54 results about "Graft procedure" patented technology

A coronary artery bypass graft procedure is performed through one or more openings made in the patient to create a point of entry to the thoracic cavity. A vein measurement device measures the distance between the proximal and distal anastomotic sites for each graft. A proximal anastomosis tool splits to release a graft vessel after deploying an anastomosis device at the proximal anastomosis site. The tool may be articulated. An integrated stabilizer stabilizes one or more tools relative to the surface of the beating heart at a distal anastomotic site. A distal anastomotic tool may be provided as part of the integrated stabilizer, and connects one end of the graft vessel to a target vessel. An epicardial dissector may be provided as part of the integrated stabilizer, and dissects the epicardium from the target vessel at a distal anastomotic site, as needed.

Devices and methods are disclosed for stabilizing tissue within a patient's body during a surgical operation to provide a relatively motionless surgical field, such as during a coronary artery bypass graft procedure. The devices include tissue stabilizers which engage and provide stabilization to a targeted area of tissue and further have the ability to engage and manipulate some portion of tissue within or adjacent the targeted area to improve the surgical presentation of that portion of tissue. The tissue stabilizer typically has one or more stabilizer feet which have a first foot portion configured to provide stabilization to the targeted tissue and a second foot portion moveable relative to the first foot portion for manipulating a portion of tissue to improve the surgical presentation.

A method is disclosed for preparing a soft tissue site, and augmenting the soft tissue site, such as the breast(s) of a subject through use of devices that exert a distractive force on the breast(s) and grafting of autologous fat tissue such as domes with sealing rims for surrounding each of the breasts and a regulated pump. The method for preparing the soft tissue site, and enhancing fat graft results, entails application of the distracting force to the targeted soft tissue site for several weeks prior to the graft procedure. A related aspect of the invention includes following the preparation steps by transfer of fat from other areas of the subject to the subject's breast(s), and then reapplication of the distractive force to the breast(s) that received the autologous fat graft. Alternatively, fat from genetically related sources may be used, and the fat may be further processed prior to injection. Substantial breast augmentation, high rates of graft survival and negligible graft necrosis (data demonstrating 80% survival and only 20% necrosis is presented) or calcification result from the practice of these methods.

A method is disclosed for preparing a soft tissue site, and augmenting the soft tissue site, such as the breast(s), scar, depression, or other defect, of a subject through use of devices that exert a distractive force on the breast(s) and grafting of autologous fat tissue such as domes with sealing rims for surrounding each of the soft tissue site and a regulated pump. The method for preparing the soft tissue site, and enhancing fat graft results, entails application of the distracting force to the targeted soft tissue site at least intermittently for some period of time and preferably several weeks prior to the graft procedure. A related aspect of the invention includes following the preparation steps by transfer of fat from other areas of the subject to the subject's soft tissue site, and then reapplication of the distractive force to the soft tissue site that received the autologous fat graft. Alternatively, fat from genetically related sources may be used, and the fat may be further processed prior to injection. Substantial soft tissue augmentation, high rates of graft survival and negligible graft necrosis (data demonstrating 80% survival and only 20% necrosis is presented) or calcification result from the practice of these methods.

A method and apparatus are provided for regulating pressure applied during a medical procedure, including an inelastic housing enclosing an inner volume, a housing having a first and second end; an aperture in the housing, the aperture for coupling to an element for applying a pressure during a medical procedure, the element having an inner volume communicated with the inner volume of the housing; and a pressure-operated valve coupled to the housing for providing access to the inner volume of the housing when pressure in the housing is above a threshold, whereby the valve releases pressure from within the inner volume of the housing. The method and apparatus are particularly useful in preparation of conduits such as veins and arteries during grafting procedures.

A method of treating or preventing a disease or condition in a subject that was previously treated with at least one thienopyridine is described. The method includes administering to the subject an effective amount of at least one reversible, short-acting P2Yi2 inhibitor. The described method can be used for subjects diagnosed with symptoms such as stable or unstable angina, vascular ischemic events, atherosclerosis, acute coronary syndrome, as well as STEMi or N-STEMI. The described method can also be used for patients having previously received a stent, such as a bare metal stent or a drug-eluting stent, and the treatment or prevention of stent thrombosis. The method can be used prior to, during, or after an invasive procedure such as coronary artery bypass grafting, percutaneous coronary intervention, or other general surgical procedure.

Systems and methods for performing transcatheter coronary artery bypass grafting procedures are provided. The methods generally involve passing the graft from the aorta to the coronary artery through the pericardial space. The systems include poke-out wires, a coring device, and devices for forming anastomoses at the proximal and distal ends of a vascular graft.

