The invention discloses an invisible orthodontic appliance for dental orthodontics and a manufacturing method of the invisible orthodontic appliance, and is characterized in that transparent upper and lower jaw orthodontic tooth sockets, namely invisible orthodontic appliances (1a and 2a), are provided with bulges with specific shapes, namely upper jaw bulges (3 and 4) and lower jaw bulges (5 and 6), and the bulges are arranged in pairs between the upper and lower orthodontic tooth sockets; the shape features of the protrusions enable the protrusions to interact with each other, so that thrust is generated, teeth are pushed, namely orthodontic force is generated, in the orthodontic treatment process, the thrust can enable the stressed teeth to move, the purpose of orthodontic treatment is achieved, the protrusions on the orthodontic tooth socket can be manufactured and achieved through a mold core and a patient tooth mold in a specific shape, and the orthodontic tooth socket is simple in structure and convenient to use. The invisible orthodontic appliance utilizes the physiological force of a patient, is non-invasive, does not need any other external force and anchorage, is simple in structure and simple in manufacturing method, and can be seamlessly connected with a manufacturing method of a popular invisible orthodontic appliance.