75results about How to "Broad protection" patented technology

An interceptor device for protecting a platform against an incoming threat is provided. The interceptor device comprises a housing and a countermeasure device. At least one detonating charge is capable of deploying the countermeasure device. A controller device housed by the housing is capable of directing the detonating charge(s) to deploy the countermeasure device at least partially radially outward of the housing, corresponding to the threat trajectory. A sensor device is in communication with the controller device, and comprises a range-finding apparatus including one of a LADAR, a RADAR, and a LIDAR device, capable of sensing the threat and / or a range thereof, at least partially radially outward of the housing, and notifying the controller device if the threat is sensed, to cause the controller device to direct the detonating charge(s) to deploy the countermeasure device to impact the threat in the intercept zone. Associated systems, and methods are also provided.

The present invention generally provides methods and compositions for eliciting an immune response against Neisseria spp. bacteria in a subject, particularly against a Neisseria meningitidis serogroup B strain.check for moving around

An interceptor device for protecting a platform against an incoming threat is provided. The interceptor device comprises a housing and a countermeasure device. At least one detonating charge is capable of deploying the countermeasure device. A controller device housed by the housing is capable of directing the detonating charge(s) to deploy the countermeasure device at least partially radially outward of the housing, corresponding to the threat trajectory. A sensor device is in communication with the controller device, and comprises a range-finding apparatus including one of a LADAR, a RADAR, and a LIDAR device, capable of sensing the threat and / or a range thereof, at least partially radially outward of the housing, and notifying the controller device if the threat is sensed, to cause the controller device to direct the detonating charge(s) to deploy the countermeasure device to impact the threat in the intercept zone. Associated systems, and methods are also provided.

Sunscreen compositions contain the active ingredients avobenzone, zinc oxide and phenylbenzimidazole sulfonic acid. The phenylbenzimidazole sulfonic acid protects avobenzone against photodegradation.

An interceptor device adapted to protect a platform associated therewith against an incoming threat having a trajectory by intercepting the threat in an intercept zone is provided. Such an interceptor device comprises a housing defining an axis and a countermeasure device operably engaged with the housing. At least one detonating charge is housed by the housing and is operably engaged with the countermeasure device. A controller device is in communication with the at least one detonating charge, wherein the controller device is housed by the housing and is configured to direct the at least one detonating charge to deploy the countermeasure device at least partially radially outward with respect to the axis of the housing and in correspondence with the trajectory of the threat to thereby cause the countermeasure to impact the threat in the intercept zone. Associated apparatuses, systems, and methods are also provided.

A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and / or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammalian Borrelia infections.

An all natural topically applied broad spectrum photo-filtering composition for both styling of hair and protecting hair and scalp from ultraviolet radiation is comprised of natural oils, vitamins and amino acids having UV absorption properties which in combination with at least one inorganic particulate selected from the group consisting of titanium dioxide arid zinc oxide afford broad spectrum photo protection of both hair and scalp across the UV and IRA spectrum. Combining the above with bees wax, glycerin, gelatin and wafer, produces an emulsified gel suitable for styling hair while simultaneously protecting the hair and scalp from damaging UV and IR rays.

Methods and formulations for treating animal ectoparasites, effective against parasites such as fleas and ticks are provided. The methods comprise topically co-administering a non-mobile insect growth regulator, a mobile insect growth regulator, and an adulticide to the animal. Parasiticidal formulations for treating animal ectoparasites are also provided, which can be safe to use and avoids the many common deleterious side effects of conventional topical formulations. The topical formulations comprise a combination of two insect growth regulators and an additional insecticide. The topical formulation can be packaged together or packaged so that active components are stored separately prior to administering the topical insecticide formulation to the animal.

A botanical antioxidant composition includes a botanical antioxidant extract blend including a first antioxidant botanical extract including at least one hydroxycinnamic acid, and at least one additional antioxidant botanical extracts including at least one antioxidant selected from the group consisting of vitamins, stilbenoids, curcumininoids, tannins, flavones, flavonols, flavan-3-ols, flavanones, anthocyanidins, anthocyanins, isoflavones, flavanonols, proanthocyanidins, dihydroxybenzoic acids, and pyridine alkaloids.

A topical formulation having significant parasiticidal activity effective against endoparasites and / or ectoparasites such as heartworms, mites, fleas, ticks, flies is provided, which can be safe to use and avoids the many common deleterious side effects of conventional topical formulations. The topical formulations comprise a combination of a macrocyclic lactone, a neo-nicotinoid and optionally, an insect growth regulator. The topical formulation can be packaged together or packaged so that the macrocyclic lactone and the neo-nicotinoid are stored separately prior to administering the topical insecticide formulation to the animal.

Peptide-based anti-influenza formulations against influenza A and B are disclosed. The peptides are derived from influenza-based epitopes. The formulations are based on peptide mixtures which may be formulated so that variability is present at particular residues. The formulations can be used to prepare vaccines for preventing influenza in human, avian, murine or equine animals.

