54 results about "Mammalian toxicity" patented technology

The invention relates to a pesticide composition containing indoxacarb, mainly used in crops disinfestation, which comprises emulsifiable concentrate, wettable powder and suspension agent. The active ingredients of the pesticide composition are indoxacarb and active ingredient B which is any one or composition of more than one with any proportion of Methylamino abamectin benzoate, hexaflumuron, nitenpyram, avermectin, fipronil, chlorfenapyr, acetamiprid, profenofos, phoxim, high-efficiency cypermethrin, cyhalothrin, triazophos and chlorpyrifos. The pesticide composition has the advantages of enlarging the application range, having strong contact toxicity and stomach poisoning action, having low mammalian toxicity and better compatibility of environment, being effective to the pest of every growth period, increasing the effect of every component of the composition significantly, reducing the production cost and agricultural cost of the pesticide, having wide insecticidal spectrum and high efficiency, delaying the occurrence of the drug resistance of the pests, prolonging the service life of the pesticide agent, enabling the high yield and high quality of the crops, having strong activity, long persistent period and stable drug efficacy to the pests.

The invention discloses a pesticide of castor oil group, comprising castor oil, raw pesticide, emulsifier, solvent and assistant in complex formulation, which is characterized in that as the main pesticide material and carrier, castor oil is produced into a series of pesticide of castor oil pesticide group of different classes and purposes by selective compatibility and preparation of the castor oil itself or with raw pesticide of different classes. The pesticide of castor oil group has the advantages of overcoming the deficiency of harm to human and livestock, environment pollution, limited resource and high price of the prior pesticide products, having abundant sources, low price, safety, broad spectrum, high efficiency, low mammalian toxicity, low residue and non-pollution.

The invention discloses a vegetable oil based insecticidal acaricide, which comprises (by weight percent) gum spirit of turpentine 5-75%, wintergreen oil 0-55%, elliptone 0.01-5%, and balancing adjuvant.

The invention discloses a preparation method of crystal II-shaped branched chain ammonium polyphosphate, which comprises the following steps: selecting refined phosphoric acid as main raw material, as well as carbamide, trimeric cyanamide, melam, melem or a mixture thereof as a condensing agent; reacting for half an hour at the temperature of 150 to 320 DEG C; introducing ammonia; and obtaining the crystal II-shaped branched chain ammonium polyphosphate after the ammonia is aminated, cured, crystallized and crushed. The product the apparent viscosity which is greatly larger than that of the prior industrial product with the average polymerization degree up to 1000 and the thermal decomposition temperature which is larger than 300 DEG C, and can be used as a flame retardant with high efficiency, low mammalian toxicity and non-drip. The invention has the advantages of simplicity, good reliability and high accuracy rate.

The invention provides a modification method of polymer amino acid, in particular to a macromolecular compound of non-viral gene vector material, which is characterized in that the polymer amino acid is generated by polycondensation of amino acid monomer, the ring-opening of the polymer amino acid side group is processed by amino alcohol reagent, the structure modification is processed by the connection reagent, the polyethyleneimine (PEI) is joined by the activation of active hydroxy on the amino alcohol, and that the functional composite material of polymer amino acid-amino alcohol-polyethyleneimine is generated by dialysis and lyophilization. The modification method of polymer amino acid has the advantages of low mammalian toxicity, high gene transfection efficiency and performance of biodegradation.

The invention relates to a bactericidal composition containing prothioconazole and trifloxystrobin, and the bactericidal composition consists of active components and pesticide preparations as auxiliary components; and especially, the active components consist of prothioconazole and trifloxystrobin in a weight proportion of (0.2-20):1. In the invention, the prothioconazole and the trifloxystrobin are compounded in a special proportion, so that a very significant synergistic interaction effect is obtained. A mass of experiments show that the toxicity to mammals is not increased after the prothioconazole and the trifloxystrobin are compounded. Furthermore, the applicant further discovers that the bactericidal composition containing prothioconazole and trifloxystrobin can be used for further promoting the compounding effect of the prothioconazole and the trifloxystrobin with the adoption of a special wetting dispersant and a dispersion wetting agent, so that both the prothioconazole and the trifloxystrobin play a synergistic role to a maximum extent.

