A balloon fatigue testing device consists of a machine base (1), a balloon infusion pump (2.1), a balloon expansion pump (2.2), a hose (3), a three-way (4), a three-way valve (5.1) and ( 5.2), special connectors (6.1) and (6.2), electric pusher (8), Luer connector (9), pin shaft (10), front support (11), rear support (12), double-ended screw Column (13), limit column (14), upper connection block (15), pressure plate (16), pump backing plate (17), valve seat (18), lower connection block (19), intelligent pressure controller (20 ) and standard parts (21-26); the electric push device (8) pushes the piston rod of the balloon dilation pump (2.2) to reciprocate, so as to realize the fatigue test of a balloon catheter delivery system (7).