The invention discloses a reinforcing method utilizing waterlogged wood relics of nanocellulose. The reinforcing method comprises the following steps of: mixing nanocellulose with a filling agent to obtain a reinforcing agent; and performing dehydrating and desalination on the waterlogged wood relics, and adding the waterlogged wood relics into the reinforcing agent to soak, and performing drying for reinforcing. The waterlogged wood relics obtained by treatment of the reinforcing method are bright in color, are good in stability, do not easily separate out salts, and are especially free of secondary acid degradation. The reinforcing method disclosed by the invention can be used for effectively clearing and protecting the reinforcing method, the dried and reinforced wood is stabilized to a pH neutral state, acid corrosion and salt separation are effectively restrained, and mechanical strength of highly rotten wood is greatly reinforced.

A class of UVA- and UVB-absorbing esters has been derived by modifying hydroxy triglycerides and other acyltriglycerides with any of a variety of cinnamic acids. The esterification reactions are preferably conducted at elevated temperatures without a catalyst. The resultant agents have the advantage of being synthesized from natural materials, while providing a value-added use for the oil. They are readily formulated into standard UV-absorbing daily-wear cosmetic, hair and skin care, and sunscreen formulations.

A topical formulation having significant parasiticidal activity effective against endoparasites and / or ectoparasites such as heartworms, mites, fleas, ticks, flies is provided, which can be safe to use and avoids the many common deleterious side effects of conventional topical formulations. The topical formulations comprise a combination of a macrocyclic lactone, a neo-nicotinoid and optionally, an insect growth regulator. The topical formulation can be packaged together or packaged so that the macrocyclic lactone and the neo-nicotinoid are stored separately prior to administering the topical insecticide formulation to the animal.

This invention relates, e.g., to a virus-like particle (VLP) composition assembled from a chimeric polypeptide comprising a papilloma virus (e.g., human papillomavirus, or HPV) L1 major capsid protein, into which is inserted a surface-displayed peptide comprising a neutralizing epitope of a papillomavirus L2 protein. Vaccine compositions comprising the VLP are described, as well as methods for inducing an immune response (e.g., vaccinating) a subject against papilloma virus, using the VLP, and kits comprising the VLP, for carrying out a method of the invention.

A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and / or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammalian Borrelia infections.

A botanical antioxidant composition includes a botanical antioxidant extract blend including a first antioxidant botanical extract including at least one hydroxycinnamic acid, and at least one additional antioxidant botanical extracts including at least one antioxidant selected from the group consisting of vitamins, stilbenoids, curcumininoids, tannins, flavones, flavonols, flavan-3-ols, flavanones, anthocyanidins, anthocyanins, isoflavones, flavanonols, proanthocyanidins, dihydroxybenzoic acids, and pyridine alkaloids.

The present invention relates to an agricultural composition comprising sulphur in the range from 20% to 80% of the total composition, a chloronicotinyl compound in the range from 0.7% to 25% of the total composition, a pyrethroid compound in the range from 0.75% to 10% of the total composition and at least one agrochemically acceptable excipient

Methods for providing broad spectrum photo protection to skin using antioxidants that provide UVA protection to skin are described. The methods include topically applying a cosmetic composition comprising: (a) at least one antioxidant having an Oxygen Radical Absorbance Capacity (ORAC) of at least 10,000 μmol TE / g and a Hydroxyl Radical Absorbance Capacity (HORAC) of at least 2,600 μmol GAE / g; (b) at least one organic UV filter; and (c) a cosmetically acceptable carrier; wherein the cosmetic composition provides an increase in UVAPPD PF of at least 30% relative to an otherwise identical cosmetic composition without the antioxidant(s) of (a). The disclosure also relates to the cosmetic compositions useful in the described methods.

Methods for producing quadrivalent meningococcal meningitis polysaccharide and conjugate vaccines for serotypes A, C, Y and W-135 disclosed. Neisseria meningitidis fastidious medium was designed to maximize the yield of capsular polysaccharides and generate minimal cellular biomass and endotoxin in a short duration of fermentation. The crude polysaccharides are isolated, purified, and mechanically depolymerized by sonication. These purified polysaccharides were found in human clinical trials to be safe and immunogenic against meningococcal disease caused by N. meningitidis A, C, Y and W-135 serogroups in sub-Saharan Africa. In the preferred embodiment, the polysaccharides are conjugated to carrier proteins of diphtheria or tetanus toxiod to an average molecular size of 5100 to 9900 Daltons and provide broad spectrum protection to humans of all ages. Accelerated polysaccharide production and the efficacy of the resulting vaccine are demonstrated.