An assemblage composed of prochloraz-manganese and copper fungicide is provided, which is a pesticide with the weight ratio as follows: 1 per cent to 40 per cent of prochloraz-manganese, 5 per cent to 70 per cent of copper fungicide, 10 per cent to 30 of per cent of auxiliary agent and 10 per cent to 70 per cent of carrier. The invention can overcome the problems of proliferation and rampancy of acarid caused by continuously utilization of copper fungicide in long term, which is a good antiseptic featuring high efficient, abroad publication, low mammalian toxicity and environmental protection.

The invention discloses a method for preparing and using a vegetable insecticide. A supercritical CO2 liquid is utilized to extract and prepare active ingredient A agent for vegetable insecticide and a dipping method is utilized to prepare an active ingredient B agent for vegetable insecticide. The A agent and the B agent form the vegetable insecticide which is applied to control crop pests. The invention has the advantages that : 1, the invention has easily acquired materials, low mammalian toxicity, security and economy and no waste water and gas generated in the whole preparing technique flow, and the waste slag can be mixed with other fertilizers to be retted into a compound fertilizer; 2, the invention has simple preparing technique, thus being beneficial to industrial production; 3, the invention consists of various effective active insecticidal ingredients and the ingredients lead the pests hard to adapt and generate drug fastness and the drug effect is remarkable through field test; 4,the insecticide acquired by the invention can be matched with chemical pesticides for use according to a certain proportion and the drug effect is remarkably improved; 5, the insecticide acquired by the invention is stable and the effective usage period can be 2 years.

The invention provides a compound bird repelling agent containing cinnamonitrile and methyl anthranilate. A formula of the compound bird repelling agent contains the active ingredient cinnamonitrile and the methyl anthranilate, and the mass ratio of the cinnamonitrile to the methyl anthranilate is 1: 0.1-1:8.35. The compound bird repelling agent has a quite good repelling effect on birds, an obvious synergism function exists between two types of medicament, the compound bird repelling agent does not have direct killing efficiency for birds, toxicity to human beings and other mammals is low, the lasting period is long, the compound bird repelling agent is safe to crops, and harm to field crops, orchards and the like of the birds can be effectively reduced.

The invention discloses a preparation for producing a COVID-19 antibody after oral administration and a preparation method of the preparation. Attenuated salmonella typhimurium is used as a carrier todeliver DNA vaccine, the preparation effectively reaches intestinal tract and delivers DNA vaccine to intestinal endothelial cells with low mammalian toxicity infection through oral enteric-coated capsules, bacteria is phagocytosed through macrophages, and specific molecules COVID-19-S is expressed to be recognized by immune cells, so that the immune effect of specific antibodies in mammals (mice, humans and other mammals) neutralizing COVID-19-S protein is achieved.

The invention provides a high-efficiency and low-toxicity composite bird repellent containing thiram and dimethyl phthalate. The composite bird repellent contains active components of thiram and dimethyl phthalate, wherein the mass ratio of the thiram to the dimethyl phthalate is (4: 1)-(1: 20). The composite bird repellent has a very good bird repelling effect; and the thiram and the dimethyl phthalate have an obvious synergistic effect, have no direct bird killing capability and have low toxicity to humans and other mammals, so that the composite bird repellent is long in lasting effect and safe to crops, and can effectively reduce damage of birds to field crops, orchards and the like.

The invention relates to a ternary compound bactericidal composition and application thereof. The ternary compound bactericidal composition is composed of an active ingredient and a pesticide preparation auxiliary component, wherein the active ingredient is formed by compounding pyraclostrobin, metconazole and carbendazim together in a weight ratio of (0.05-1): (0.05-1.5): 1; and the pesticide preparation auxiliary component comprises compound sodium nitrophenolate accounting for 0.05-2% of the composition in mass percent. The ternary compound bactericidal composition is formed by compounding pyraclostrobin, metconazole and carbendazim together in a special ratio, thereby achieving very obvious synergistic interaction effect; and provided by lots of experiments, after compounding, toxicity on the mammal is not increased. Besides, the applicant further finds out the compounding effect of pyraclostrobin, metconazole and carbendazim can be further promoted in the special form of wetting dispersant and wetting dispersing agent according to the invention; and therefore, the synergistic effect of the three ingredients is developed to an utmost extent.

