Semi-quantitative detection kit for bleaching toner residue in Chinese medicinal materials or Chinese medicinal decoction pieces

A technology of semi-quantitative detection and Chinese herbal decoction pieces, which is applied in the field of physical and chemical analysis of chemical substances, can solve the problems of safe use of Chinese herbal medicines, hidden dangers of Chinese herbal medicine decoction pieces, high processing conditions for toxic reagent tetrachloride amalgam, expensive equipment, etc., to eliminate Effects of color background interference, elimination of background color interference, and shortened detection time

Inactive Publication Date: 2011-08-17
广东省药品检验所
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Similarly, it also brings great hidden dangers to the safe use of Chinese herbal medicines and Chinese herbal medicines
At present, the legal method to detect whether there is sulfur dioxide residue in Chinese herbal medicines and herbal pieces is the distillation titration method. This method uses a glass instrument device, which is large in size, has many connecting parts, and uses nitrogen gas. The operation time is too long and must be carried out in the laboratory. and some studies try to learn from the rose paraaniline colorimetric method or ion chromatography detection of sulfur dioxide in food, but either use the toxic reagent tetrachloro amalgam and the processing conditions are relatively high, or the equipment used is expensive and has a large volume , The detection environment has high requirements and the processing conditions are strict, so it is not convenient to carry out on-site supervision and use
At present, there is no research on simple and rapid detection methods using chemical methods, especially no research on the use of filter paper as a carrier for separation, diffusion, and chemical reaction color development to simultaneously semi-quantitatively detect the residual inorganic chemical components of Chinese herbal medicines and Chinese herbal medicines. Therefore, this paper The study of the law has more practical significance for supervising on-site rapid detection, timely detaining unscrupulous merchants for illegal processing, and using bleaching and coloring agents for Chinese medicinal materials and Chinese medicinal pieces.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Semi-quantitative detection kit for bleaching toner residue in Chinese medicinal materials or Chinese medicinal decoction pieces
  • Semi-quantitative detection kit for bleaching toner residue in Chinese medicinal materials or Chinese medicinal decoction pieces
  • Semi-quantitative detection kit for bleaching toner residue in Chinese medicinal materials or Chinese medicinal decoction pieces

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1: One of the semi-quantitative detection kits for bleaching and color enhancing agent residues in Chinese herbal medicines and Chinese herbal decoction pieces

[0042] preferred embodiment

[0043] This embodiment is a preferred embodiment of the semi-quantitative detection kit for bleaching and coloring agent residues in Chinese medicinal materials and Chinese medicinal decoction pieces. The kit includes a cecillin bottle with sodium hydroxide solution, a With cecillin bottle, hydrochloric acid solution and lead acetate test paper. Wherein, the mass volume percentage concentration of sodium hydroxide solution is 0.125%, and its volume is 10ml, and the specification of the Cecillin bottle that this sodium hydroxide solution is housed is 15ml. The specification of the Cecillin bottle containing the arsenic-free zinc granules is 10ml, and the total mass of the arsenic-free zinc granules is 0.2g. The lead acetate test paper is a qualitative filter paper with a d...

Embodiment 2

[0044] Embodiment 2: Utilize the kit in this embodiment 1 to carry out the color reaction of standard substance

[0045] In this embodiment, sodium sulfite and sodium bisulfite are used as standard products. Take about 10 g of standard sodium sulfite and sodium bisulfite, put them in 100ml measuring bottles, add an appropriate amount of purified water or distilled water to dissolve and dilute to the mark, and use them as respective standard stock solutions.

[0046] Take the above stock solution and prepare the mass volume percentage concentration as 0.0001%, 0.0002%, 0.0005%, 0.001%, 0.002%, 0.005%, 0.01%, 0.02%, 0.05%, 0.1%, 0.2%, 0.5%, 1% , 2%, 5%, 10% and other standard solutions, and take 2ml respectively to carry out the color reaction according to the following steps:

[0047] (1) Sample processing

[0048] The sampling volume of Chinese herbal medicines and Chinese herbal medicine pieces is about 1g. Cut (or grind) the sample into fine particles with scissors (or gr...

Embodiment 3

[0054] Embodiment 3: Utilize the kit in this embodiment 1 to carry out the color reaction of sample

[0055] First, prepare the test solution. Put the treated sample in a cecillin bottle filled with 10ml of 0.125% sodium hydroxide solution, the size of the bottle is 15ml, tighten the stopper, shake vigorously for 1-2 minutes, let it stand for a while, and wait for the layers to separate , Take 2ml of the upper layer solution (filtered if necessary) as the test solution. A color reaction is then performed. Put 2ml of the above test solution into a vial containing arsenic-free zinc pellets, wherein, 2 pellets of arsenic-free zinc pellets, about 0.2g, the specification of the vial is 10ml, then add 2ml of hydrochloric acid solution, gently Shake to make the mixture even, and immediately put the lead acetate test paper tightly on the mouth of the bottle. Final judgment result. If it turns yellow-brown to silver-black within 10 minutes, it can be judged that the sample may cont...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
Login to view more

Abstract

The invention provides a semi-quantitative detection kit for bleaching toner residue in Chinese medicinal materials or Chinese medicinal decoction pieces. The kit comprises a stopper-containing penicillin bottle filled with sodium hydroxide solution, a stopper-containing penicillin bottle filled with arsenic-free zinc granules, hydrochloric acid solution and lead or copper ion test paper. The mass volume percentage concentration of the sodium hydroxide solution is 0.125 percent, the volume of the sodium hydroxide solution is 10 milliliters, and the specification of the stopper-containing penicillin bottle filled with the sodium hydroxide solution is 15 milliliters. The total mass of the arsenic-free zinc granule is 0.1 to 0.3 gram, and the specification of stopper-containing penicillin bottle filled with the arsenic-free zinc granules is 10 millimeters. The lead or copper ion test paper is lead acetate test paper, copper acetate test paper or copper sulfate test paper. The kit is convenient to carry, and has the advantages of simple operation, quick detection, low cost, semi-quantitative measurement, high accuracy and the like; and the kit greatly shortens the detection time, is suitable for supervision and quick field screening of the bleaching toner residue in the Chinese medicinal materials or the Chinese medicinal decoction pieces, and is suitable for semi-quantitative analysis at the same time.

Description

technical field [0001] The invention relates to physical and chemical analysis of chemical substances, in particular to a semi-quantitative detection kit for residual bleaching and coloring agents in Chinese herbal medicines and herbal pieces. Background technique [0002] Scientific studies have shown that long-term or high-dose intake of sulfite can cause damage to the gastrointestinal tract and liver, and sulfur dioxide can damage the reproductive system of male mice. Since the 1980s, research on the safety of sulfites has attracted more and more attention from various countries. [0003] The traditional processing methods of sulfur fumigation or soaking Chinese herbal medicines will lead to a large amount of sulfur dioxide, arsenic, mercury and other toxic and harmful substances remaining in the original medicine of Chinese herbal medicines. Therefore, "The Pharmacopoeia of the People's Republic of China" (2000 Edition) stipulates that, except for yam, all other traditi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/78
Inventor 林奇艺林锦锋严全鸿谢志洁
Owner 广东省药品检验所
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap