Surface modification method for medical grade silicon rubber

Abstract

The invention discloses a surface modification method for a medical grade silicon rubber. The surface modification method is an ion implantation method, the implanted ions are C ions, and the ion-implanted material to be modified is the medical grade silicon rubber; in the process of ion implantation, the ion energy is 5 to 10kev, the using amount of ions is 1.0*1,014 ions / cm<2> to 1.0*1,016 ions / cm<2>, the beam density is no more than 0.6 mA / cm<2>, and the residual gas pressure is no more than 1*10<-3>Pa; and in the surface modification method, the C ions serving as the major elements of the human body are selected as the implanted ions, so that the hydrophily of the surface of the silicon rubber, namely the affinity with an organism, is enhanced, and the silicon rubber after being implanted into the human body can be comparable with histocytes, and the deformation and displacement of a medical silicone rubber implant are avoided. Meanwhile, the surface modification method of the invention overcomes the defects of poor peeling, poor stability and complicated processing steps, and the like existing in conventional plasma treatment, graft copolymerization and bionic coating, and the like.

Description

technical field [0001] The invention relates to a modification method of medical auxiliary materials, in particular to a surface modification method of medical silicone rubber. Background technique [0002] The deformities and defects of body surface tissues and organs caused by congenital or trauma mainly rely on surgical methods for reconstruction and repair. Implantation of soft tissue filling materials in deformities and defects is the main treatment method, and it is also in line with the development trend of modern medicine to replace "wound repair with trauma" with "non-invasive repair". However, the key problem that restricts the further improvement of clinical treatment effect is: the surface of non-absorbable organic polymer materials widely used for soft tissue filling is strongly hydrophobic, resulting in poor compatibility of tissue cells, fibrous connective tissue around the material Cysts are formed, and the cysts thicken and contract over time, which can eas...

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Problems solved by technology

However, the key problem that restricts the further improvement of clinical treatment effect is: the surface of non-absorbable organic polymer materials widely used for soft tissue filling is strongly hydrophobic, resulting in poor compatibility of tissue cells, fibrous connective tissue around the material Cysts are formed, and the cysts thicken and contract over time, which can easily lead to deformation and displacement of implant materials

The graft copolymerization method activates the surface of the polymer through a chemical reaction, and then introduces a specific group. The surface group formed is unstable and the steps are cumbersome; the biomimetic coating can be sprayed, sputtered and Such methods cover a layer of biologically active substances on it, but there are also problems such as difficult control of conditions and cumbersome steps.

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