67 results about "Biopsy procedure" patented technology

A localization mechanism, or fixture, is used in conjunction with a breast coil for breast compression and for guiding a core biopsy instrument during prone biopsy procedures in both open and closed Magnetic Resonance Imaging (MRI) machines. The localization fixture includes a three-dimensional Cartesian positionable guide for supporting and orienting an MRI-compatible biopsy instrument, and in particular a sleeve, to a biopsy site of suspicious tissues or lesions. A depth stop enhances accurate insertion, and prevents over-insertion or inadvertent retraction of the sleeve. The sleeve receives a probe of the MRI-compatible biopsy instrument and may contain various features to enhance its imagability, to enhance vacuum and pressure assist therethrough, and marker deployment etc.

A biopsy device having a cutting element is disclosed. The cutting element includes an inner cannula having a tissue receiving aperture disposed proximate a distal end thereof and an inner lumen. The inner cannula is slidably disposed within the inner lumen of an outer cannula. A vacuum chamber is disposed about at least a portion of the cutting element and is configured to create a vacuum in the cutting element during a biopsy procedure. The inner cannula is advanced distally outwardly and to cause the vacuum to be generated in the vacuum chamber. The vacuum is delivered to the cutting element whereby tissue is drawn into the tissue receiving aperture. The outer cannula is advanced distally outwardly after the inner cannula such that tissue drawn into the tissue cutting aperture is severed.

A biopsy guidance device is enclosed based on a tactile imaging probe adapted to accept a biopsy gun. The tactile imaging probe includes a pressure sensing surface providing real-time 2-D images of the underlying tissue structures allowing to detect a lesion. A cannula is provided supported at a center point by a ball and socket joint. The joint is equipped with linear and angular sensors and supports the cannula with the ability to rotate thereof about the center point. The position, linear and angular displacement and direction of the needle tip of a biopsy needle placed inside the cannula is therefore known at all times and provided as a feedback signal to a physician. Also provided to a physician is a position of the target site at a lesion, as well as a linear and angular deviation of the needle tip away from the target site. Such audio, light, or visual feedback allows the physician to correct the insertion angle and depth to confidently reach the target site to perform a biopsy. Method is also disclosed to guide the biopsy procedure.

Embodiments of a needle biopsy device having a rotating needle mechanism to automatically cut sample tissue that can be operated remotely. A portable small biopsy robot can improve biopsy accuracy, reduce the pain and complications, and shorten the duration of the total biopsy time by using an automatic needle rotating mechanism and a needle localization system that allows a medical practitioner to perform the biopsy procedure from a remote distance. The needle biopsy device can include a cannula and a rotational biopsy needle with a blade the rotational biopsy needle axially and rotatably moveable within the cannula lumen, the blade configured to remove, cut, and / or separate a tissue sample from the target tissue site through rotation of the blade, and to hold the tissue sample in the rotational biopsy needle during proximal retraction from the patient.

A vibration assisted needle device is disclosed for use in medical procedures such as needle aspiration biopsies. Reciprocation of the needle, such as a biopsy needle, eases the advance of the needle through tissue, penetration of the site of interest and the collection of sample at a site of interest. The device comprises a housing defining a chamber, a needle support external to the chamber for supporting a needle and a mechanism in the chamber for causing reciprocatory motion of the needle support. The needle support is preferably external to the housing. A syringe support may be connected to the housing for supporting a syringe. The reciprocatory mechanism may comprise means for converting rotational motion into reciprocating motion, such as a bearing or a rotor with a circumferential, angled groove on its surface, coupled to the needle support. The bearing or the rotor may be driven by a rotational motor, preferably located outside of the housing, or by a hydraulically driven turbine within the housing. Alternatively, the reciprocatory mechanism means may comprise a stationary solenoid and a movable solenoid for being coupled to the needle. Preferably, a second stationary solenoid is provided and the moving solenoid is between the two stationary solenoids. Energization of the stationary solenoid or solenoids by an alternating current for example, and energization of the movable solenoid by a direct current, or vice versa, attracts and repulses the movable solenoid, causing reciprocation of the needle. Methods and systems using the vibration assisted needle device are also disclosed.

A bioabsorbable sealant plug that expands in response to contact with moisture in a mammalian body is optimally positioned in a biopsy tract to seal the biopsy tract when a biopsy procedure is completed. In a first method, the leading end of the sealant plug is advanced through the lumen of a coaxial needle by a plunger until a leading end of a supporting leg abuts the patient's skin surface. A second method is performed with a pistol-shaped tool having a trigger that enables adjustment of the plunger. A third embodiment includes a plunger having a bifurcated end that grasps the plug. A fourth embodiment has a turning nut that causes compression of a gasket that clamps down on the plug. A supporting rod and coaxial needle are in parallel relation to one another in a fifth embodiment.

