification process of a smart card according to a given condition and a device thereof. The present invention uses a contactless smart card as a carrier of the fingerprint identification technology and incorporates user identification during use of the card to make the transaction or access process more secure and efficient. The invention provides the steps of how to determine whether the fingerprint identification process of the smart card should be activated to verify the validation of the user before the transaction according to the comparison result between the transaction amount and the preset conditional value.

A medicine bottle with a solid silica flaky drying agent is disclosed. The solid silica flaky drying agent is wrapped in a filter paper and packed inside a bubble cap on which a number of holes are provided for moisture absorption. The bubble cap containing the solid silica flake drying agent can be attached to the cap of the medicine bottle via a baseplate behind a circular locking notch for preventing the solid silica flake drying agent from falling off the cap, or placed at the bottom of the medicine bottle which has a circular locking notch to prevent the solid silica flake drying agent from falling out of the medicine bottle.

A non-permeable pipe connector structure, the design of which effectively prevents external material (such as vapor and miscellaneous substances, etc.) intrusion. To obstruct the intrusion of external matter into the pipe connector, a ball bearing holder is disposed at the pipe connector, enabling even greater ball bearing durability and, furthermore, free rotation. A protective flange is disposed as the bottom surface of the ball bearing holder such that when the coupling nipple and the connector base are fastened together, the protective flange effectively blocks external matter, thereby precluding entry to avert subsequent damage to the bearings. Furthermore, a rubber sealing ring sleeved onto the annular groove prevents vaporous or acid and alkaline substance intrusion into the bearings, and has safe defensive effectiveness.

The disclosure is premised on the realization that despite the apparent convenience, safety and effectiveness possible by use of a less-lethal weapon incorporated into the foregrip of a two-handed weapon, no major police department, government agency, or military unit deploys such a system. This deficiency can be remedied by the disclosed device, which comprises a less-lethal weapon system that employs industry-standard components, and is effective and easy to use. The disclosed invention mounts a standard-size incapacitant canister in the handgrip portion of a foregrip. The foregrip is secured to the firearm by a standard rail system, and uses standard trigger and safety configurations. The canister magazine allows for efficient loading and reloading of the incapacitant, and the canister mounting angle allows for effective use. Further, some embodiments of the invention may include an accessory mounting area in which a tactical flashlight or laser may be mounted.

For providing a recording / reproducing apparatus, for recoding and reproducing a digital signal onto first and second recording media 200 and 300, in particular, being simple in the controlling method when conducting data copying between those recording media, being difference in the control formats thereof, comprising: a memory 104 for storing therein the digital signal, temporality; an input / output portion 101, through which a control signal and the digital signal for use of recording and reproducing are inputted and outputted; a controller 102 for performing two (2) kinds of controlling, being different from each other, with respect to said first and second recording media, upon basis of a one (1) kind of control signal inputted at said input / output portion; and an arbiter 103 for arbitrating and processing the digital signal in a time-sharing manner among said first recoding medium, said second recording medium and said memory, wherein the signal recorded in the first recording medium 200 recorded onto the second recording medium 300 through the memory 104, thereby making a copy of data between the recording media differing from, but without passing through the input / output portion 101.

Compact perineal warming device for personal non invasive portable and stationary use to prevent and alleviate prostate discomfort, to use without any kind of assistance at home, the workplace or while driving, wearing it concealed under or exposed over the clothes, comprising a small warming unit integrated by an encased ceramic electrical resistance, which is attached to a special strap-on supporting harness or to a special adjustable split cushion to keep it at the user's perineum in order to radiate concentrated infrared heat focused towards the prostate, being preset to locally increase the temperature within safe limits to prevent and relieve the pain and discomfort associated with some common disorders of the prostate which is easily operated and powered at safe low voltage from a portable power bank or from any available power source through conventional power adapters.

Herbal compositions and their use in the prevention and / or treatment of hepatitis are provided The herbal compositions comprise an extract of flowers, leaves, and roots from the plant genera Cordia, Annona, and Curcuma, respectively, wherein the specific species are Cordia lutea, Annona muricata and Curcuma longa.

