The invention discloses an air purification device. The air purification device comprises a machine shell, a motor, a wind wheel, an air filter net assembly and an electric control system. The motor, the wind wheel, the air filter net assembly and the electric control system are all arranged in the machine shell. The air purification device is characterized in that the machine shell comprises a first side face and a second side face corresponding to the first side face, the first side face is provided with a first air outlet, the second side face is provided with a second air outlet, the wind wheel is arranged between the first air outlet and the second air outlet, a first air flue is formed between the wind wheel and the first air outlet, and a second air flue is formed between the wind wheel and the second air outlet. According to the air purification device, due to the fact that the double air flues are formed inside and the two air outlets are oppositely formed in the two sides, air circulation is facilitated, the efficiency of the air purification device is greatly improved, and power consumption and noise are reduced; and meanwhile the two air outlets are formed in the two sides of the machine shell, accumulated dust pollution is not likely to be caused in the two air outlet flues, and therefore the cleaning and maintaining cost of products is reduced.