A skin biopsy system covers all aspects of the biopsy procedure from initial incision to final closure. The system includes a flexible closure consisting of 4 elongated rigid members interconnected by flexible hinges. The opening within the closure is initially diamond-shaped, approximating an ellipse, which is then deformed or pinched to a narrow linear opening when the wound is closed. Included with the system is a knife which interacts with the closure to yield a guided incision of constant depth. The path of the knife is guided by interference between the blade and the inside faces of the closure while the depth is limited by interference of the handle proximal the blade and the top faces of the closure.

A system and method (i.e, utility) are disclosed for positioning a needle in three-dimensions based on patient related statistics for extracting tissue during biopsy procedures. Aspects of the utility can be applied independently or serve as an aid to the urologist when regions of interest are hard to discern in an ultrasound image. Regions of interest that correspond to high cancer risk regions (e.g., statistically) are automatically superimposed on an ultrasound image of a patient in real time. Additionally a statistical map based on one or more demographic parameters of a patient and containing cancer probability locations are also automatically mapped on the ultrasound image in real time displaying potential cancer locations. Aspects of the system are also capable of displaying optimal needle placement positions based on statistical priors and will be able to accurately navigate the needle to that position for biopsy extraction and / or treatment.

Disclosed are a barb-wired single crystalline silicon micro needle and a biopsy method and a medicine injecting method using the same. The micro needle comprises a main body part, at least one extension part formed on a side surface of the main body part, and a protrusion part protruded from both side surfaces of the extension part. A medicine storage is formed on a surface of the main body part. A fluid passage is formed in the extension part and the main body part. It is easy to pick the tissue sample with the protrusion part just by inserting and extracting the extension part of the micro needle into and from the tissue for a biopsy. Therefore, the biopsy procedures can be simplified. In addition, the medicine in the storage can be injected into the tissue via the fluid passage.

An arrangement for sinus evacuation and for taking a sample of bone marrow during a bone marrow aspiration procedure as well as a bone marrow biopsy procedure. By applying a longitudinal movement to the needle when the needle is penetrating the bone the penetration force is reduced which lower the risk of penetrating the posterior cortex or the second sinus wall. The arrangement further includes a stopping element that prevents the needle to penetrate deeper than to a predetermined depth. The arrangement further includes longitudinal movement a stopping element that provides for an active break of the longitudinal movement of the needle when the needle has penetrated down to the predetermined depth.

Biopsy of the prostate using 2D transrectal ultrasound (TRUS) guidance is the current gold standard for diagnosis of prostate cancer; however, the current procedure is limited by using 2D biopsy tools to target 3D biopsy locations. We have discovered a technique for patient-specific 3D prostate model reconstruction from a sparse collection of non-parallel 2D TRUS biopsy images. Our method can be easily integrated with current TRUS biopsy equipment and could be incorporated into current clinical biopsy procedures for needle guidance without the need for expensive hardware additions. We have demonstrated the model reconstruction technique using simulated biopsy images from 3D TRUS prostate images of 10 biopsy patients. This technique of model reconstruction is not limited to the prostate, but can be applied to the reconstruction of any tissue acquired with non-parallel 2-dimensional ultrasound images.

A compression assembly for retaining a patient's breast during a biopsy procedure that provides a wide variety of potential access points through which tissue may be accessed by a biopsy device.

An adjustable coaxial needle assembly for placement into a tissue mass prior to a biopsy procedure comprises a guide cannula assembly, a stylet, and a throw calibrator. The stylet is selectively coaxially received by the guide cannula, which is in turn coaxially received by the throw calibrator. The effective length of the guide cannula can be selectively adjusted by moving the throw calibrator relative to the guide cannula to adjust the distance between an open distal end of the guide cannula and a the throw calibrator.

Tissue biopsy is performed through a central passage of a cannula covered with a protective sleeve. The protective sleeve is attached at one end to a location at or near a distal end of the cannula. After the biopsy procedure is completed, the cannula is withdrawn so that its exterior slides through the sleeve. In this way, the trailing edge of the sleeve is invaginated within the proximal portions of the itself to envelop the sleeve exterior and reduce the risk of inadvertent tumor cell seeding.

A system and method for molecular breast imaging (MBI) provides enhanced tumor analysis and, optionally, a real-time biopsy guidance. The system includes a detector head including a gamma ray detector and a collimator. The collimator include multiple collimation sections having respectively different spatially-oriented structures. In addition or alternatively, the multiple collimating section have respectively different collimation characteristics. An image of the tissue acquired with the system may include spatially separate image portions containing image information about the same portion of the imaged tissue. A system is optionally configured to acquire updatable images to provide real-time feedback about the biopsy procedure.

