Whitening and water replenishing complex

A technology of whitening, hydrating, and compounding, applied in cosmetics, skin care preparations, cosmetic preparations, etc., to achieve the effects of improving skin nutrition, promoting blood microcirculation, and excellent tissue compatibility

Inactive Publication Date: 2014-04-09
CHENGDU DAME GREEN COMMODITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in the end, I got acne marks and scars, which did not fully achieve the ideal treatment effect, because long-term use of the effective ingredients in the curative products led to a series of skin problems such as skin thinning, sensitivity, and pigmentation.
[0003] At present, the functional raw materials added to whitening cosmetics on the market mainly include arbutin, hydroquinone, kojic acid, mercury compounds, fruit acid, retinoic acid, hormones, VC One or more of derivatives, cell growth factors, glabridin, azelaic acid and other raw materials, some whitening cosmetics containing the above raw materials have certain side effects on the skin while producing whitening effects, and some After adding safe and side-effect-free functional raw materials, the efficacy time is short and cannot be stored for a long time.
If arbutin is highly photosensitive, it is necessary to add a large amount of sunscreen to the product, which will cause skin aging; hydroquinone can easily cause local skin redness or systemic side effects, and easily cause skin cancer; kojic acid and its derivatives It is to inhibit the activity of tyrosinase, but because it is unstable and easy to change color, a large amount of antioxidants and ultraviolet absorbers need to be added to the formula system; vitamin C and its derivatives can reduce melanin and inhibit melanin synthesis, but the effect is not obvious , itself is unstable, and its use is limited; mercury compounds are toxic and harmful to human skin; fruit acid is a component that softens the cuticle and accelerates the exfoliation of the cuticle and accelerates the excretion of melanin. It has no direct whitening effect and can indirectly cooperate with whitening. The skin is highly irritating; retinoic acid has a greater impact on pregnant women; hormones can easily cause skin thinning, osteoporosis, and easy rebound; cell growth factors are added to creams, lotions, facial cleansers, sunscreens, masks, toners, eye creams, massages When used in ointment, hand cream or other cosmetics for the face, neck, hands and body, its active shelf life is short, it is difficult to achieve obvious effects, and the allergy rate is high; glabridin has poor efficacy and is extremely expensive Concentrated product, cost-effective; Azelaic acid can reduce the production or synthesis of tyrosinase, inhibit the synthesis of TRP-1, 2, but has poor solubility, poor compatibility, and strong irritation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A whitening and moisturizing compound, which consists of 0.05% sodium hyaluronate, 0.3% dipotassium glycyrrhizinate, 0.5% phenylethyl resorcinol, 1% nicotinamide, 55% 1 , 3 propylene glycol, 0.5% phenoxyethanol, 0.05% glycolic acid, 0.1% sodium bisulfite and 42.5% deionized water by mass.

[0037] The preparation method of the whitening and moisturizing compound is as follows:

[0038] (1) Take deionized water in proportion, and then heat the deionized water to 95 degrees Celsius, then carry out heat preservation and sterilization for half an hour, and cool to room temperature for later use;

[0039] (2) Dissolve phenethyl resorcinol in 1,3 propylene glycol in proportion, then add phenoxyethanol and stir evenly for later use;

[0040] (3) Weigh the following in proportion and add nicotinamide, dipotassium glycyrrhizinate, sodium bisulfite, glycolic acid, and sodium hyaluronate in sequence to sterilized deionized water and stir to dissolve until completely dissolved; ...

Embodiment 2

[0043] Whitening and moisturizing compound, composed of 0.1% sodium hyaluronate, 0.5% dipotassium glycyrrhizinate, 1% phenylethyl resorcinol, 5% nicotinamide, 60% 1,3 Propylene glycol, 0.5% phenoxyethanol, 0.05% glycolic acid, 0.1% sodium bisulfite and 32.75% deionized water by mass.

[0044] Its preparation method is consistent with that in Example 1.

Embodiment 3

[0046] Whitening and moisturizing compound, composed of 0.08% sodium hyaluronate, 0.4% dipotassium glycyrrhizinate, 0.6% phenylethyl resorcinol, 3% nicotinamide, 58% 1.3 propylene glycol, 0.5% phenoxyethanol, 0.04% glycolic acid, 0.08% sodium bisulfite and 37.3% deionized water by mass, and its preparation method is consistent with that in Example 1.

[0047] Add the whitening and moisturizing complexes of the above-mentioned 3 embodiments to the base ointment by 3%, and carry out curative effect experiments on 30 patients each, and obtain the results in the following table: As can be seen from the data in the table, the effect of whitening and removing freckles is effective. The efficiency reaches over 90%, the effective rate of anti-wrinkle and water replenishment reaches over 86%, and the skin repair rate reaches over 76%. Therefore, the present invention is a whitening compound with the functions of whitening, anti-wrinkle, moisturizing and repairing, and the patients of t...

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PUM

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Abstract

The invention belongs to the field of cosmetics, and particularly discloses a whitening and water replenishing complex. The complex comprises from 0.05 to 0.1% of sodium hyaluronate, from 0.3 to 0.5% of dipotassium glycyrrhizinate, from 0.5 to 1% of phenethyl resorcinol, from 1 to 5% of niacinamide, from 55 to 60% of tripropylene glycol, 0.5% of phenoxyethanol, from 0.02 to 0.05% of glycolic acid, from 0.05 to 0.1% of sodium bisulfite and from 32.75 to 41.58% of deionized water. The whitening and water replenishing complex is directly added into a whitening and water replenishing moisturizing product at the temperature lower than 50 DEG C and is uniformly stirred. The whitening and water replenishing complex realizes a whitening effect, and can suppress melanin secretion of melanocyte simulating cells of the surface of the skin of a user, so that the skin of the user is whitened. Besides, the whitening and water replenishing complex realizes an anti-wrinkle effect, can promote collagen and elastin secretion of fibroblasts and realizes effects of preventing ageing of the skin of the user and improving elasticity of the skin of the user.

Description

technical field [0001] The invention belongs to the field of cosmetics, in particular to a whitening and moisturizing compound. Background technique [0002] Due to age changes, changes in body functions and long-term exposure to adverse environments, especially exposure to UVA, UVB and IR radiation, the skin undergoes structural and functional changes, including loss of elasticity, wrinkle formation, loss of water holding capacity, sagging and Microcirculation disturbance, stain formation. Especially when the skin is exposed to ultraviolet rays, melanin is actively synthesized in skin melanocytes and released to the epidermis. Melanin synthesis in melanocytes is mediated by tyrosinase. Specifically, cellular tyrosine is converted by tyrosinase into dopaquinone, from which melanin is produced by a spontaneous enzymatic reaction. Therefore, the concept that melanin production can be counteracted by blocking some reactions of the melanin synthesis pathway is widely accept...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/73A61K8/67A61K8/63A61Q19/02A61Q19/00
Inventor 秦伟沈罟
Owner CHENGDU DAME GREEN COMMODITY
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