54 results about "Mammalian toxicity" patented technology

The invention relates to a pesticide composition containing indoxacarb, mainly used in crops disinfestation, which comprises emulsifiable concentrate, wettable powder and suspension agent. The active ingredients of the pesticide composition are indoxacarb and active ingredient B which is any one or composition of more than one with any proportion of Methylamino abamectin benzoate, hexaflumuron, nitenpyram, avermectin, fipronil, chlorfenapyr, acetamiprid, profenofos, phoxim, high-efficiency cypermethrin, cyhalothrin, triazophos and chlorpyrifos. The pesticide composition has the advantages of enlarging the application range, having strong contact toxicity and stomach poisoning action, having low mammalian toxicity and better compatibility of environment, being effective to the pest of every growth period, increasing the effect of every component of the composition significantly, reducing the production cost and agricultural cost of the pesticide, having wide insecticidal spectrum and high efficiency, delaying the occurrence of the drug resistance of the pests, prolonging the service life of the pesticide agent, enabling the high yield and high quality of the crops, having strong activity, long persistent period and stable drug efficacy to the pests.

The invention discloses a compound plant source disinfectant and a method for preparing the disinfectant. The disinfectant is made by the materials of cassia oil, sweetflag, sophora flavescens and eucalyptus oil of traditional Chinese medicines. The main effective components of the disinfectant are the cassia oil, the Beta-asarol and the matrine. After being extracted, the materials are matched with an accessory ingredient to be made into various missible oil, emulsion in water and other various preparations. The disinfectant has broad spectrum and excellent restraining effects on various plant pathogenicbacterias. The plant source disinfectant of the invention has the advantages of high efficiency, low mammalian toxicity; the harmful bacterias are difficult to generate drug fastness on the disinfectant. A field test shows that the control effect on the gen-seng leaf spot is better than that of 70 percent of mancozeb. The invention can be taken as an ideal and eco-friendly pesticide.

The invention discloses a pesticide of castor oil group, comprising castor oil, raw pesticide, emulsifier, solvent and assistant in complex formulation, which is characterized in that as the main pesticide material and carrier, castor oil is produced into a series of pesticide of castor oil pesticide group of different classes and purposes by selective compatibility and preparation of the castor oil itself or with raw pesticide of different classes. The pesticide of castor oil group has the advantages of overcoming the deficiency of harm to human and livestock, environment pollution, limited resource and high price of the prior pesticide products, having abundant sources, low price, safety, broad spectrum, high efficiency, low mammalian toxicity, low residue and non-pollution.

The invention relates to a preparation method for special pigment for aqueous printing ink. The method comprises the following steps of: (1), preparing diazotization liquid by a diazotization process for later use; (2), preparing coupling fluid; and (3), coupling, namely a, adding the diazotization liquid into the coupling fluid at the flow speed of 25 minutes, and controlling the pH value to be 10 and the temperature to be below 15 DEG C; b, continuing stirring for one hour and adding rosin fluid; c, reacting for 60 minutes and then adding 60 kilograms of 95 percent anhydrous calcium chloride; and d, raising the temperature to 85 DEG C after one hour, adding 40 kilograms of strontium nitrate dissolved with water with the temperature of 70 DEG C, raising the temperature to 90 DEG C, regulating the pH value to be 6 to 6.5 by using aluminum sulphate fluid, adding 7 kilograms of dissolved rosin amine, stirring for 60 minutes, and filtrating, rinsing, drying and crushing. The method has the advantages of use of aqueous solvent, simple process and low cost. Furthermore, the environmentally-friendly aqueous printing ink has low mammalian toxicity, no pollution, good flocculability, and good stability in an aqueous medium.

The invention discloses a vegetable oil based insecticidal acaricide, which comprises (by weight percent) gum spirit of turpentine 5-75%, wintergreen oil 0-55%, elliptone 0.01-5%, and balancing adjuvant.

