33 results about "Extractive electrospray ionization" patented technology

An apparatus and method for direct analysis of continuous-flow liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS) including a sample stage that is adapted to receive a liquid sample and a nebulizing ionizer that is configured to generate a charged, nebulized solvent and thereby desorb at least a portion of the liquid sample from the sample stage.

The invention discloses an adjustable device used for an extractive electrospray ionization source. The adjustable device mainly includes a universal interface device, a base, a Y-direction adjustment device, an electrospray channel nozzle parameter adjustment device, and a sample channel nozzle parameter adjustment device. The Y-direction adjustment device is capable of adjusting the heights of an electrospray channel nozzle and a sample channel nozzle. The sample channel nozzle parameter adjustment device and the electrospray channel nozzle parameter adjustment device are capable of adjusting an angle Alpha of the sample channel nozzle and a mass spectrometer sample inlet port, a distance a between the sample channel nozzle and the mass spectrometer sample inlet port, an angle Beta between the electrospray channel nozzle and the sample channel nozzle and a distance b between the electrospray channel nozzle and the sample channel nozzle. The device is applicable to researches of a relation between specific parameters and a signal intensity in a mass spectrometry technology of different forms of samples such as liquid, aerosol, solid surface and viscous samples and the like and particularly suitable for real-time online monitoring of liquid samples.

The invention discloses an MRESI (multichannel rotating electrospray ionization) mass spectrometric analysis ion source. The ion source comprises a pedestal, a stepping motor, a coupling part, a voltage conducting part, a rear support part, a rear-end bearing, a middle shaft, a front support part, a front-end bearing, a spraying needle fixed part, spraying needles and a sample platform, wherein the pedestal supports a whole set of device, and a rotor of the stepping motor and the middle shaft are coaxial; the voltage conducting part is provided with at least one conductive contact, and the spraying needles are communicated with external voltage in an electric conductance manner through wires; the front support part is sleeved on the middle shaft and the spraying needle fixed part through the front-end bearing, the rear support part is sleeved on the middle shaft through the rear-end bearing so as to support on a coaxial direction along a revolving part of the stepping motor; the left end of the middle shaft is connected with the stepping motor through the coupling part so as to transfer the rotation to connect with the spaying needle fixed part of the right end of the middle shaft; and the spraying needle fixed part is provided with multiple grooves used for installing the spraying needles, and each spraying needle is mutually communicated with an outer placing injector through an individual pipeline. The device provided by the invention has the advantages of being capable of improving ionization efficiency, enhancing stability of mass spectrometric detection signals, being used for researching gas phase among different sprayings or liquid phase reactions as well as the detection of polycomponent of complicated samples or full component.

The invention relates to the field of analytical chemistry, and discloses an internal extraction electrospray ionization source and a mass spectrometry analysis method thereof. The internal extraction electrospray ionization source consists of a sampler handle 11, a quantitative sampler 12, a capillary holder 13, and an inner sleeve of the holder. Tube 14, extractant capillary 15, hand twist joint 16 and extractant passage 17 constitute, described sampler handle 11 and quantitative sampler 12 constitute sampling device, quantitative sampler 12, capillary tube holder 13, holder inner casing 14 , the extractant capillary 15 and the thumb joint 16 are sequentially connected and connected with the extractant passage 17. The invention guarantees the stability and reliability of the analysis results. The ionization source device has a built-in electrospray nozzle, which can be directly used to form electrospray after sampling, which is easy to operate and eliminates the influence caused by differences in texture or blood vessels of tissue samples. The invention improves the stability, quantitative ability and analysis speed of iEESI-MS, and expands the application range of iEESI-MS.

The invention relates to an electrospray extraction ionization-mass spectrum (EESI-MS) rapid detection method for alkaloid in lotus seeds, belongs to the technical field of analysis, and particularly relates to a rapid determination method for alkaloid in lotus seeds. The method comprises the following steps: processing a sample, processing a standard product, detecting by EESI-MS, drawing a standard curve, and calculating the concentration of alkaloid in a sample. The method provided by the invention is rapid and accurate without complex sample pretreatment, not only can be used for rapidly identifying the alkaloid in a complex matrix sample, but also can effectively differentiate lotus seed samples with different aging degrees by combining with chemometrics.

The invention belongs to the technical field of detection and discloses a method for directly detecting five kinds of chemical pollutants in propolis by electrospray extraction ionization mass spectrometry. The invention comprises the following steps: 1) preparation of standard solution; 2) preparation of propolis tincture; 3) preparation of standard propolis tincture; 4) electrospray extraction ionization mass spectrometry detection; 5) qualitative analysis; 6) quantitative analysis. The detection method of the invention has less sample consumption, fast analysis speed, and can realize high throughput and on-line detection. Direct analysis and detection of common propolis chemical pollutants without complicated sample pretreatment, and the detection time of a single sample is less than 1min. Non-toxic and non-polluting to products, operators and working environment; high sensitivity. The invention does not require complicated pretreatment of the sample to be tested, can withstand the influence of the complex matrix of propolis, realizes direct and rapid detection of chemical pollutants in propolis, and improves the defects of cumbersome sample pretreatment and long analysis time in the existing analysis technology.