54 results about "Cardiac interventions" patented technology

One embodiment discloses a computerized method of facilitating cardiac intervention. The method may include inputting patient data and creating a computerized interactive model of a heart based on the patient data. The model may include features. The model may simulate at least one proposed cardiac intervention by adding or deleting features to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. A template and / or patient specific instrument may be created from the model to use as a guide during the cardiac intervention.

One embodiment discloses a computerized method of facilitating cardiac intervention. The method may include inputting patient data and creating a computerized interactive model of a heart based on the patient data. The model may include features. The model may simulate at least one proposed cardiac intervention by adding or deleting features to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. A template and / or patient specific instrument may be created from the model to use as a guide during the cardiac intervention.

One embodiment discloses a computerized method of facilitating cardiac intervention, comprising inputting patient data, creating a computerized interactive model of a diseased heart based on the patient data, wherein the model comprises structural elements, simulating at least one proposed cardiac intervention treatment by adding or deleting structural elements to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. Additionally, a template may be created from the model to use as a guide during the cardiac intervention.

One embodiment discloses a computerized method of facilitating cardiac intervention, comprising inputting patient data, creating a computerized interactive model of a heart based on the patient data, wherein the model comprises features, simulating at least one proposed cardiac intervention treatment by adding or deleting features to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. Additionally, a template may be created from the model to use as a guide during the cardiac intervention.

One embodiment discloses a computerized method of facilitating cardiac intervention, comprising inputting patient data, creating a computerized interactive model of a heart based on the patient data, wherein the model comprises features, simulating at least one proposed cardiac intervention treatment by adding or deleting features to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. Additionally, a template may be created from the model to use as a guide during the cardiac intervention.

One embodiment discloses a computerized method of facilitating cardiac intervention, comprising inputting patient data, creating a computerized interactive model of a heart based on the patient data, wherein the model comprises features, simulating at least one proposed cardiac intervention treatment by adding or deleting features to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. Additionally, a template may be created from the model to use as a guide during the cardiac intervention.

A method for non-rigid registration of digital 3D coronary artery models with 2D fluoroscopic images during a cardiac intervention includes providing a digitized 3D centerline representation of a coronary artery tree that comprises a set of S segments composed of QS 3D control points, globally aligning the 3D centerline to at least two 2D fluoroscopic images, and non-rigidly registering the 3D centerline to the at least two 2D fluoroscopic images by minimizing an energy functional that includes a summation of square differences between reconstructed centerline points and registered centerline points, a summation of squared 3D registration vectors, a summation of squared derivative 3D registration vectors, and a myocardial branch energy. The non-rigid registration of the 3D centerline is represented as a set of 3D translation vectors rs,q that are applied to corresponding centerline points xs,q in a coordinate system of the 3D centerline.

One embodiment discloses a computerized method of facilitating cardiac intervention, comprising inputting patient data, creating a computerized interactive model of a heart based on the patient data, wherein the model comprises features, simulating at least one proposed cardiac intervention treatment by adding or deleting features to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. Additionally, a template may be created from the model to use as a guide during the cardiac intervention.

A method of detection and compensation for respiratory motion improves the registration between a 3D pre-operation image and X-ray images acquired during a cardiac intervention. By synchronizing the X-ray images with the electrocardiogram, the disclosed method thus eliminates the motion related to the heart cycle from these images, thus isolating the contribution of the respiratory motion. From this point, an algorithm is proposed capable of attributing the motion remaining in the radiography images to respiration. The algorithm also enables this motion to be detected and compensated for in order to obtain a registration between 3D cardiac images and radiography images.

The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and / or a cardiac troponin in a sample the said subject. Also encompassed by the present invention are devices and kits for carrying out the aforementioned methods.

One embodiment discloses a computerized method of facilitating cardiac intervention, comprising inputting patient data, creating a computerized interactive model of a diseased heart based on the patient data, wherein the model comprises structural elements, simulating at least one proposed cardiac intervention treatment by adding or deleting structural elements to the model, and determining the effects of the proposed cardiac simulation upon the entire model. Simulations may be repeated to allow the user to determine an optimal cardiac intervention. Additionally, a template may be created from the model to use as a guide during the cardiac intervention.

A method and system for model based fusion pre-operative image data, such as computed tomography (CT), and intra-operative C-arm CT is disclosed. A first pericardium model is segmented in the pre-operative image data and a second pericardium model is segmented in a C-arm CT volume. A deformation field is estimated between the first pericardium model and the second pericardium model. A model of a target cardiac structure, such as a heart chamber model or an aorta model, extracted from the pre-operative image data is fused with the C-arm CT volume based on the estimated deformation field between the first pericardium model and the second pericardium model. An intelligent weighted average may be used improve the model based fusion results using models of the target cardiac structure extracted from pre-operative image data of patients other than a current patient.