The invention discloses a preparation method of crystal II-shaped branched chain ammonium polyphosphate, which comprises the following steps: selecting refined phosphoric acid as main raw material, as well as carbamide, trimeric cyanamide, melam, melem or a mixture thereof as a condensing agent; reacting for half an hour at the temperature of 150 to 320 DEG C; introducing ammonia; and obtaining the crystal II-shaped branched chain ammonium polyphosphate after the ammonia is aminated, cured, crystallized and crushed. The product the apparent viscosity which is greatly larger than that of the prior industrial product with the average polymerization degree up to 1000 and the thermal decomposition temperature which is larger than 300 DEG C, and can be used as a flame retardant with high efficiency, low mammalian toxicity and non-drip. The invention has the advantages of simplicity, good reliability and high accuracy rate.

The invention relates to a sterilization composition containing benzothiostrobin and epoxiconazole. The sterilization composition containing benzothiostrobin and epoxiconazole comprises active ingredients and auxiliary components of pesticide preparations, wherein the active ingredients are composed of benzothiostrobin and epoxiconazole in weigh ratio of 1: (0.1-16). The sterilization composition containing benzothiostrobin and epoxiconazole has a very remarkable synergistic effect by compounding benzothiostrobin and epoxiconazole according to a special proportion; and lots of experiments prove that after benzothiostrobin and epoxiconazole are compounded, the toxicity to mammals is not increased. In addition, the applicant further finds that the compounding effect of benzothiostrobin and epoxiconazole can be further promoted by adopting a specific dispersion wetting agent with the help of the sterilization composition, so that benzothiostrobin and epoxiconazole give play to the synergistic effect to the maximum extent.

Improved synthetic copolypeptide antimicrobials contain cationic amino acid residues and may be based on a blocky sequence. These antimicrobials show low mammalian toxicity and may undergo directed self-assembly. The inventive synthetic copolypeptides are useful in treatment of wounds and other infections.

The present invention provides a novel insecticide formulation that not only demonstrates strong insecticidal and residual activity against a variety of insects, but also exhibits low mammalian toxicity.

The invention provides a modification method of polymer amino acid, in particular to a macromolecular compound of non-viral gene vector material, which is characterized in that the polymer amino acid is generated by polycondensation of amino acid monomer, the ring-opening of the polymer amino acid side group is processed by amino alcohol reagent, the structure modification is processed by the connection reagent, the polyethyleneimine (PEI) is joined by the activation of active hydroxy on the amino alcohol, and that the functional composite material of polymer amino acid-amino alcohol-polyethyleneimine is generated by dialysis and lyophilization. The modification method of polymer amino acid has the advantages of low mammalian toxicity, high gene transfection efficiency and performance of biodegradation.

The invention relates to a bactericidal composition containing prothioconazole and trifloxystrobin, and the bactericidal composition consists of active components and pesticide preparations as auxiliary components; and especially, the active components consist of prothioconazole and trifloxystrobin in a weight proportion of (0.2-20):1. In the invention, the prothioconazole and the trifloxystrobin are compounded in a special proportion, so that a very significant synergistic interaction effect is obtained. A mass of experiments show that the toxicity to mammals is not increased after the prothioconazole and the trifloxystrobin are compounded. Furthermore, the applicant further discovers that the bactericidal composition containing prothioconazole and trifloxystrobin can be used for further promoting the compounding effect of the prothioconazole and the trifloxystrobin with the adoption of a special wetting dispersant and a dispersion wetting agent, so that both the prothioconazole and the trifloxystrobin play a synergistic role to a maximum extent.

An assemblage composed of prochloraz-manganese and copper fungicide is provided, which is a pesticide with the weight ratio as follows: 1 per cent to 40 per cent of prochloraz-manganese, 5 per cent to 70 per cent of copper fungicide, 10 per cent to 30 of per cent of auxiliary agent and 10 per cent to 70 per cent of carrier. The invention can overcome the problems of proliferation and rampancy of acarid caused by continuously utilization of copper fungicide in long term, which is a good antiseptic featuring high efficient, abroad publication, low mammalian toxicity and environmental protection.