A device and associated method for treating a skin graft donor site includes a sheet having dimensions to cover the skin graft donor site and an area of skin surrounding the skin graft donor site. An adhesive is provided that has properties of adhering to the skin and the sheet in a manner that forms a liquid impermeable boundary surrounding the skin graft donor site. A port is integrated with the sheet that enables a suction force to be applied therethrough to produce a negative pressure between the sheet and skin graft donor site to manage fluid produced by the skin graft donor site.

A method for performing a coronary artery bypass graft procedure on a patient to connect a bypass vessel to a target vessel includes the steps of creating an opening in the patient that communicates with the thoracic cavity of the patient; providing a bypass vessel having a lumen and at least one free end; passing the free end of the bypass vessel from the thoracic cavity through the opening to a position outside the body of the patient; attaching a connector to the free end of bypass vessel while the free end of the bypass vessel is outside the body of the patient; passing the free end of the bypass vessel from the position outside the body of the patient through the opening and into the thoracic cavity; and connecting the free end of the bypass vessel to a target vessel with the connector.

A device used to hold and position a blood vessel in the performance of a coronary artery bypass graft procedure includes a handle and an attachment head coupled to the handle. The attachment head has a collar adapted to substantially encircle the blood vessel and having a number of suction apertures. A vacuum port is adapted to be coupled to a vacuum source and communicates a suction to the suction apertures to hold the blood vessel.

Needle injectors and injector carriers for endothelial keratoplasty are provided. Needle injectors include first, second, and third portions each having a respective conduit therein. A first end of the second conduit is fluidly coupled to a second end of the first conduit, where the second conduit has a maximum diameter greater than a maximum diameter of the first conduit. A first end of the third conduit is configured to be fluidly coupled to a second end of the second conduit, where a second end of the third conduit is configured with a cutting surface for cutting and penetrating eye tissue. Injector carriers include a container, a cap configured to seal an opening of the container, and a coupling means configured to couple the needle injector to the cap and allow the needle injector to be disposed within the container.

A method and device are disclosed directed at harvesting of vessels, such as arteries and veins, especially as required in vessel grafting procedures. The device and method discloses a cannula-like device that provides, identification, capture, manipulation, hemostasis and cleavage of branch vessels from the harvested vessel without need for further devices. In certain preferred embodiments of the disclosed method and device, the disclosed harvesting device achieves branch vessel cleavage and hemostasis without the use of heat producing means such as cautery. In addition, certain embodiments utilize a clip / coil magazine technology so as to enable severance and hemostasis of multiple branch vessels without need for removal of the device from the surgical site. Further embodiments disclose the incorporation and use of irrigants containing CO2, as well as other agents capable of stimulate release of nitric oxide from vascular endothelium are applied to subject vessels so as to enhance the viability of vessels to be harvested as graft material.

Tissue-engineered vascular graft is designed to be used in cardiovascular surgeries, especially in coronary artery bypass grafting and peripheral vessels reconstruction procedures. Two-phase electrospinning technique was employed to fabricate a biodegradable polymer graft composed of the porous tubular scaffold supplemented by biologically active molecules, incorporated directly into the matrix walls in order to promote regeneration process of the patient's own vessel wall.

A method and system for performing anastomosis uses an anvil to control and support a tissue site during an anastomosis procedure involving tissue bonding techniques such as tissue welding and adhesive tissue bonding. The anvil is particularly useful for supporting a wall of a coronary artery during attachment of a graft vessel in a coronary artery bypass graft procedure. The anvil is inserted into a pressurized or unpressurized target vessel and is pulled against an inner wall of the target vessel causing tenting of the thin tissue of the vessel wall. A graft vessel is then advanced to the anastomosis site and an end of the graft vessel is positioned adjacent an exterior of the target vessel. When tissue welding is used, a graft vessel fixture is positioned over the tissue surfaces to be welded in order to clamp the graft and target vessel tissue together. The tissue contacting surfaces of the anvil and / or graft vessel fixture are provided with one or more energy applying surfaces. Energy in the form of RF power, laser energy or ultrasonic energy is then applied to the compressed graft and target vessel tissue to weld the vessels together. When adhesive bonding is used, the adhesive may be applied to mating surfaces of the graft and / or target vessels either before or after the vessels are brought into contact. After tissue bonding is complete, an incision is formed in the wall of the target vessel to allow blood flow between the target vessel and the graft vessel. The incision may be made with an electro-cautery cutting device.

The tunneling method for dental block grafting is surgical method for increasing the thickness of the soft tissue of the mouth prior to performing block grafting procedures for dental implants. The method includes cutting a pair of incisions in the mucosa. A tunnel is formed through the mucosa which extends between, and connects, the pair of incisions. The tunnel is then extended coronally to undermine tissue covering the recipient site. An acellular dermal matrix is then sutured to an exposed end of a dental implement pulled through the tunnel to position the acellular dermal matrix within the tunnel. The acellular dermal matrix is then positioned over the recipient site using a periosteal elevator, and the acellular dermal matrix is fixed coronally by suspension sutures. The pair of incisions are closed with interrupted sutures, and a block graft is fixed to the recipient site by a pair of titanium screws.

