89 results about "Gastric Content" patented technology

Pyloric valve corking devices and methods are described herein. The devices generally include an occluding member which expands from a first configuration to a larger second configuration and a bridging member extending from the occluding member. The bridging member has a length which passes at least partially through the gastric opening such that the occluding member obstructs the gastric opening, and wherein the length permits the occluding member to intermittently move relative to the gastric opening. A second occluding member may be attached to the distal end of the bridging member. The reduction in flow of gastric contents into the duodenum can be tightly regulated using a pump or valve. Otherwise, the flow can be passively regulated with the occluding device.

Pyloric valve corking devices and methods are described herein. The devices generally include an occluding member which expands from a first configuration to a larger second configuration and a bridging member extending from the occluding member. The bridging member has a length which passes at least partially through the gastric opening such that the occluding member obstructs the gastric opening, and wherein the length permits the occluding member to intermittently move relative to the gastric opening. A second occluding member may be attached to the distal end of the bridging member. The reduction in flow of gastric contents into the duodenum can be tightly regulated using a pump or valve. Otherwise, the flow can be passively regulated with the occluding device.

The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.

A method for treating a patient includes creating at least one incision to gain access to an petitoneal cavity, performing a gastric volume reduction procedure and introducing a device to prevent gastric contents from interacting with at least a portion of the duodenum.

Pyloric valve corking devices are disclosed herein that generally include an occluding member, expanding from a first configuration to a larger second configuration, and a bridging member extending from the occluding member. The bridging member has a length that is adapted to pass at least partially through the gastric opening, so to enable the occluding member to obstruct the gastric opening, and that is also adapted to permit the occluding member to intermittently move relative to the gastric opening. A second occluding member may be attached to the distal end of the bridging member. The reduction in flow of gastric contents into the duodenum can be actively regulated using a pump or valve, or can be passively regulated with movements of the occluding device.

The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.

The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.

Disclosed is an esophageal stent placed in a stenosed part of the esophagus having a flexible tube to prevent the reverse flow of gastric contents from the stomach is coupled to the lower end of the esophageal stent. The flexible tube has an inside membrane and an outside membrane adhered to each other, thus having a twofold structure with at least one core longitudinally placed between the adhered inside and outside membranes while the core extends from the upper end toward the lower end of the flexible tube. Thus, the flexible tube is prevented from being inverted, and prevents the reverse flow of the gastric contents, and maximizes the operational reliability of the esophageal stent. The flexible tube does not cause a patient pain or discomfort due to frictional contact of the tube with the inner surface of the stomach when the tube moves in the stomach.

The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.

An enteral tube includes a built-in Gastric Residual Volume (GRV) detection sensor at the distal end and a GRV indicating device at the proximal end for indicating the current GRV without requiring the aspiration of any stomach contents. The enteral tube with integrated GRV detection sensor is flexible and long enough to be looped around within the stomach. Weights may be employed to keep the sensor located generally at the lowest portion of the gastric cavity. The GRV detection sensor may include a sealed air column terminating with a flexible membrane. When the enteral tube and sealed air column are inserted into the stomach and submerged in gastric contents, pressure is exerted against the flexible membrane, and therefore against the sealed air column. A pressure sensor detects the pressure within the sealed air column and provides a signal or level representative of the amount of gastric contents in the stomach.

An endoscopic guide for natural orifice transluminal endoscopic surgery. The device is a semi-flexible over-tube extending from the incisors through stomach and into the peritoneum. The over-tube has an inflatable balloon at its midpoint to occlude the esophageal lumen and prevent potential reflux of gastric content into the esophagus. The distal end is surrounded by two narrow inflatable balloons that are utilized on either side of the gastrotomy to keep the device in place with its lumen open into the peritoneum. The over-tube has a valve at the proximal opening that prevents leakage or peritoneal insufflation. The over-tube sheaths and protects the esophagus and guides instruments into the peritoneum. This device avoids re-intubation of the esophagus, promotes safe and easy access with increased efficiency and accuracy of insertion of the endoscope and other instruments, minimizes risks of perforation or other mucosal injuries, and allows secure control of the gastrotomy.

An esophageal gastric tube includes lumens for suction, venting and auscultation. The auscultation lumen serves as a conduit for electrical conductors to a thermistor positioned distally of the lumen for measuring core temperature without occlusion of the lumen. A stethoscope membrane encircles the tube, forming a sound chamber. Suction and vent lumens extend from the proximal tube end to the distal tip, while the stethoscope lumen terminates at the sound chamber distal end, for reducing suction noise interference with auscultation. A longitudinal slot in the tubular sidewall enables effective communication between the sound chamber and the stethoscope lumen. The stethoscope membrane includes internal circumferential ribs preventing occlusion of the slot and permitting 360° auscultation. The tube distal sidewall is apertured into the suction lumen, enabling suctioning of the gastric contents. Vent and suction lumens communicate within the distal end of the tube to provide an internal vent for relieving negative stomach pressure.