For providing a recording / reproducing apparatus, for recoding and reproducing a digital signal onto first and second recording media 200 and 300, in particular, being simple in the controlling method when conducting data copying between those recording media, being difference in the control formats thereof, comprising: a memory 104 for storing therein the digital signal, temporality; an input / output portion 101, through which a control signal and the digital signal for use of recording and reproducing are inputted and outputted; a controller 102 for performing two (2) kinds of controlling, being different from each other, with respect to said first and second recording media, upon basis of a one (1) kind of control signal inputted at said input / output portion; and an arbiter 103 for arbitrating and processing the digital signal in a time-sharing manner among said first recoding medium, said second recording medium and said memory, wherein the signal recorded in the first recording medium 200 recorded onto the second recording medium 300 through the memory 104, thereby making a copy of data between the recording media differing from, but without passing through the input / output portion 101.

The present invention relates to a method of activating a fingerprint identification process of a smart card according to a given condition and a device thereof. The present invention uses a contactless smart card as a carrier of the fingerprint identification technology and incorporates user identification during use of the card to make the transaction or access process more secure and efficient. The invention provides the steps of how to determine whether the fingerprint identification process of the smart card should be activated to verify the validation of the user before the transaction according to the comparison result between the transaction amount and the preset conditional value.

The disclosure is premised on the realization that despite the apparent convenience, safety and effectiveness possible by use of a less-lethal weapon incorporated into the foregrip of a two-handed weapon, no major police department, government agency, or military unit deploys such a system. This deficiency can be remedied by the disclosed device, which comprises a less-lethal weapon system that employs industry-standard components, and is effective and easy to use. The disclosed invention mounts a standard-size incapacitant canister in the handgrip portion of a foregrip. The foregrip is secured to the firearm by a standard rail system, and uses standard trigger and safety configurations. The canister magazine allows for efficient loading and reloading of the incapacitant, and the canister mounting angle allows for effective use. Further, some embodiments of the invention may include an accessory mounting area in which a tactical flashlight or laser may be mounted.

A window curtain pull cord concentrator safety device of the present invention provides a concentrator device which enables the gathering together of the free ends of a plurality of pull cords of a window curtain set, and enables complete transmission of a pulling force in an emergency. And basically comprises a drag cup, an inner bottom of a concave cavity of which is provided with a through hole enabling a wire hoop body coupled to a pulling member to penetrate therethrough. The wire hoop body is located in the interior of the drag cup, and displacement of an inner loop side of the wire hoop body relative to the drag cup is used to determine whether the free ends of the pull cords are radially restrained, thereby enabling complete relay transmission of the pulling force. In an emergency, the pull cords are rapidly released, thereby achieving instantaneous prompt safety effectiveness.

The present invention provides a snake venom thrombin marker peptide of Agkistrodon Halys Pallas and an application of the snake venom thrombin-like enzyme in identifying species of Hemocoagulase for Injection. The application includes the following steps of: dissolving a to-be-detected sample and a reference substance of the marker peptide respectively to prepare a test solution and a reference solution, and conducting alkylation reduction on the test solution and the reference solution with dithiothreitol and iodoacetamide; after diluting products with an ammonium bicarbonate solution, adding enzyme for hydrolysis; and after enzymolysis is finished, conducting centrifugation at a high speed, and injecting a supernatan into a liquid chromatography-mass spectrometer for analysis. This method is simple, convenient and rapid, is strong in specificity, fills the gap in identifying the source of species of the snake venom thrombin-like enzyme of Agkistrodon Halys Pallas and improves the quality control level.