The disclosed apparatuses, methods, and systems provide for simulations of real-life bone graft procedures. One embodiment is a model that includes a base in the shape of at least a portion of a maxillary or mandibular dental arch, and includes a defect on its surface. The model also includes a multi-layer tissue model configured to overlay at least a portion of the base in a covering relationship with the defect and surrounding tissue. The multi-layer tissue model includes a gingival simulating layer, connective tissue simulating layer, and two adhesive layers. The first of the two adhesive layers connects the connective tissue simulating layer to the gingival simulating layer, and the second adhesive layer, affixed to the connective tissue simulating layer opposite the first layer, is configured to adhere the multi-layer tissue model to the base. The multi-layer tissue model also includes a removable backing covering the second adhesive layer.

An intravascular balloon occlusion device according to the invention is shown. The device is ideally suited for use in a coronary artery bypass graft procedure. The device includes a body having at least one selectively inflated balloon provided on the distal end thereof. Preferably, the body is a closed end body so that fluid can only flow from the proximal end of the body into the balloon. In use, the distal end of the body and the balloon are inserted into an aperture provided in the aorta. The balloon is inflated and then the device is retracted until the balloon seats against the incision or aperture in the aorta, thereby effectively sealing the aperture from the blood flow through the aorta, but not occluding blood flow through the body of the aorta itself. Next, the graft vessel is telescopically positioned on the occlusion device and mounted to the aorta. Once the vessel is secured thereto, the balloon is deflated and then the occlusion device is retracted from both the aorta and the graft vessel. Finally, the second end of the graft vessel is mounted to the appropriate coronary artery.

The present invention relates to tissue preservation for autologous and heterologous transplantation. In particular the present invention provides compositions and methods for the long-term storage of surgical conduits ex vivo for subsequent use in coronary artery bypass grafting.

The present disclosure relates generally to the assessment and treatment of vessels, including for percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). For example, some embodiments of the present disclosure are suited for identifying the available intervention technique(s) suitable to achieve a desired outcome selected or input by a user. For example, in some implementations a method comprises receiving pressure measurements obtained by one or more intravascular pressure-sensing instruments positioned within a vessel of a patient; receiving an input from a userregarding a desired pressure value for the vessel of the patient; identifying an available treatment option based on the received pressure measurements and the desired pressure value; and outputting,to a display device, a screen display including a visual representation of the available treatment option. Related devices and systems are also described.

Minimally invasive techniques utilized in bypass grafting are disclosed. For instance, a method of implanting an end portion of a graft in the body of a patient during a bypass grafting procedure includes the steps of (i) advancing a medical instrument within a circulatory system of said body, (ii) guiding a distal end of said medical instrument out of said circulatory system through an opening defined in said circulatory system after said medical instrument advancing step, (iii) advancing said end portion of said graft within said medical instrument after said guiding step, and (iv) securing said end portion of said graft to a blood vessel of said circulatory system after said end portion advancing step.

A bridge vessels-proximal anastomosis supporting device for coronary artery bypass grafting and a manufacturing method thereof. The bridge vessels-proximal anastomosis supporting device for the coronary artery bypass grafting comprises an arc-shaped body (1). An elliptical bottom edge (2) is arranged at the lower part of the arc-shaped body (1), a circular port (3) is arranged at the right side of the arc-shaped body (1), a notch is formed between the rightmost end of the bottom edge (2) and the lowermost end of the port, the diameter R of the circular port (3) is 4 mm, 5 mm, 6 mm, 7 mm or 8 mm, the major axis a of the elliptical bottom edge (2) is 13 mm, and the minor axis of the elliptical bottom edge (2) is the same as R. The body (1) is formed by weaving titanium-nickel alloy wires. The bottom edge (2) and the port (3) are provided with a supporting edge (5) made of a heavy metal material, and the supporting edge (5) is fixed with the wires (4) through medical non-absorbable sutures (6) in a wrapping manner. The device can support blood vessels of an anastomosis so as to prevent the blood vessels from generating collapse or deformation due to squeezing during an operation, thereby delaying occlusion of the anastomosis after the operation, and helping complete postoperative coronary angiography easily, accurately and quickly during re-examination.

A method and device are disclosed directed at harvesting of vessels, such as arteries and veins, especially as required in vessel grafting procedures. The device and method discloses a cannula-like device that provides, identification, capture, manipulation, hemostasis and cleavage of branch vessels from the harvested vessel without need for further devices. In certain preferred embodiments of the disclosed method and device, the disclosed harvesting device achieves branch vessel cleavage and hemostasis without the use of heat producing means such as cautery. In addition, certain embodiments utilize a clip / coil magazine technology so as to enable severance and hemostasis of multiple branch vessels without need for removal of the device from the surgical site. Further embodiments disclose the incorporation and use of irrigants containing CO2, as well as other agents capable of stimulate release of nitric oxide from vascular endothelium are applied to subject vessels so as to enhance the viability of vessels to be harvested as graft material.