The invention discloses a cardiac intervention ablation catheter, the catheter comprises more than two branch electrodes (5), a catheter trunk (6) and an operating handle (7), wherein, all the branch electrodes (5) are distributed in a shape of petals, the top end of each petal of branch electrode (5) is a metal electrode (12), the lower ends of the metal electrodes are provided with a temperature sensor (11), the metal electrodes (12) are connected with an examination and treatment instrument (4) through a metal wire and the temperature sensor (11) which are welded at the lower ends of the metal electrodes and a connection line (15) of the sensor passes through an insulation tube (14), a catheter trunk (6) and a handle (7) sequentially. the root part of the catheter trunk (6) is provided with a depth scale (19) and an angle scale (20), the invention can realize that the invention can be tightly affixed at the surgical site of the rugged part in the heart; the invention can realize the ring-shaped ablation under the appropriate three to five times of the rotation of the catheter.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

A method for non-rigid registration of digital 3D coronary artery models with 2D fluoroscopic images during a cardiac intervention includes providing a digitized 3D centerline representation of a coronary artery tree that comprises a set of S segments composed of QS 3D control points, globally aligning the 3D centerline to at least two 2D fluoroscopic images, and non-rigidly registering the 3D centerline to the at least two 2D fluoroscopic images by minimizing an energy functional that includes a summation of square differences between reconstructed centerline points and registered centerline points, a summation of squared 3D registration vectors, a summation of squared derivative 3D registration vectors, and a myocardial branch energy. The non-rigid registration of the 3D centerline is represented as a set of 3D translation vectors rs,q that are applied to corresponding centerline points xs,q in a coordinate system of the 3D centerline.

The present invention relates to a method for diagnosing myocardial infarction in a subject who suffers from acute coronary syndrome and has a cardiac troponin level which is detectable but lower than the level that is considered as being indicative for a myocardial infarction. Moreover, the present invention relates to a method for identifying a subject being susceptible to cardiac intervention, wherein the subject suffers from acute coronary syndrome and has a cardiac troponin level which is detectable but lower than a level that is considered as being indicative for a myocardial infarction. The methods of the present invention are based on the determination of H-FABP and, optionally, myoglobin in a sample of the subject and comparing the amount of H-FABP and, optionally, myoglobin to reference amounts.

A method and system for model based fusion pre-operative image data, such as computed tomography (CT), and intra-operative C-arm CT is disclosed. A first pericardium model is segmented in the pre-operative image data and a second pericardium model is segmented in a C-arm CT volume. A deformation field is estimated between the first pericardium model and the second pericardium model. A model of a target cardiac structure, such as a heart chamber model or an aorta model, extracted from the pre-operative image data is fused with the C-arm CT volume based on the estimated deformation field between the first pericardium model and the second pericardium model. An intelligent weighted average may be used improve the model based fusion results using models of the target cardiac structure extracted from pre-operative image data of patients other than a current patient.

A polygonal manipulator device for surgical interventions of the heart and other smooth organs is provided. A system implementing the device also is provided along with methods of use of the device and system. Methods of use of the device and system, such as for minimally-invasive cardiac intervention methods, are provided.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

The invention discloses a fixing and supporting device for cardiac intervention operations. The device includes an installation flat plate, a connecting rod and a damping shaft; the left and right sides inside the installation flat plate are provided with adjusting blocks, and the upper parts of the adjusting blocks are connected to lower fixing seats through welding; the adjusting blocks are fixedly installed on the left and right ends of the connecting rod; a first screw rod is in threaded connection with the inside of the connecting rod; and a first screw rod bearing is connected in an adjusting groove. The device rotates to drive the first screw rod so as to drive the connecting rod and the adjusting blocks installed on the left and right ends of the connecting rod to move, so that thelower fixing seat and an upper fixing seat can be driven to move; a first gear and a second tooth block are utilized to drive a second screw rod to rotate, and the second screw rod drives a moving rod in threaded connection to move, so that the heights of the fixing seats can be adjusted; and through the utilization of the upper fixing seat and the lower fixing seat to fix the arm of a patient, good fixing effects can be achieved, local tight binding feeling can be reduced, and the poor circulation of blood can be avoided.

The invention discloses a cardiac intervention type left ventricular electromagnetic assisting device which mainly comprises an in-vitro control device and a blood pump. The in-vitro control device isisolated from the blood pump by a skin layer and is connected with the blood pump by electromagnetic fields; the in-vitro control device is a box with a rectangular cross section, a power regulationknob, a current regulation knob, a power switch, an electromagnetic auxiliary switch and a liquid crystal display are sequentially arranged on the front surface of the outer side of the box from leftto right, and a charge hole is formed in the front surface of the outer side of the box. The cardiac intervention type left ventricular electromagnetic assisting device has the advantages that electromagnetic induction type control technologies are utilized, accordingly, wire holes do not need to be drilled under the skin of patients, infection can be prevented, and the cardiac intervention type left ventricular electromagnetic assisting device is easy to operate and can be continuously controlled and regulated for a long term; the cardiac intervention type left ventricular electromagnetic assisting device with the novel magnetic suspension axial flow type blood pump is high in control precision, magnetic field gravitation on an artificial heart can be balanced, the balance of magnetic field force on the artificial heart can be kept, the service life of the artificial heart can be prolonged, and the cardiac intervention type left ventricular electromagnetic assisting device can be clinically widely applied.

