A selective
nerve stimulation patch includes a substrate having a top surface and a bottom surface, integrated components overlying the top surface of the substrate and being electrically interconnected with one another for generating at least one nerve stimulating
signal, electrodes integrated into the substrate and exposed at the bottom surface thereof for applying the at least one nerve stimulating
signal to a target nerve, a waterproof, breathable cover overlying the substrate and the integrated components, and a support
flange surrounding the substrate and
coupling the cover and the substrate together. The support
flange has a top surface that slopes downwardly toward an outer perimeter thereof, and at least a portion of the cover conforms to the sloping top surface of the support
flange. In one embodiment, the patch generates a
high frequency waveform with properties such as amplitude, frequency and the like chosen so as to overcome
tissue impedance and the stimulation threshold of the target nerve. The modulated waveform is the waveform obtained by modulating the carrier waveform by a
pulse envelope.