An enteral tube includes a built-in Gastric Residual Volume (GRV) detection sensor at the distal end and a GRV indicating device at the proximal end for indicating the current GRV without requiring the aspiration of any stomach contents. The enteral tube with integrated GRV detection sensor is flexible and long enough to be looped around within the stomach. Weights may be employed to keep the sensor located generally at the lowest portion of the gastric cavity. The GRV detection sensor may include a sealed air column terminating with a flexible membrane. When the enteral tube and sealed air column are inserted into the stomach and submerged in gastric contents, pressure is exerted against the flexible membrane, and therefore against the sealed air column. A pressure sensor detects the pressure within the sealed air column and provides a signal or level representative of the amount of gastric contents in the stomach.

This invention provides formulations and methods for stabilizing viruses in liquid and dried formulations. In particular, formulations are provided including Zn2+ cations that stabilize the viability of Rotaviruses. Methods of vaccination include neutralization of gastric contents and administration of the vaccine formulations of the invention.

An airway device configured for intubation under blind or optionally under indirect vision of a fiber optic scope. It also configured to be used as a supraglottic airway device supporting external breathing or anesthesia circuits. The device comprises a tube system with expansion projections, a base, one or more inflation balloons, and a gastric suction tube. The device can include a stylet to guide endotracheal tube during intubation. The tube system can include an air tube and fiber-optic-probe tube. The balloon system can move the end of the tube system anteriorly to align it with the laryngeal opening. The balloon system can seal the airway leakage for low positive pressure ventilation for the device to operate as a supraglottic airway device. The inflation balloon and expansion projection can displace tissue that can block the airway path. The base can carry esophageal gastric drainage tube to the upper esophageal sphincter to block and drain gastric content regurgitation.

The invention provides a multifunctional nasal feeding tube and a nasal feeding system. The multifunctional nasal feeding tube is characterized in that a tube body of the nasal feeding tube is internally provided with a non-return valve; an airbag is arranged at the outer side of the tube body of the nasal feeding tube; the airbag is connected with a pressurizing airbag through an air guiding tube. The non-return valve can be used for preventing nutrient solution in the nasal feeding tube from reflowing; the airbag at the outer side of the tube body of the nasal feeding tube is inserted in the position of stomachus cardiacus; after the inflation of the pressurizing airbag, the situation that gastric contents at the outer side of the nasal feeding tube are sucked into a lung by mistake due to reflow can be effectively prevented. According to the multifunctional nasal feeding tube and the nasal feeding system, aspiration complications caused by enteral nutrition support therapy through nasal feeding can be prevented specifically; the lung infection, severe pneumonia, even asphyxia caused by aspiration progress are effectively reduced, and the death rate is lowered. The multifunctional nasal feeding tube and the nasal feeding system can be widely suitable for popularization and application of clinical enteral nutrition support therapy. Moreover, the nasal feeding tube is further provided with an injector joint and a drug administration joint, so that the drug administration operation is conveniently performed on a patient who cannot swallow drugs independently. A feeding material supply system is arranged in the nasal feeding system, nutrients can be continuously fed to the patient after the connection with the nasal feeding tube, and the feeding efficiency is improved.

Type 2 diabetes mellitus and obesity are important diseases which are severe threats to human health in the world. Although the Type 2 diabetes mellitus and obesity have been treated and prevented by many measures, these measures have inevitable shortcomings. The invention discloses an instrument for delaying gastric emptying and regulating pancreatic metabolism. The instrument mainly consists of a skeleton (1) and a coated tube (2), and can be divided into a gastric pyloric tube section (3), pyloric exit (4) and small intestine (5) from the axial direction. By implanting the instrument, gastric emptying can be delayed, early satiety can be induced, the gastric content can be turned into duodenal distal segment or jejunum proximal segment, and the pancreatic metabolism can be regulated. With the instrument of the invention, the mechanical stimulation and injury of gastrointestinal casing to mucous membrane of stomach and intestines can be reduced to a greatest extent, and the complications after implantation, such as abdominal pain, vomit, etc., can be reduced.