A system for the early detection and treatment of catheter-induced ischemic strokes includes a magnetic resonance system (20) and a processor (36). The magnetic resonance system includes a sequence controller for performing each of a plurality of imaging sequences and a sequence memory (32) which stores at least a magnetic resonance angiography (MRA) sequence, a diffusion-weighted imaging (DWI) sequence, and a perfusion-weighted imaging (PWI) sequence. The processor is programmed to control the magnetic resonance system to perform the steps of: performing the MRA sequence to generate a baseline MRA image; performing a catheter-tracking procedure to track a catheter; performing the DWI sequence after the catheter procedure to generate a diffusion-weighted image; performing the PWI sequence to generate a perfusion-weighted image; and combining the diffusion-weighted image and the perfusion-weighted image to generate a combined image for evaluating the ischemic stroke.

A method and system for predicting a measure of hemodynamic compromise as a result of transcatheter cardiac treatment. The method includes providing a patient-specific anatomical model representing cardiac region and an implant model representing a three-dimensional representation of a cardiac implant. The method includes virtually deploying said implant model into said patient-specific anatomical model. A deformation of the patient-specific anatomical model is calculated as a result of implant model deployment A measure of hemodynamic compromise is determined from the virtually deployed implant model and the deformed patient-specific anatomical model.

Described is a method for diagnosing whether a percutaneous cardiac intervention (PCI) in a subject suffering from a stable coronary heart disease was successful, the method comprising determining the amount of GDF-15 in a first sample of the subject which has been obtained after PCI and comparing the determined amount of GDF-15 with a reference amount of GDF-15 which is determined in a second sample of the subject suffering from a stable coronary heart disease obtained prior to PCI, whereby it is diagnosed whether PCI was successful. The invention also relates to the use of means for determining the amount of GDF-15 and, preferably, a natriuretic peptide and / or a cardiac troponin for the preparation of a diagnostic composition for diagnosing whether a PCI in a subject suffering from a stable coronary heart disease was successful.

The invention discloses a coronary artery delivery catheter, a catheter and a device for cardiac intervention treatment. Particularly, the coronary artery delivery catheter comprises a hollow pipe and a metal rod; the hollow pipe comprises a pipe body section and an oblique opening section, and the hollow pipe is used for containing a coronary artery balloon dilatation catheter or a stent delivery system; the length of the hollow pipe section ranges from 220 mm to 380 mm, the length of the oblique opening section ranges from 2 mm to 6 mm, the outer diameter of the hollow pipe ranges from 1.60 mm to 1.80 mm, the inner diameter of the hollow pipe ranges from 1.00 mm to 1.64 mm, and the effectively length of the coronary artery delivery catheter ranges from 135 cm to 165 cm; the hardness of the pipe body section gradually reduced from the rear end to the front end; an oblique opening is formed in the rear end of the oblique opening section, and the included angle formed by the oblique opening and the hollow pipe in the axial direction is alpha, wherein the alpha is larger than or equal to 20 degrees and smaller than or equal to 90 degrees; the rear end of the oblique opening and the front end of the metal rod are fixed through welding, and the hollow pipe and the metal rod form a fixed whole body. The coronary artery delivery catheter can be used together with a guiding catheter, lengthens the guiding catheter and delivers the coronary artery balloon dilatation catheter, a stent and the like to the more distal position of the coronary artery and position closer to a diseased region.

Provided is a catheter vibration control method of a cardiac intervention type magnetic navigation system. The method includes the following control strategies that a track suitable for a catheter (1) to follow after the catheter (1) changes the posture is found out according to an angular difference value between a current posture and a next target posture of the catheter (1), and the catheter (1) is made to be always in a posture controllable state in the posture changing process; in the two-dimensional plane, the current posture phi1 of the end of the catheter (1) is measured through a three-dimensional cardiac mapping system, a next position posture phi2 and a following step size delta phi of the catheter (1) are determined according to the operation requirements, and therefore an any-time posture phit(n) of the catheter (1) from the current posture phi1 to the next position posture phi2 is determined; in the three-dimensional spherical coordinate space, the current posture (phi1, theta1) of the end of the catheter (1) is measured through the three-dimensional cardiac mapping system, a next position posture (phi2, theta2) and following step sizes delta phi and delta theta of the catheter (1) are determined according the operation requirements, and therefore an any-time posture (phit(n), thetat(m)) of the catheter between the current posture (phi1, theta1) and the next position posture (phi2, theta2) can be determined.