The invention discloses a method for preparing and using a vegetable insecticide. A supercritical CO2 liquid is utilized to extract and prepare active ingredient A agent for vegetable insecticide and a dipping method is utilized to prepare an active ingredient B agent for vegetable insecticide. The A agent and the B agent form the vegetable insecticide which is applied to control crop pests. The invention has the advantages that : 1, the invention has easily acquired materials, low mammalian toxicity, security and economy and no waste water and gas generated in the whole preparing technique flow, and the waste slag can be mixed with other fertilizers to be retted into a compound fertilizer; 2, the invention has simple preparing technique, thus being beneficial to industrial production; 3, the invention consists of various effective active insecticidal ingredients and the ingredients lead the pests hard to adapt and generate drug fastness and the drug effect is remarkable through field test; 4,the insecticide acquired by the invention can be matched with chemical pesticides for use according to a certain proportion and the drug effect is remarkably improved; 5, the insecticide acquired by the invention is stable and the effective usage period can be 2 years.

The invention provides a compound bird repelling agent containing cinnamonitrile and methyl anthranilate. A formula of the compound bird repelling agent contains the active ingredient cinnamonitrile and the methyl anthranilate, and the mass ratio of the cinnamonitrile to the methyl anthranilate is 1: 0.1-1:8.35. The compound bird repelling agent has a quite good repelling effect on birds, an obvious synergism function exists between two types of medicament, the compound bird repelling agent does not have direct killing efficiency for birds, toxicity to human beings and other mammals is low, the lasting period is long, the compound bird repelling agent is safe to crops, and harm to field crops, orchards and the like of the birds can be effectively reduced.

The invention discloses a preparation for producing a COVID-19 antibody after oral administration and a preparation method of the preparation. Attenuated salmonella typhimurium is used as a carrier todeliver DNA vaccine, the preparation effectively reaches intestinal tract and delivers DNA vaccine to intestinal endothelial cells with low mammalian toxicity infection through oral enteric-coated capsules, bacteria is phagocytosed through macrophages, and specific molecules COVID-19-S is expressed to be recognized by immune cells, so that the immune effect of specific antibodies in mammals (mice, humans and other mammals) neutralizing COVID-19-S protein is achieved.

The invention provides a high-efficiency and low-toxicity composite bird repellent containing thiram and dimethyl phthalate. The composite bird repellent contains active components of thiram and dimethyl phthalate, wherein the mass ratio of the thiram to the dimethyl phthalate is (4: 1)-(1: 20). The composite bird repellent has a very good bird repelling effect; and the thiram and the dimethyl phthalate have an obvious synergistic effect, have no direct bird killing capability and have low toxicity to humans and other mammals, so that the composite bird repellent is long in lasting effect and safe to crops, and can effectively reduce damage of birds to field crops, orchards and the like.

The invention discloses a novel method for preparing selenate food protein, comprising the following steps of: dissolving food protein into solution containing selenate; adjusting the pH and then freezing and drying; heating the freezed and dried selenate-food protein mixture for 1-5 days under the condition of drying to perform selenate reaction; dialyzing, freezing and drying to obtain the selenate food protein; and the like. The invention has the advantages of safe selenate products and avoidance of environmental pollution due to no use of organic solvent during preparation; and simple process, controllable conditions, low production cost and easy realization of industrial production. The selenate food protein in the invention can be used as organic selenium supplement with high efficiency, low mammalian toxicity to be applied to food, health products or feed and can provide selenium element necessary to human bodies or animals. In addition, selenate food protein has immunity adjusting function and good oxidation resistance and antitumor activity, and has profound significance in developing anticancer drugs or cosmetic.

