30 results about "Chronic stage" patented technology

It is intended to provide a drug which is efficacious in treating and preventing diseases wherein ischemia or an inflammatory substance associated with ischemia participates in the onset or worsening thereof. Because of containing as the active ingredient a substance selected from among farnesol, a farnesol derivative, a tocopherol derivative, a tocotrienol derivative, pharmacologically acceptable salts thereof and solvates thereof, the above-described inhibitor of ischemic disorders can exert therapeutic and preventive effects on diseases wherein ischemia or an inflammatory substance associated with ischemia participates in the onset or worsening thereof (for example, brain infarction, brain edema, cardiac infarction, etc.) not only by the administration in the acute ischemic stage but also by the therapeutic administration in subacute and / or chronic stages after ischemia-reperfusion. It is also intended to provide a farnesol carboxylic acid ester derivative and a method of producing the same.

The peptidoglycan layer is a vital component of the bacterial cell wall, which comprises 4→3 and 3→3 transpeptide cross-linkages, the formation of which are catalyzed by D,D- and L,D-transpeptidases, respectively. Methods for the treatment of bacterial infections with agents that inhibit L,D-transpeptidases, either alone or in combination with D,D-transpeptidase inhibitors, are provided herein. Also provided are methods for the treatment of chronic stage tuberculosis with agents that inhibit enzyme with L,D-transpeptidase activity.

A method to treat the chronic stage of heart injury after ischemia or reperfusion by administering Midkine to a subject in need of such treatment is described.

An orally taken Chinese medicine for treating viral myocarditis is prepared from 5-7 Chinese-medicinal materials including American ginseng, gypsum, arnebia root, borneol, etc. Two prescriptions for different stages are disclosed.

The present invention relates to a method for treating a patient having suffered from severe aphasia associated with cerebrovascular accident chronic stage for at least three years, wherein said treatment consists essentially of administering a composition comprising 2-oxo-1-pyrrolidineacetamide as an active ingredient and a pharmaceutically acceptable carrier.

The compound Chinese onion preparation for treating chronic obstructive lung disease is prepared with Chinese onion, trichosanthes peel, Chinese goldthread, immature bitter orange, cassia twig and other chinese medicine materials. The preparation process includes crushing material, ethanol extraction, depression recovery of ethanol, concentration, adding supplementary material, vacuum drying to obtain dry extract, crushing, and further steps to prepare tablet, capsule, drip pills and micro pills. The compound Chinese onion preparation has obvious functions of relieving cough, eliminating phlegm and relieving asthma, and may be used to treat chronic obstructive lung disease effectively. It is ideal medicine for COPD in acute stage and COPD in prolonged stage and chronic stage.

The invention particularly relates to a compound pumpkin vine ointment and a preparation method thereof. Every 1000 parts by weight of ointment comprises the following active pharmaceutical ingredients in parts by weight: 51.73-71.73 parts of pumpkin vine (carbonized), 39.38-49.38 parts of mirabilite, 2.35-22.35 parts of Chinaberry seed (carbonized), 10.58-30.58 parts of phenol, 155.76-255.76 parts of flour, and the balance of water and caramel. The preparation method comprises the following steps: adding mirabilite into a certain amount of water, heating to dissolve the mirabilite, filtering, and collecting the filtrate; adding pumpkin vine (carbonized) and Chinaberry seed (carbonized) which are pulverized into fine powder and screened, evenly mixing, adding a right amount of caramel, evenly mixing, and adding flour while evenly stirring; and finally, adding phenol, and evenly mixing to obtain the compound pumpkin vine ointment. The compound pumpkin vine ointment has comprehensive and unique effects on diminishing inflammations, removing toxicity, promoting the subsidence of swelling, alleviating pain, evacuating pus, promoting blood circulation and dredging collaterals for ulcerand furuncle, and can be effectively used in acute and chronic stages of ulcer as well as early, medium and later stages of ulcer. The compound pumpkin vine ointment can quickly take effect, and is not irritating to skin.

The invention discloses a preparation method of a controlled-release capsule with functions of detoxifying and diarrhea stopping. The controlled-release capsule is prepared from scabrid smallhooked hedyotis herb and auxiliary materials. According to the property of the scabrid smallhooked hedyotis herb, an extraction technology is optimized. Furthermore, aiming at the problem that the existing form bioavailability is low, one part of the scabrid smallhooked hedyotis herb is prepared into a quick-release pellet, the other part of the scabrid smallhooked hedyotis herb is prepared into a controlled-release pellet, and the two pellets are filled to prepare the capsule, so that the controlled-release capsule can be taken by patients in both of the acute stage and the chronic stage of colitis gravis, and therefore, the effect of treating both symptoms and root causes can be achieved, and the recurrence of the colitis gravis can be more effectively cured.

The present invention discloses the application of kidney reinforcing and rheumatism treating bolus in treating gout in chronic period. The kidney reinforcing and rheumatism treating bolus is prepared with angelica, ground beetle, white stiff silkworm, honeycomb, black tail snake and other Chinese medicine materials. It has obvious curative effect on gout in chronic period, and when it is taken together with available gout treating medicine granule, even high curative effect will be resulted in.