A tilted needle biopsy assembly is provided for mounting on an x-ray system. Because the biopsy needle is angied relative to at least one of the detector and the x-ray source, x-ray imaging may be performed during the biopsy procedure without interference by the biopsy device. The angled biopsy needle additionally allows improved access to the axilla and chest wall of the patient. The stereotactic biopsy device of the present invention may be coupled to any x-ray system, whether upright or prone, including but not limited to mammography systems, tomosynthesis systems, and combination mammography / tomosynthesis systems. The system flexibly supports the use of any mode of image capture (i.e., scout, two dimensional mammogram, three-dimensional reconstructed volume) for either or both target visualization and target localization. With such an arrangement, a needle biopsy assembly having improved patient coverage is provided for use with a variety of different x-ray imaging platforms.

The instant invention describes a biopsy instrument which is useful in removal of tissue or fluid samples from a body, such as bone and soft tissue biopsy procedures. The biopsy instrument is an improvement over other biopsy needles currently in use in that the biopsy instrument according to the instant invention can be used to reduce the pain associated with specimen removal procedures. The biopsy instrument generally comprises an outer cannula and an inner medical probe member. The inner medical probe member is constructed and arranged to contain one or more fluid dispensing members for dispensing a fluid which are in fluid communication with a fluid dispensing device. In this arrangement, the user has the ability to continually inject fluids, such as anesthetizing agents, directly at or near the spot of specimen removal, without the need to remove the surgical instrument or use a separate fluid injecting needle.

Biopsy of the prostate using 2D transrectal ultrasound (TRUS) guidance is the current gold standard for diagnosis of prostate cancer; however, the current procedure is limited by using 2D biopsy tools to target 3D biopsy locations. We have discovered a technique for patient-specific 3D prostate model reconstruction from a sparse collection of non-parallel 2D TRUS biopsy images. Our method can be easily integrated with current TRUS biopsy equipment and could be incorporated into current clinical biopsy procedures for needle guidance without the need for expensive hardware additions. We have demonstrated the model reconstruction technique using simulated biopsy images from 3D TRUS prostate images of 10 biopsy patients. This technique of model reconstruction is not limited to the prostate, but can be applied to the reconstruction of any tissue acquired with non-parallel 2-dimensional ultrasound images.

A compression assembly is operable to localize a patient's breast. The compression assembly comprises a frame and a plurality of slats. The frame defines a plurality of tracks. The frame is configured to engage a breast localization fixture. The slats are coupled with the frame. Portions of the slats are disposed in the tracks. One or more of the slats are movable relative to the frame to provide adjustable access to a patient's breast engaged by the compression assembly. The slats may be slid and / or rotated relative to the frame. In some versions, the tracks and slats are provided in two sets. Each set lies along a respective plane, with the two planes being parallel to each other. The slats of one set may ratchetingly engage the slats of the other set to restrain slat movement. In some versions, the slats are removable from the frame for increased access.

A biopsy device includes a housing and at least one biopsy mechanism moveably connected to the housing. The biopsy can be provided on a biopsy arm. An actuator moves the biopsy arm and operates the biopsy mechanism. The biopsy arms with the biopsy mechanisms are preferably removable from the housing, such that the housing can be used again for subsequent biopsy procedures.

An angle guidance device includes a base, which can be flexible and self-adhesive; a connector piece, including a rotatable connection, which is tiltable to a left or right side, and right and left connector plates, each including center and protractor cutouts; and a guidance piece, including an insert or protractor piece, and v-shaped needle guide, such that the v-shaped needle guide can be adjusted to a predetermined device inclination angle relative to the base. Optionally included are longitudinal and lateral level components, a bullseye level, a laser pointer, a screen, and an angle-guidance control unit, including a processor, a non-transitory memory, an input / output, a CT controller, an angle sensor, an angle viewer, a 3-axis accelerometer, and a data bus. Also disclosed is an angle-guidance method, including obtaining CT images, measuring angle and depth, setting biopsy angle, marking entry point, positioning angle-guidance device, marking position, inserting procedure needle.

Disclosed herein is a system for placing an elongated permanent magnet into a volume of tissue within a human body, including placement following a large core needle tissue biopsy procedure, where the tissue is suspected of being cancerous. The magnet's position is then detected by a magnet locating system that is used by a surgeon to find and remove the suspected tissue volume including a margin of tissue to assure that any and all cancer cells have been excised.

A permanent or temporary marker is embedded within a hydrogel plug used in a biopsy procedure to indicate the location of a suspicious lesion so that the marker may be found in a subsequent surgical procedure. A combination of at least one permanent and at least one temporary marker may be used. Inserts of differing sizes and shapes may also be placed into the hydrogel plugs during their manufacturing process and removed from the plugs after the plugs have cured so that air-filled cavities are left in the plug. These cavities are temporary but may be used to augment location of a permanent marker.