A tube for use in gastrointestinal tract which allows administration of nutritional, medicinal, or other agent into gastrointestinal tract while preventing detention of digestive juices in esophagus, and which also prevents reflux of gastric contents.A detention-proof lumen is provided in tube body 12 of gastrointestinal tract tube 10 furnished with tube body 12 equipped with main lumen 12b and expansion lumen, such as balloon lumen 12c, and with an expander such as balloon 15 expanded by delivery of liquid or gas via the lumen provided on outer circumferential surface of tube body 12. Said detention-proof lumen communicates from a part more toward the base than the part where expander is provided on outer circumferential surface of tube body 12 to a part more toward the tip than part where the expander is provided on outer circumferential surface of tube body 12. An inner tube 18 used for liquid supply is provided movably within tube body 12.

Systems and methods for the treatment of gastroesophageal reflux disease (GERD) include at least one electrically stimulating electrode coupled to a pulse generator. Individuals with GERD are treated by implanting a stimulation device within and / or proximate the patient's lower esophageal sphincter, gastric fundus, or other nearby gastrointestinal structures and applying electrical stimulation to the patient's lower esophageal sphincter and / or fundus, in accordance with certain predefined protocols. Electrical stimulation provided by the disclosed systems results in an increase in the length of the high pressure zone of the LES and / or modulation of the receptive relaxation response of the fundus to decrease gastric pressure, creating a longer barrier to the reflux of gastric contents or increasing functional lower esophageal pressure respectively, thereby treating GERD.

The invention discloses an intraesophageal stent used for esophageal rupture and stomal leak plugging and relates to a hollow or tubular prosthesis which can be implanted into a body, in particular to the intraesophageal stent used for lower esophageal rupture and esophageal stomal leak plugging. The intraesophageal stent comprises a stent main body and a backflow prevention device, wherein the stent main body is made of a degradable material; the stomach end of the intraesophageal stent is provided with a dumb-bell-shaped fixed structure and an intragastric part; the dumb-bell-shaped fixed structure consists of a bulb of a dumb-bell and a notch part of the dumbbell; after the stent is implanted, the notch part of the dumb-bell is clamped at a cardia position or a gastroesophageal joint position; the intragastric part is a skirt-like opening extending and expanding into a gastric cavity from the notch part of the dumbbell; after the stent is implanted, the skirt-like opening is put in the gastric cavity, and an intragastric leak seal plugging structure is formed at the joint of esophagus and the stomach; the near end of the intraesophageal stent is provided with an anti-shifting line. The intraesophageal stent disclosed by the invention can be firmly fixed, so that the stent is effectively prevented from shifting; the expanding edge of the skirt-like opening of the intragastric part can play a role of stomal leak plugging, so that the phenomenon that gastric content flows back after the stent is implanted can be effectively prevented.

The invention relates to a stomach tube with a device for preventing the backflow of gastric content, which is divided into a head part, a middle part and a tail part. The stomach tube is characterized in that a main channel for infusing nutrient solutions, water and medicaments is penetrated through the head part, middle part and tail part in the stomach tube; the head part is provided with two parallel cavities; the upper end opening of the main channel is communicated with the head part of the stomach tube and is open at a main cavity of the two parallel cavities; a subsidiary cavity for infusing gas is further arranged in the two parallel cavities at the head part of the stomach tube; the subsidiary cavity is provided with a charging connector having a locking device; the subsidiary cavity is communicated with an umbrella-shaped backflow-preventing device around the outer wall at the middle lower part of the stomach tube through a gas bag channel positioned in the wall of the stomach tube; and the tail part of the stomach tube is provided with the lower end opening of the main channel. The invention can effectively solve the serious clinical problem such as suffocation, inhalation pneumonia and the like caused by mistakenly inhaling gastric content backflow into the trachea.

The invention relates to a transpyloric device for accepting chyme from the stomach and conducting said chyme on in a bypass-like manner through a patient's duodenum; said device is held in place by balloon segments which sit on a preferably radially collapsible and self-erecting transpyloric conducting element; the filling level of the balloon segments, and thus the axial sealing force acting primarily on the shoulder surfaces of the pylorus or the surrounding area thereof, can be adjusted by the user, and the force applied to the stomach and duodenum structures adjoining the pylorus is reduced to a level that is permanently bearable for the organs even when the filling pressure of the segments rolling against each other is elevated. The invention also relates to an applicator for putting a bypass device of said type in place in the region of the transition from the stomach to the duodenum.

