The invention discloses an orthopaedic internal fixation withdrawal instrument: manual, electric, positive, reversed and calibrated trephine, which is composed of an electric trephine, a handle connecting rod (1) and a sleeve (3), wherein the sleeve includes calibrations thereon, the connecting rod is skid-proof in a triangular shape and is provided with a locking opening (2) which achieves locking by means of the connection with a steel ball portion of the handle, the jagged lower part of the sleeve (3) consists of four modes including ultrathin micro invasion, thickened anti-clamping tooth, positive and reversal, the handle is composed of a grip (4) and a locking cylinder (5), the locking cylinder (5) is internally provided with a locking steel ball (6), a pressing piece (7) and a spring (8), the pressing piece (7) presses the steel ball (6) into a steel ball slot (9) while locking so as to fix the locking port of the connecting rod of the trephine and further realize locking, and the pressing piece (7) slides downwards while unlocking so that the steel ball (6) can be bounced out of the steel ball slot along with the pressure inside the cylinder to realize decompression; the trephine has the advantages of good safety, small invasion, multiple purposes in one handle, locking, fast replacement and the like.