The invention relates to a ternary compound bactericidal composition and application thereof. The ternary compound bactericidal composition is composed of an active ingredient and a pesticide preparation auxiliary component, wherein the active ingredient is formed by compounding pyraclostrobin, metconazole and carbendazim together in a weight ratio of (0.05-1): (0.05-1.5): 1; and the pesticide preparation auxiliary component comprises compound sodium nitrophenolate accounting for 0.05-2% of the composition in mass percent. The ternary compound bactericidal composition is formed by compounding pyraclostrobin, metconazole and carbendazim together in a special ratio, thereby achieving very obvious synergistic interaction effect; and provided by lots of experiments, after compounding, toxicity on the mammal is not increased. Besides, the applicant further finds out the compounding effect of pyraclostrobin, metconazole and carbendazim can be further promoted in the special form of wetting dispersant and wetting dispersing agent according to the invention; and therefore, the synergistic effect of the three ingredients is developed to an utmost extent.

Improved synthetic copolypeptide antimicrobials contain cationic amino acid residues and may be based on a blocky sequence. These antimicrobials show low mammalian toxicity and may undergo directed self-assembly. The inventive synthetic copolypeptides are useful in treatment of wounds and other infections.

Conventional control agents against fleas parasitic on animals do not have sufficient selective toxicity and are hence not safe for the animals to which the control agents are applied. The control agents are not always satisfactory also in control effect and quick-acting properties. Intensive studies were made on the insecticidal activity of N-substituted indole compounds against fleas and on the safety thereof for mammals including pets. As a result, it was found that an N-substituted indole derivative, e.g., 1-(3-chloro-5-trifluoromethylpyridin 2-yl)-3-(dichlorofluoromethylthio)indole, 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(dichlorofluoromethylthio)-indole, or 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(trifluoromethylthio)indole, has high insecticidal activity and quick-acting properties and is lowly toxic to mammals including pets.

Pesticidal formulations of cadusafos are provided. An aqueous capsule suspension is provided, containing from about 150 to about 360 grams of cadusafos per liter of formulation and having lower mammalian toxicity than aqueous cadusafos microemulsion formulations is prepared by interfacial polymerization of a first polyfunctional compound, such as a polymethylene polyphenyl isocyanate, with a second polyfunctional compound, such as a polyfunctional amine or mixtures of polyfunctional amines, in an aqueous phase optionally containing from about 0.05 to about 0.50 xanthan gum viscosity modifier / stabilizer. A granular form of the microencapsulated cadusafos is also provided. Several such formulations and the method of their preparation are described.

The invention discloses a vegetable oil based insecticidal acaricide, which comprises (by weight percent) gum spirit of turpentine 5-75%, wintergreen oil 0-55%, elliptone 0.01-5%, and balancing adjuvant.

The invention relates to the field of extraction and preparation of polypeptide protein, in particular to conotoxin polypeptide CTx-btg02 and a preparation method and application thereof. The conotoxin polypeptide CTx-btg02 is composed of 11 pieces of amino acid, and the complete amino acid sequence of the conotoxin polypeptide is SECCIRNFLCC. The conotoxin polypeptide CTx-btg02 is adopted as a medicine active ingredient, and is used for the field of insecticide. The conotoxin polypeptide CTx-btg02 has efficient insect resistant activity, is small in toxicity to mammals, can specifically act on insects and has important application value on development of efficient and safe biological insecticides.

The invention discloses a cucurbita insecticide and a preparation method thereof. The cucurbita insecticide comprises the following compositions in parts by mass: 20-30 parts of pericarpium granati, 18-20 parts of herba houttuyniae, 50-60 parts of cucumber vine, 8-10 parts of leaf of balsampear, 2-4 parts of herba andrographis, 60-70 parts of leaf of lemon eucalyptus, 50-70 parts of pericarpium zanthoxyli, 6-8 parts of fructus anisi stellati, 20-30 parts of pumpkin leaf, 10-20 parts of a material with a Chinese name of Gudongcao, 10-12 parts of fruit of towel gourd, and 2000-2200 parts of water. The cucurbita pepo insecticide is a plant insecticide, and is low in toxicity to mammals, safe to people and livestock during usage, and relatively small in environmental pressure.

