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61 results about "Ear infection" patented technology
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Invasion and growth of microorganisms in the ear; may be clinically inapparent or result in local cellular injury; may result in hearing loss or deafness.
Foamable compositions containing vitamin D3 analogues, processes for preparing same and methods of treatment utilizng same
A pharmaceutical or cosmeceutical foamable composition for topical application of vitamin D3 analogues such as calcipotriene and a process of manufacturing the same is disclosed. A method of treatment of skin and scalp disorders, especially of psoriasis or ear infections, by dispensing vitamin D3 analogues such as calcipotriene in a foamable composition is also disclosed.
Owner:AGIS INDUSTRIES (1983) LTD
Dispersible pharmaceutical compositions
ActiveUS7842791B2Good dispersionEfficacious level of antibacterialAntibacterial agentsOrganic active ingredientsDiseaseMicrocrystalline wax
A pharmaceutical composition is provided comprising a vehicle that comprises (a) an amphipathic oil that is water dispersible and ethanol insoluble, (b) microcrystalline wax, and (c) a pharmaceutically acceptable non-aqueous carrier; and having an antibacterial substance in an antibacterially effective amount stably dispersed in the vehicle. The composition is suitable for administration by intramammary infusion to a milk producing animal for treatment and / or prevention of mastitis or other diseases of the udder, as well as for otic administration for treatment and / or prevention of an ear infection.
Owner:ZOETIS SERVICE LLC
Apparatuses and methods for mobile imaging and analysis
ActiveUS9445713B2Reduce dimensionalityEasy to separateImage enhancementImage analysisDiseaseImaging analysis
Apparatuses and methods for mobile imaging and image analysis. In particular, described herein are methods and apparatuses for assisting in the acquisition and analysis of images of the tympanic membrane to provide information that may be helpful in the understanding and management of disease, such ear infection (acute otitis media). These apparatuses may guide or direct a subject in taking an image of a tympanic membrane, including automatically detecting which direction to adjust the position of the apparatus to capture an image of the tympanic membrane and automatically indicating when the tympanic membrane has been imaged.
Owner:JOHNSON & JOHNSON CONSUMER COPANIES
Compositions and methods for treatment of ear canal infection and inflammation
InactiveUS20090111780A1Eliminate negative effectsAlleviate occurrence effectBiocideHydroxy compound active ingredientsInflammationAnti-inflammatory analgesics
The present invention relates to compositions and methods for treatment of ear infections and inflammation. Specifically, the method involves administering to a patient a composition containing an antibacterial, an anti-inflammatory, and an anti-septic that is substantially free of pramoxine to treat the occurrence or negative effects of otic infection and inflammation.
Owner:EVERETT LAB
Otic formulations, methods and devices
ActiveUS20130178801A1Significant pain reliefLess bacterial community resistanceAntibacterial agentsBiocideThiocarbamateAntifungal
The present invention relates to a formulation and method for treating an ear infection, especially otomycosis and otitis externa, by administering a one-time only treatment comprising an antibiotic, and antifungal, and an anti-inflammatory in a thick, otic carrier. In one embodiment, the formulation comprises a therapeutically effective amount of active ingredients including a fluoroquinolone, a triazole antifungal, a thiocarbamate antifungal, a corticosteroid and a polyene antifungal, as well as a thickener such that the formulation, upon applying to the infected ear canal, gels and remains in the ear canal, continuously releasing the active ingredients for several days, achieving consistent complete (98-100%) clinical resolution of otomycosis and otitis externa in a single application.
Owner:METALCLAD
Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections
Efflux pump inhibitors are co-administered with antimicrobial agents for the treatment of ophthalmic or otic infections. The agents may be co-administered directly to the site of infection (e.g., the eye or ear).