A synthetic peptide sp2 has the amino acid sequence shown in SEQ ID No. 1. sp2 has obvious anti-tumor growth activity on xenograft tumours such as subcutaneous human pancreatic cancer, human cervical cancer, and human ovarian cancer in nude mice, with a dose-effect and time-effect relation; and has the effect of delaying metastasis and prolonging the survival time of nude mouse having in situ transplantation of human pancreatic cancer and lung adenocarcinoma. After the animals were given intravenous injection of sp2 at a dose of 2000 mg / kgBW, no toxicity reaction and death were observed. The applications of sp2 also include: (1) preventing and / or treating of tumor; (2) inhibiting proliferation and / or growth and / or invasion of tumor cells; (3) enhancing the anti-tumor immune response; (4) inducing tumor cell differentiation; (5) preparing anti-tumor drugs; (6) inhibiting tumor telomerase activity; and (7) regulating the tumor cell cycle.

An after-sales system platform provides business modeling functions to enhance commercial values as a measure for deriving business direction, and includes multiple front-end data providing units, a cloud platform and a client service server. The front-end data providing units provide relevant information. The cloud platform has multiple category databases and an information screening unit and categorizes the relevant information and stores the relevant information in the respective category databases. The client service server acquires categorized information through the information screening unit by request. The categorized information can be used for a multi-oriented business model including service policy making, business assessment, and research and development management. The system platform employs innovative concepts of vehicles and remotely piloted vehicles and is implemented on the basis of an on-board diagnostic II.

The invention discloses a special device for brewing gastrointestinal filling type ultrasonic contrast agent, which includes a stirrer, a brewing container, and a cooling container. The brewing container includes a brewing cup, and the cooling container is sleeved on the brewing On the cup, the brewing cup is provided with a cup cover, the cup cover is fixedly connected with the brewing cup, the cup cover is designed with a stirring hole and a temperature monitoring hole, and the agitator passes through the stirring hole Placed in the brewing cup, the upper part of the cooling container is provided with a water injection port, the lower part of the cooling container is provided with a drain port, and the wall of the cooling container is also fixedly provided with a cup handle. A temperature monitor is fixedly installed, and the temperature monitor is placed into the brewing cup through the temperature monitoring hole. The invention can accurately grasp the temperature of each stage, guarantee the effectiveness and safety of the solution in the configuration process to the greatest extent, and ensure the image forming quality.

The present application relates to a system and a method for effectively screening and assessing agents for tumor immunotherapy, which includes assessment for the effects of target cells, non-target cells, and tumor infiltration. The system and method of the present application can be used to comprehensively and systematically assess the effectiveness and safety of the agent against tumor immune cells.

The invention discloses a special brewing apparatus for gastrointestinal filling type contrast agents. The special brewing apparatus comprises a stirrer, a brewing container and a cooling container. The brewing container comprises a brewing cup, the cooling container sleeves the brewing cup, a cup lid is arranged on the brewing cup and is fixedly connected with the brewing cup, a stirring hole and a temperature monitoring hole are formed in the cup lid, the stirrer is arranged in the brewing cup via the stirring hole, a water filling opening is formed in the upper portion of the cooling container, a drain outlet is formed in the lower portion of the cooling container, a cup handle is further fixedly arranged on a wall of the cooling container, and a temperature monitor is fixedly mounted on the cup handle and is arranged in the brewing cup via the temperature monitoring hole. The special brewing apparatus has the advantages that the temperatures can be accurately controlled at various stages, accordingly, the effectiveness and the safety of liquor can be guaranteed to the greatest extent in preparation procedures, and the imaging quality can be guaranteed.

The present invention relates to the technical field of medicine, in particular to a conjugate of dezocine and polyethylene glycol and a pharmaceutical composition thereof. The conjugate of dezocine and water-soluble oligomer provided by the present invention has better pharmacokinetic properties and a high drug absorption degree, may reduce the side effects of the drug, and achieve a smaller administration dosage and a more diverse mode of administration, such as oral administration, in clinic. Compared with dezocine, the conjugate of the present invention has a stronger analgesic effect and a longer analgesic duration, may reduce the frequency of drug administration, improve patient compliance, and has advantages in effectiveness and safety of the drug, as well as drug tolerance, etc.