Improved synthetic copolypeptide antimicrobials contain cationic amino acid residues and may be based on a blocky sequence. These antimicrobials show low mammalian toxicity and may undergo directed self-assembly. The inventive synthetic copolypeptides are useful in treatment of wounds and other infections.

Pesticidal formulations of cadusafos are provided. An aqueous capsule suspension is provided, containing from about 150 to about 360 grams of cadusafos per liter of formulation and having lower mammalian toxicity than aqueous cadusafos microemulsion formulations is prepared by interfacial polymerization of a first polyfunctional compound, such as a polymethylene polyphenyl isocyanate, with a second polyfunctional compound, such as a polyfunctional amine or mixtures of polyfunctional amines, in an aqueous phase optionally containing from about 0.05 to about 0.50 xanthan gum viscosity modifier/stabilizer. A granular form of the microencapsulated cadusafos is also provided. Several such formulations and the method of their preparation are described.

The invention relates to the field of extraction and preparation of polypeptide protein, in particular to conotoxin polypeptide CTx-btg02 and a preparation method and application thereof. The conotoxin polypeptide CTx-btg02 is composed of 11 pieces of amino acid, and the complete amino acid sequence of the conotoxin polypeptide is SECCIRNFLCC. The conotoxin polypeptide CTx-btg02 is adopted as a medicine active ingredient, and is used for the field of insecticide. The conotoxin polypeptide CTx-btg02 has efficient insect resistant activity, is small in toxicity to mammals, can specifically act on insects and has important application value on development of efficient and safe biological insecticides.

The invention discloses a cucurbita insecticide and a preparation method thereof. The cucurbita insecticide comprises the following compositions in parts by mass: 20-30 parts of pericarpium granati, 18-20 parts of herba houttuyniae, 50-60 parts of cucumber vine, 8-10 parts of leaf of balsampear, 2-4 parts of herba andrographis, 60-70 parts of leaf of lemon eucalyptus, 50-70 parts of pericarpium zanthoxyli, 6-8 parts of fructus anisi stellati, 20-30 parts of pumpkin leaf, 10-20 parts of a material with a Chinese name of Gudongcao, 10-12 parts of fruit of towel gourd, and 2000-2200 parts of water. The cucurbita pepo insecticide is a plant insecticide, and is low in toxicity to mammals, safe to people and livestock during usage, and relatively small in environmental pressure.

The invention relates to a ternary compound sterilizing composition containing trifloxystrobin and application of the sterilizing composition. The ternary compound sterilizing composition comprises an active component, and auxiliary components of pesticide preparations, wherein the active component is compounded by the trifloxystrobin, prothioconazole and carbendazim according to the weight ratio of (0.1-1): (0.1-1):1. The ternary compound sterilizing composition has the advantages that since the trifloxystrobin, the prothioconazole and the carbendazim are compounded according to the specific proportion, an obvious synergistic interaction effect is obtained; and compared with a sterilizing composition subjected to two-component compounding, the ternary compound sterilizing composition has an expanded bacteriocidal spectrum and has the special effect for diseases such as leaf spot disease, downy mildew, scab and anthracnose of fruit trees, vegetables and cereal crops. In addition, proved by many experiments, the toxicity to mammals is not increased after compounding. An applicant further discovers that the compounding effect of the active component can be further enhanced by means of specific wetting dispersants and dispersing wetting agents, and the synergistic action can be played at the most extent.

The invention relates to a tebufenpyrad and azocyclotin miticide composite provided with synergy, which consists of effective active ingredients, auxiliaries and solvent or stuffing, and is characterized in that the effective active ingredients are tebufenpyrad and azocyclotin; the mixture ratio of tebufenpyrad and azocyclotin is 1:50-70:1. The advantages of the invention lie in that obvious synergy and continuous prevention and curing effect are possessed after tebufenpyrad and azocyclotin are combined; desinsection ectrum is enlarged, thus common fruit tree and cotton pests like red mites, tetranychus urticae koch and tetranychus cinnabarinus and so on can be killed; the composite has a plurality of functions of high efficiency, low mammalian toxicity, low pollution and low residue, and the like; besides, usage amount and frequencies of drugs are prominently lowered; cost is decreased; resistance to drugs of pests is retarded.