Owner:REMPEX PHARM INC
Adherent polyol troche
ActiveUS20070274927A1Low dissolution rateReduce solubilityAntibacterial agentsSenses disorderPacifierBi layered
A slow-dissolving troche with polyol molecules is disclosed. It may be an adherent troche, preferably adhered to teeth or gums or cheek with acacia gum, or a lollipop or child's pacifier. Consumers are instructed to use the troches at the end of each day and after each meal, at least four times per day to benefit oral health, particularly caries, gingivitis, periodontitis, ear infections, sinus infections, halitosis and risk of Streptococcus mutans infecting their blood from their mouths. The polyol molecules are preferably xylitol. The troches may be made with a bi-layer tablet press rounded on one side and flat on the other, preferably using acacia gum in the flat side layer for adhesion.
Owner:ORAHEALTH LLC
Device for measuring and analysing the colour of the outer ear and ear canal
ActiveUS8617061B2Simplify the diagnostic processAutomatically performBronchoscopesLaryngoscopesOtoscopeMedicine
Owner:UNIV DO PORTO
Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
The present invention discloses ophthalmic and otic compositions of facially amphiphilic antimicrobial polymers and oligomers and their uses, including their use in methods for treating and preventing ophthalmic infections and otic infections in humans and animals.
Owner:POLYMEDIX
Hybrid Compounds And Methods Of Making And Using The Same
InactiveUS20140171438A1Reduce spreadInhibit tumor growthAntibacterial agentsBiocideHybrid compoundMycobacterium Infections
The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, malaria, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; killing or inhibiting the growth of a Plasmodium species; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin / low molecular weight heparin derivative.
Owner:CELLCEUTIX CORP
Optical ear infection treatment device and method
InactiveUS20080097414A1Reduce bacterial growthKill bacteriaSurgical instrument detailsLight therapyLight pipeControl electronics
Optical ear infection treatment device and methods are described where an LED and optical light pipe are used to deliver the light from the LED to the middle ear of a patient to reduce bacterial growth and / or eliminate bacteria. Typically, the device is placed in the ear and then activated by the user by pressing an activation button. Once activated the control electronics will turn on the LED and perform a treatment. The most basic treatment mode comprises turning on the LED at maximum power for a predetermined period, e.g. 30 minutes, 60 minutes. When the preset duration is completed, the device will notify the user by an audible beep or vibration that the treatment is complete. Once completed, the user can remove the device, the treatment could be repeated once a day or for extreme cases multiple times during the day.
Owner:CHOI GEORGE YOSEUNG
Bacteriophage-containing therapeutic agents
The present invention relates in its broadest aspect to combined phage / antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.
Owner:BIOCONTROL
Compositions for treatment of ear infections
InactiveUS20070212343A1Facilitate trans-tympanic deliveryBiocideSenses disorderMoxifloxacinTreatment level
Topical otic pharmaceutical compositions comprising moxifloxacin or a pharmaceutically useful hydrate or salt thereof and a proteolytic enzyme. The compositions facilitate trans-tympanic delivery of a therapeutic level of the moxifloxacin.
Owner:ALCON INC
Optical ear infection treatment device and method
InactiveUS8088122B2Efficient killingReduce bacterial growthSurgical instrument detailsLight therapyControl electronicsLight pipe
Optical ear infection treatment device and methods are described where an LED and optical light pipe are used to deliver the light from the LED to the middle ear of a patient to reduce bacterial growth and / or eliminate bacteria. Typically, the device is placed in the ear and then activated by the user by pressing an activation button. Once activated the control electronics will turn on the LED and perform a treatment. The most basic treatment mode comprises turning on the LED at maximum power for a predetermined period, e.g. 30 minutes, 60 minutes. When the preset duration is completed, the device will notify the user by an audible beep or vibration that the treatment is complete. Once completed the user can remove the device, the treatment could be repeated once a day or for extreme cases multiple times during the day.