Devices and methods are disclosed for stabilizing tissue within a patient's body during a surgical operation to provide a relatively motionless surgical field, such as during a coronary artery bypass graft procedure. The devices include tissue stabilizers which engage and provide stabilization to a targeted area of tissue and further have the ability to engage and manipulate some portion of tissue within or adjacent the targeted area to improve the surgical presentation of that portion of tissue. The tissue stabilizer typically has one or more stabilizer feet which have a first foot portion configured to provide stabilization to the targeted tissue and a second foot portion moveable relative to the first foot portion for manipulating a portion of tissue to improve the surgical presentation.

The tunneling method for dental block grafting is surgical method for increasing the thickness of the soft tissue of the mouth prior to performing block grafting procedures for dental implants. The method includes cutting a pair of incisions in the mucosa. A tunnel is formed through the mucosa which extends between, and connects, the pair of incisions. The tunnel is then extended coronally to undermine tissue covering the recipient site. An acellular dermal matrix is then sutured to an exposed end of a dental implement pulled through the tunnel to position the acellular dermal matrix within the tunnel. The acellular dermal matrix is then positioned over the recipient site using a periosteal elevator, and the acellular dermal matrix is fixed coronally by suspension sutures. The pair of incisions are closed with interrupted sutures, and a block graft is fixed to the recipient site by a pair of titanium screws.

A bone graft substitute for use in orthopedic bone grafting procedures comprising a radiolucent bone graft substitute combined with a temporary radiopaque agent. Methods of making and using the composition are also disclosed. Bone graft substitutes have become an effective means of regenerating bone in orthopedic procedures where bone loss results from surgically created defects or traumatic injury to the bone. Bone graft substitutes include mineral-based materials such as hydroxyapatite, calcium phosphates, and calcium phosphosilicates as well as allograft-derived materials and xenograft-derived materials such as collagen-based matrices and demineralized bone matrices.

A thoracic structure access system for retracting biological tissue and providing access to internal biological structures; particularly, intrathoracic structures, e.g., the heart and internal mammary arteries, to facilitate entry through the biological tissue with surgical instruments and interaction of the surgical instruments with the intrathoracic structures during a thoracic surgical procedure; particularly, minimally invasive CAGB and OPCAB procedures. The system facilitates coronary artery bypass graft (CAGB and OPCAB) procedures via a simple incision at a transxiphoid incision site and, hence, without fully transecting the sternum, i.e., performing a full sternotomy, or performing a thoracotomy. The system includes modular retractor and retention arm assemblies in communication with a ratchet assembly. When the system is disposed proximate a transxiphoid incision site and the modular retractor and retention arm assemblies are releasably engaged to opposing biological tissue portions at the transxiphoid incision site, the ratchet assembly can be actuated to apply opposing forces to the biological tissue portions to provide an access space at the transxiphoid incision site.

The invention discloses a bed nursing and rehabilitation integrated device for a patient after the clinical kidney transplantation operation. The device is characterized in that firstly, through the cooperative action of a second electric push rod, a protective cover and an air purifier, not only can a wound be isolated from the outside to achieve the purposes of preventing infection and pressure, but also the body of the patient can be fixed to effectively prevent the condition that secondary hurt is caused when the patient turns over in the sleeping process, the healing effect of the wound is also improved, secondly, by means of the combination of a second stepping motor, a third electric push rod, a fourth electric push rod, a first connecting frame and lower limb exercise sleeves, stretching exercise of the lower limbs of the patient can be achieved, blood circulation of the legs of the patient is promoted, and complications are effectively avoided; and finally, by means of a third stepping motor, a fifth electric push rod, a sixth electric push rod, a second connecting frame, regulation and control blocks, guide sleeves and telescopic rods, the upper limbs of the patient can be exercised, besides, convenient adjustment can be achieved, and the nursing and rehabilitation requirements of the patient after the clinical kidney transplantation operation are finally met.

A method for planning a bone grafting procedure includes the collection of imaging scan data of the target region and of a harvest region as a source for a bone graft complementary to the target region. Virtual bone model and harvest regions are generated. A computer processor determines at least one parameter for a bone graft model complementary to the target region. A location at the harvest region for the bone graft is identified based on the bone graft model. The location of the harvest region is registered to a first computer-assist device and the bone graft is harvested. The target region is registered to the first computer-assist device or another device. The cutting characteristics for the target region are communicated to the first computer-assist device or the other device to receive the bone graft. A surgical system for performing the computerized method is also provided.