The invention relates to a sterilization composition containing benzothiostrobin and triticonazole. The sterilization composition comprises active ingredients and pesticide preparation auxiliary components, especially the active ingredients comprise the benzothiostrobin and the triticonazole according to a weight ratio of 1: (0.04-25). As the benzothiostrobin and the triticonazole are compounded according to a specific proportion, a remarkable synergistic interaction effect is obtained, and many experiments prove that the compounded sterilization composition does not increase the toxicity to mammals. The sterilization composition obtains a remarkable synergistic interaction effect due to the compounding of the benzothiostrobin and the triticonazole by a certain proportion, the control effect is better than that of a single monomer, the dosage is small but the bacteriocidal spectrum is increased, and the composition has a special effect for ring spot, powdery mildew, rust disease, rot, net blotch, downy mildew and rice blast of fruit trees, vegetables and cereal crops. Furthermore, many experiments prove that the compounded sterilization composition does not increase the toxicity to mammals, is safe for crops and environment, and is beneficial to environment sustainable development.

The invention relates to a ternary compound sterilizing composition containing trifloxystrobin and application of the sterilizing composition. The ternary compound sterilizing composition comprises an active component, and auxiliary components of pesticide preparations, wherein the active component is compounded by the trifloxystrobin, prothioconazole and carbendazim according to the weight ratio of (0.1-1): (0.1-1):1. The ternary compound sterilizing composition has the advantages that since the trifloxystrobin, the prothioconazole and the carbendazim are compounded according to the specific proportion, an obvious synergistic interaction effect is obtained; and compared with a sterilizing composition subjected to two-component compounding, the ternary compound sterilizing composition has an expanded bacteriocidal spectrum and has the special effect for diseases such as leaf spot disease, downy mildew, scab and anthracnose of fruit trees, vegetables and cereal crops. In addition, proved by many experiments, the toxicity to mammals is not increased after compounding. An applicant further discovers that the compounding effect of the active component can be further enhanced by means of specific wetting dispersants and dispersing wetting agents, and the synergistic action can be played at the most extent.

The invention relates to the field of extraction and preparation of polypeptide protein, in particular to conotoxin polypeptide CTx-btg01 and a preparation method and application thereof. The conotoxin polypeptide CTx-btg01 is composed of 17 pieces of amino acid, and the complete-length sequence of the conotoxin polypeptide is GGCCSHPACGVNHPELC. The conotoxin polypeptide CTx-btg01 is adopted as amedicine active ingredient, and is used for the field of insecticide. The conotoxin polypeptide CTx-btg01 has efficient insect resistant activity, is small in toxicity to mammals, can specifically acton insects and has important application value on development of efficient and safe biological insecticides.

The invention relates to a tebufenpyrad and azocyclotin miticide composite provided with synergy, which consists of effective active ingredients, auxiliaries and solvent or stuffing, and is characterized in that the effective active ingredients are tebufenpyrad and azocyclotin; the mixture ratio of tebufenpyrad and azocyclotin is 1:50-70:1. The advantages of the invention lie in that obvious synergy and continuous prevention and curing effect are possessed after tebufenpyrad and azocyclotin are combined; desinsection ectrum is enlarged, thus common fruit tree and cotton pests like red mites, tetranychus urticae koch and tetranychus cinnabarinus and so on can be killed; the composite has a plurality of functions of high efficiency, low mammalian toxicity, low pollution and low residue, and the like; besides, usage amount and frequencies of drugs are prominently lowered; cost is decreased; resistance to drugs of pests is retarded.