The invention relates to a self-retracting intraesophageal bracket capable of carrying radiation elements for partial radiotherapy. The self-retracting intraesophageal bracket comprises a top ring, a force transmission plate, a bracket body and a thin-film sleeve sleeved on the bracket body, wherein medicine-carrying thin tubes are uniformly distributed on the outer wall of the thin-film sleeve; radiotherapy medicine is loaded in the medicine-carrying thin tubes; the top ring is arranged at one end of the bracket body; the force transmission plate is arranged on the top ring in a penetrating manner through a socket ring; the bracket body consists of telescopic units; each telescopic unit consist of two clamp arms and a plurality of clamp rings; the two clamp arms are in hinge joint; and the lower end of the force transmission plate is arranged on the clamp rings of the telescopic unit at the uppermost end. According to the self-retracting intraesophageal bracket disclosed by the invention, the esophageal stenosis passage can be effectively expanded during food taking, and the esophageal stenosis passage is closed at no food taking state, so that the backflow of gastric content can be effectively prevented, and foreign body sensation of a patient at on food taking state is obviously alleviated; and meanwhile, the radiotherapy medicine is carried by the intraesophageal bracket, plays the effect of partial radiotherapy while support expansion is performed on esophagus, and provides a better route of medication for tumor radiotherapy.

The invention discloses an outer sleeve for a gastroscope. The whole outer sleeve is in the shape of a hollow tube. The inner diameter of the sleeve is 1.1 cm, the inner circle and the outer circle of the sleeve are not concentric, the sleeve with uneven wall thicknesses is formed, the thickness of the position where the wall is thick is 5 mm, and the thickness of the position where the wall is relatively thin is 3 mm. A washing channel is formed in the position, wherein the wall is thick, in the sleeve wall, and the washing channel extends to the bottom of the outer sleeve from the inlet end of the gastroscope. The position, close to a gastroscope inlet, of the wall where is thin is provided with a water filling pipe. The gastroscope inlet and an inlet of the washing channel are provided with silica gel plugs, and the silica gel plugs are covered with cross-shaped openings in the centers. On one hand, the washing channel in the outer sleeve can be used for washing blood, digestive juice, mucus and the like within view, and the view is kept clear; on the other hand, instruments can be delivered, the complexity and the difficulty for endoscope part treatment can be lowered, normal saline and the like are filled through the water filling pipe, the friction force between the outer sleeve and the endoscope can be lowered, the endoscope can move more smoothly and more freely, and the arranged plugs can effectively prevent injected liquid or gastric content from overflowing.

The invention relates to a preparation method of vegetable bread. The main ingredients of the vegetable bread comprise sweet potato or pumpkin 1000-2000g, berry sugar 300-750g, butter 20-80g and instant custard powder 60-80g. The sweet potato or the pumpkin is immersed in light salt brine for 10 minutes to kill oxidase in the sweet potato, the sweet potato is taken out and steamed, the steamed sweet potato is placed in a blender to be stirred into pulp, the berry sugar and the butter are placed into the pulp and are uniformly mixed, and eventually the instant custard powder is fully and uniformly mixed and is freezed to be used. The pumpkin contains large amount of pectin, when the pumpkin and starchy food are taken simultaneously, viscosity of gastric content is improved, absorbing for carbohydrate is slowed down, the pectin forms gelatinoid in an intestinal tract, absorbing for the carbohydrate and lipid is slowed down, and rising of blood fat and blood sugar can be controlled. Varieties and content of vitamin and amino acid in the sweet potato are both higher than those of polished round-grained rice and wheat flour, the content of the vitamin and cellulose is extremely high, and the sweet potato contains iron, calcium and other microelements which are essential for a human body. The sweet potato is treated as nutrition and health care food abroad.

The invention relates to the technical field of medical apparatus, in particular to a gastroscope bushing which can prevent backstreaming and miss inhalation during the gastroscope examination. The gastroscope bushing is composed of a bushing (1), a bushing fixing buckle (2), a cardia gasbag (3), a gullet gasbag (4), two gasbag inflation tubes (5), a corresponding air pressure indicating gasbag (6) and an inflation valve (7), wherein, the bushing (1) takes the shape of a hollow column and is sleeved outside the gastroscope and the tail end of the bushing (1) is provided with a ring-shaped grasping ring (1.1); the bushing fixing buckle (2) is positioned at the top end of the bushing and the top end of the bushing is fixed at the top end of the gastroscope by the clamping of a pair of biopsy forceps; the cardia gasbag (3) can plug a cardia mouth after being inflated, thereby preventing gastric content from backstreaming; the bushing can be fixed in the gullet, so as to prevent the cardia gasbag from displacing after the gullet gasbag (4) is inflated; the front ends of two gasbag inflation tubes (5) are respectively connected and communicated with the cardia gasbag and the gullet gasbag, and the rear ends thereof dissociate outside the tail end of the bushing and are connected with the inflation valve (7) by the air pressure indicating gasbag (6) for the inflation of the gasbag. The gastroscope bushing has simple structure and convenient use and is capable of preventing the backstreaming and miss inhalation risks of patients with full stomach during the gastroscope examination effectively.