35 results about "Auditory brainstem response" patented technology

An electrophysiological measurement method and system is provided for positioning an implantable transducer of a hearing instrument relative to a middle ear component or inner ear of a patient. The method and system employ electrophysiological measurement signals obtained in response to test signals applied to an implanted transducer. In one embodiment, the electrophysiological measurements are obtained by an electrocochleography measurement device that measures the cochlear summating potential and / or action potential responsive to test signals applied to an implanted transducer. In another embodiment, an auditory brainstem response measurement device is utilized to obtain electrical potential measurement signals responsive to test signals applied to an implanted transducer.

Certain examples provide a method of collecting and analyzing complex auditory brainstem response. The example method includes presenting at least one complex auditory stimulus to a subject and acquiring the subject's complex auditory brainstem response. The example method includes averaging complex auditory brainstem responses from the subject in at least one of a time domain and a frequency domain to form a collected response. The example method includes analyzing the collected response using a signal processor to process the collected response to provide a processed output and to adapt the response for comparison to the at least one complex auditory stimulus. The example method includes performing statistical computations on the processed output to generate visual and data feedback for a user.

A handheld apparatus and method for comprehensive hearing testing with pass / refer results applicable for large scale neonatal screening, adult screening, or full hearing diagnostic. The apparatus contains a signal processor, integral ear probe, and remote ear and scalp probes all packaged as a single handheld battery operated device. The apparatus preferably performs a range of tests, either independently or combined: otoacoustic measurements utilizing a novel digital signal processing method for evoked otoacoustic signal processing, auditory brain stem response test, tympanometry, and otoreflectance. Algorithms for automatic test sequence, and pass / refer indication for the tests are provided.

An apparatus and method for evaluation of hearing loss is disclosed. The apparatus and method use evoked Auditory Brainstem Responses (ABR) to determine if the subject is able to hear repeatedly administered click stimuli. In order to optimize evaluation, the present invention uses normative data to accurately weight the auditory responses, so that evaluation will be possible in different or changing noise conditions.

A method and apparatus for utilizing the benefits of encoded signal transmission and reception to enhance the performance of medical testing devices (100) adapted to evoke and measure biological response signals such as auditory evoked potentials (AEP), and the auditory brainstem response (ABR) signals in particular. Auditory stimuli, such as clicks, are presented to the ear of a human patient, in a predetermined encoded sequence, resulting in the generation of auditory responses and bio-electric response signals in the human patient. These response signals from the patient are acquired and observed, and are processed according to the predetermined encoded sequence in which the auditory stimuli were presented to the patient's ear in order to extract the desired auditory evoked potential signals or ABR signals.

A technique for determining one or more equalization parameters includes acquiring, via one or more electrodes, auditory brainstem response (ABR) data associated with a first audio sample and determining, via a processor, one or more equalization parameters based on the ABR data. The technique further includes reproducing a second audio sample based on the one or more equalization parameters, acquiring, via the one or more electrodes, complex auditory brainstem response (cABR) data associated with the second audio sample, and comparing, via the processor, the cABR data to at least one representation of the second audio sample to determine at least one measure of similarity. The technique further includes modifying the one or more equalization parameters based on the at least one measure of similarity.

A method of measuring electrically evoked auditory brainstem responses of a patient or animal body is provided. The method includes surgically implanting an auditory prosthesis having an electrode array, the electrode array positioned either intracochlear or substantially proximate a brainstem of the body. At least one electrode is stimulated in the electrode array. Electrically evoked auditory brainstem responses resulting from said stimulation are recorded using, at least in part, an electrode in the electrode array as a negative electrode, and a positive electrode positioned substantially proximate the vertex of the head of the body.

A method of measuring electrically evoked auditory brainstem responses of a patient or animal body is provided. The method includes surgically implanting an auditory prosthesis having an electrode array, the electrode array positioned either intracochlear or substantially proximate a brainstem of the body. At least one electrode is stimulated in the electrode array. Electrically evoked auditory brainstem responses resulting from said stimulation are recorded using, at least in part, an electrode in the electrode array as a negative electrode, and a positive electrode positioned substantially proximate the vertex of the head of the body.

An auditory brainstem response automatic test method based on an adaptive averaging method. With regard to auditory brainstem response single records collected in batches under various test sound intensities from high to low, on the basis of calculation performed using an adaptive averaging method, the average number of records is increased gradually by means of iteration, and a signal-to-noise ratio is increased until an auditory brainstem response signal detection condition is met, the condition involving obtaining two groups of average curves by means of auditory brainstem response single records collected in groups and in batches, calculating a time lag where the maximum value of a cross-correlation function of the two groups of average curves is located, and determining, according to whether the deviation of the time lag is within a specified range, whether there is an auditory brainstem response signal with a time locking characteristic. A hearing threshold value is obtained by means of the minimum sound intensity required for detecting a signal; or an accurate sound intensity corresponding to the hearing threshold value is obtained by performing function fitting on the number of iterations used in each test sound intensity and by means of an interpolation method. The method has a high efficiency in detecting a threshold value, has an accuracy close to that of manual determination, is more objective, has a better repeatability, and can effectively reduce the number of times that an auditory brainstem response record is repeatedly collected.

The present invention relates to a kind of auditory brainstem response (ABR) automatic test device, for the ABR records collected separately under multiple sound intensities, based on the calculation of the adaptive average method, the average number of records is increased by iteration, and the signal-to-noise ratio is improved until Meet the conditions for ABR signal detection: obtain the average curve based on the ABR records collected in batches by group, calculate the time lag at which the maximum value of the cross-correlation function between groups is located, and judge whether there is a time-locking characteristic according to whether the deviation of the time lag is within the specified range ABR signal. When the ABR signal is detected or the maximum number of iterations is reached and no ABR signal is detected, the iteration is terminated. The minimum sound intensity required to detect the signal is used as the hearing threshold; or, the function fitting is performed on the number of iterations used under each sound intensity, and the accurate sound intensity corresponding to the hearing threshold is obtained by interpolation. The present invention has high detection threshold efficiency, accuracy close to manual judgment, more objective and better repeatability, and can effectively reduce the number of repeated acquisitions of ABR records.

The invention provides an application of sodium butyrate for preventing noise-induced hearing loss, and belongs to the technical field of biological medicine. According to the application of sodium butyrate for preventing noise-induced hearing loss, in the noise-induced hearing loss experiment of mice models, sodium butyrate can reduce the auditory brainstem response threshold shift after noise exposure, increase the survival rate of cochlear hair cells after noise exposure, has excellent noise-induced hearing loss preventing effect on noises at multiple frequencies, especially has excellent preventative effect on noise-induced hearing loss, explosive hearing loss and other diseases, can be used for preparing drugs and / or healthcare products for preventing noise-induced hearing loss, has good research and application prospects, and can fill in the gap of drugs for preventing noise-induced hearing loss at present.