The present invention provides a means to broadly protect the military and the public from injury from biological warfare weapons, particularly infective agents such as anthrax. Beta (1,3)-glucans, particularly whole glucan particles, PGG-Glucan, and microparticulate glucan, provide general immune enhancement, thereby increasing the body's ability to defend against a wide variety of biological threats. Beta (1,3)-glucans have been shown to increase the resistance to infection by anthrax and other infectious organisms when administered before and after infection. The anti-infective mechanism of β(1,3)-glucan appears to involve stimulation of the innate immune system through increased cytokine release and CR3 receptor activation. Beta (1,3)-glucan is pharmaceutically stable, relatively compact, and can also be used without significant side effects. Beta (1,3)-glucan can also enhance the effectiveness of other medical countermeasures such as antibiotics, vaccines, and immune antibodies.

This invention relates, e.g., to a virus-like particle (VLP) composition assembled from a chimeric polypeptide comprising a papilloma virus (e.g., human papillomavirus, or HPV) L1 major capsid protein, into which is inserted a surface-displayed peptide comprising a neutralizing epitope of a papillomavirus L2 protein. Vaccine compositions comprising the VLP are described, as well as methods for inducing an immune response (e.g., vaccinating) a subject against papilloma virus, using the VLP, and kits comprising the VLP, for carrying out a method of the invention.

The invention provides a method for changing water wave propagation direction by arranging an underwater obstacle. The method comprises the steps that 1, the bottom face size of the underwater obstacle is determined according to the horizontal span of a target water area; 2, the specific shape of the underwater obstacle is determined, wherein the number and distribution positions of data points onan underwater obstacle bus are set, and the coordinate values, corresponding to the water depth, of the radius are calculated according to a transformation equation; data calculated according to thetransformation equation is substituted into an underwater obstacle height calculation formula, and then the coordinate values of the data points on the corresponding underwater obstacle bus can be obtained; a bus curve is drawn according to the coordinate values of the data points, the bus curve is rotated by 360 degrees around the central axis to generate a cone, and then the specific shape of the underwater obstacle is obtained; 3, the underwater obstacle is arranged, wherein the underwater obstacle is manufactured based on the data in the step 2, then the underwater obstacle is placed at the water bottom of the upstream of the target water area, the water surface wave propagation direction passing through the underwater obstacle is deflected, and the target water area is protected against the influence of waves.

A class of UVA- and UVB-absorbing esters has been derived from milkweed oil by modification with a variety of cinnamic acids. These agents have the advantage of being synthesized from natural materials, while providing a value-added use for the oil. They are readily formulated into standard UV-absorbing daily-wear cosmetic, hair and skin care, and sunscreen formulations.

Methods and formulations for treating animal ectoparasites, effective against parasites such as fleas and ticks are provided. The methods comprise topically co-administering a non-mobile insect growth regulator and a mobile insect growth regulator to the animal. Parasiticidal formulations for treating animal ectoparasites are also provided, which can be safe to use and avoid the many common deleterious side effects of conventional topical formulations. The topical formulations comprise a combination of two insect growth regulators, a non-mobile insect growth regulator and a mobile insect growth regulator. The topical formulation can be packaged with the two insect growth regulators together or packaged to prevent mixing of the two insect growth regulators prior to administering the topical insecticide formulation to the animal.

The invention discloses a reinforcing method utilizing waterlogged wood relics of nanocellulose. The reinforcing method comprises the following steps of: mixing nanocellulose with a filling agent to obtain a reinforcing agent; and performing dehydrating and desalination on the waterlogged wood relics, and adding the waterlogged wood relics into the reinforcing agent to soak, and performing drying for reinforcing. The waterlogged wood relics obtained by treatment of the reinforcing method are bright in color, are good in stability, do not easily separate out salts, and are especially free of secondary acid degradation. The reinforcing method disclosed by the invention can be used for effectively clearing and protecting the reinforcing method, the dried and reinforced wood is stabilized to a pH neutral state, acid corrosion and salt separation are effectively restrained, and mechanical strength of highly rotten wood is greatly reinforced.

The present invention relates to an pesticidal composition comprising an effective amount of a sulphur; an effective amount of at least one insecticide selected from the group consisting of cartap fipronil, pirimicarb, buprofezine, thiachloprid, acetamiprid, clothianidin, diafenthiuron, novaluron, flubendiamide, spirotetramat, thiamethoxam, imidacloprid or salts thereof, and at least one agrochemically acceptable excipient.

The invention discloses a multi-epitope antigen for piglet diarrhea, a vaccine, a preparation method of the antigen and applications of the antigen and the vaccine. A multi-epitope antigen fusion (MEFA) technology is utilized, and adhesin subunits FaeG and FedF of dominant expression fimbriae F4 and fimbriae F18 of ETEC strains causing piglet diarrhea are used as skeletons respectively. According to the invention, FaeG-FedF-FasA-FanC-Fim41a MEFA proteins of five fimbriae adhesin expressed by the ETEC strains capable of targeting to cause diarrhea of weaned piglets are constructed, so as to be used as effective and broad-spectrum vaccines for preventing diarrhea of newborn piglets and weaned piglets caused by ETEC infection.