Owner:CHOI GEORGE YOSEUNG
Formulation to treat ear infection
InactiveUS20080139545A1Reducing bacterial biofilmsCleanse surgical or dental instrumentAntibacterial agentsOrganic active ingredientsBacteroidesMammal
The present invention provides a pharmaceutical composition that includes: (a) at least one of a non-aminoglycoside antibiotic and an anti-inflammatory agent; and (b) a biofilm-dissolving agent. The present invention also provides for methods of killing or inhibiting the growth of a fungus by contacting the fungus with a composition of the present invention, methods of killing or inhibiting the growth of a virus by contacting the virus with a composition of the present invention, methods of killing or inhibiting the growth of a bacteria by contacting the bacteria with a composition of the present invention, methods of treating a disorder in a mammal by administering the composition of the present invention to the mammal, methods for preserving contact lens by contacting the contact lens with a composition of the present invention, methods for cleansing surgical or dental instrument by contacting the fungus with a composition of the present invention, and kits that include (a) a container that includes the pharmaceutical composition of the present invention, and (b) a drug delivery device.
Owner:CHOE WON TAEK +2
Arylamide Compounds And Compositions And Uses Thereof
The present invention discloses ophthalmic and otic compositions of facially amphiphilic antimicrobial polymers and oligomers and their uses, including their use in methods for treating and preventing ophthalmic infections and otic infections in humans and animals.
Owner:POLMEDIX INC
Treatment of ear infection using blue/violet light
ActiveUS8021405B2Effective treatmentReduce or eliminate the organism causingElectrotherapyEar treatmentViolet lightAudiology
The present invention relates to the treatment of Otitis or other type ear infections with the use of blue / violet light positioned to shine into the ear canal. The treatment quickly clears up infections and reduces the reoccurrence of ear infections.
Owner:WHITE SUSAN LEMONS
Device for measuring and analysing the colour of the outer ear and ear canal
ActiveUS20110152621A1Simple and immediate diagnosisSimplify the diagnostic processBronchoscopesLaryngoscopesOtoscopeMedicine
The present application concerns a device for measurement and analysis of the middle ear and ear channel colour for the diagnosis of ear infections. The device is composed of a otoscope (1), including two optical fibers (2a and 2b): one for ear illumination and another returning the reflected light. The electronic unit (3) can change linearly the power of emitted light, as well as, its colour. The received light is also independently measured, enabling the determination of changes on colour and texture associated with the ear inflammations. Command buttons in the otoscope handler (4) enable the user to save the values of the three colour components. The combined value of the components is shown in the digital display (5) of the electronic unit, as well as, by a set of LEDs (6) green, yellow and red that gives a diagnosis in a simple and immediate way. The otoscope allows, simultaneously, directly ear view through a magnifying glass (7) applied in the head of the otoscope, with a standard white light. This device is also useful in food industry.
Owner:UNIV DO PORTO
Inclined pulmonary-assisting mattress for infants and children
An inclined pulmonary-assisting mattress with a profile assisting infants and small children with respiratory problems and other adverse medical conditions, including asthma, wheezing, colic, SIDS, ear infections, and acid reflux. It can be used with a crib, bassinette, or other defined infant sleeping area, as long as it appropriately fills that sleeping area to eliminate all injury, entrapment, or breathing obstruction risk for the child using it. The mattress is not used on top of a crib mattress, but instead replaces a crib mattress until the child recovers or outgrows the breathing difficulty or adverse medical condition. At such time, the inclined pulmonary-assisting mattress is removed and the child is allowed to sleep on a regular crib mattress or other substantially horizontal surface. Intended applications include, but are not limited to, use in hospital neo-natal units, children's nurseries, and by parents of infants suffering from breathing or digestive issues.
Owner:STRANDBERG GUN B C +1
Combined otic and medication dispenser and method for treating otic infections
A method of treating a mammal presenting with an otic infection attributable to a pathogenic bacteria is accomplished by passing a hollow shaft having a first and second end through the tympanum of the mammal. The first end is sufficient to pierce the tympanic membrane, but flexible enough such that it buckles under the force necessary to damage any surrounding tissues in the tympanic cavity. The first end of the hollow shaft, after it pierces the tympanic membrane, extends into the tympanic cavity to aspirate a volume of effluence contained therein. The aspirated effluence is expelled out the second end of the hollow shaft. A volume of medicament (less than the volume of effluence withdrawn) is then injected through the same hollow shaft and into the tympanic cavity to treat the infection.
Owner:REED DON C +1
Bacteriophage-containing therapeutic agents
The present invention relates in its broadest aspect to combined phage / antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.
Owner:BIOCONTROL
Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections
Owner:REMPEX PHARM INC
Use of hydrolytic and oxidative enzymes to dissolve biofilm in ears
InactiveUS20100209411A1Prevent and inhibit inflammationAntibacterial agentsOrganic active ingredientsAdditive ingredientProtein molecules
A composition for removal of biofilm in the ears is useful for the treatment of ear infections such as otitis media, particularly those infections caused by Pseudomonas aeruginosa. In general, the composition comprises: (1) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the ear; and (2) a pharmaceutically acceptable carrier suitable for administration into the ear canal. The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an ear infection based on the ability of the composition to dissolve biofilm in the ear.
Owner:LACLEDE
Cyclic compounds and methods of making and using the same
The present invention provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin / low molecular weight heparin derivative.
Owner:UNIV OF MASSACHUSETTS +1
Red ear drops
InactiveUS20060057226A1Effective ear dropRelieve painBiocideOrganic active ingredientsAnesthetic AgentProtozoa
My invention, Red Ear Drops, is a combination of povidone-iodine and lidocaine hydrochloride monohydrate. The prior entity, povidone-iodine, is effective against many pathogens which include viruses, bacteria, fungi, protozoa, and yeast. The latter drug, lidocaine hydrochloride monohydrate is an effective all purpose, local anesthetic agent. The combination drug product can be an effective and safe treatment for many types of ear infections at a reasonable cost to the patient.
Owner:JOHNSON JOHN MOORE
Otic formulations, methods and devices
ActiveUS8945061B2Significant pain reliefComplications due to patients' non-complianceAntibacterial agentsBiocideTriazole antifungalsAntifungal
The present invention relates to a formulation and method for treating an ear infection, especially otomycosis and otitis externa, by administering a one-time only treatment comprising an antibiotic, and antifungal, and an anti-inflammatory in a thick, otic carrier. In one embodiment, the formulation comprises a therapeutically effective amount of active ingredients including a fluoroquinolone, a triazole antifungal, a thiocarbamate antifungal, a corticosteroid and a polyene antifungal, as well as a thickener such that the formulation, upon applying to the infected ear canal, gels and remains in the ear canal, continuously releasing the active ingredients for several days, achieving consistent complete (98-100%) clinical resolution of otomycosis and otitis externa in a single application.
Owner:METALCLAD
Treatment of ear infection using hands-free blue/violet light device
InactiveUS20090149924A1Effective treatmentEar treatmentSurgical instrument detailsLight treatmentHands free
The present invention relates to the treatment of Otis infection of the ear or other infection of the ear by application of blue violet light. The device of the present invention operates hands free mounting over the ear in such a way to provide light treatments without the need to hold the device by positioning the light source such that the light is positioned to shine into the ear canal.
Owner:WHITE SUSAN LEMONS
Otic microbial combination for treatment of animals with ruptured tympanic membrane
InactiveUS7011839B2Easy to useSimple compositionAntibacterial agentsBiocideSilver sulfadiazineTreated animal
Owner:ELANCO US INC
Composition and method for treating otitis
InactiveUS20170071979A1Promote absorptionImprove permeabilityAerosol deliveryOintment deliveryIodineDermatology
Owner:VELOCE BIOPHARMA LLC
Method of treating ear infections
ActiveUS20130243889A1Easy to removeAvoid hard activationBiocideSenses disorderExcess fluidsEustachian tube
Owner:TRY THIS FIRST INC
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