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Mastitis plaster for animals preparation and feeding method thereof

A technology for mastitis and plaster, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and ointment delivery, etc. It can solve problems such as fever, vomiting, allergies, and harm to human health.

Inactive Publication Date: 2008-12-10
HARBIN SHENGCAOTANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In recent decades, the treatment of this disease has been mainly based on antibiotics, but people have gradually realized that antibiotics cannot fundamentally solve the problem, especially the problem of bacterial resistance caused by long-term high-dose use is becoming more and more serious
Moreover, because the milk of sick cows contains a large amount of pathogenic microorganisms and their toxins or a large amount of antibiotic residues after treatment, human consumption can cause symptoms such as fever, vomiting, allergies, and endanger human health.

Method used

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  • Mastitis plaster for animals preparation and feeding method thereof
  • Mastitis plaster for animals preparation and feeding method thereof
  • Mastitis plaster for animals preparation and feeding method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] Embodiment 1, to the antipyretic action of rat-turpentine oil-induced fever method

[0089] 1.1 Drugs and reagents

[0090] The dosage of the present embodiment includes 60g of dandelion, 60g of Viola chinensis, 42g of Phellodendron officinalis, 42g of wild chrysanthemum, 42g of Prunella vulgaris, 42g of Bletilla striata, 32g of earthworm, 32g of mulberry branch, 32g of blood remaining charcoal and 32g of Zanthoxylum bungeanum, per 1g. The amount of crude drug contained in the ointment is about 0.23g. Usage and dosage: Take an appropriate amount and apply it evenly on the affected area, once every other day.

[0091] 1.2 Experimental animals

[0092] A number of New Zealand white rabbits, weighing 2.1-2.5 kg, half male and half male, were provided by Jiangbei Wanfang Experimental Animal Farm in Harbin City.

[0093] 2. Method

[0094] After a week of regular feeding and observation of the rabbits, the anal temperature was measured 1-2 times a day for 3 consecutive d...

Embodiment 2

[0100] Embodiment 2, the anti-inflammation effect to rat-small white mouse auricle swelling method

[0101] 1.1 Drugs and reagents

[0102] The dosage of the present embodiment includes 60g of dandelion, 60g of Viola chinensis, 42g of Phellodendron officinalis, 42g of wild chrysanthemum, 42g of Prunella vulgaris, 42g of Bletilla striata, 32g of earthworm, 32g of mulberry branch, 32g of blood remaining charcoal and 32g of Zanthoxylum bungeanum, per 1g. The contained crude drug amount of ointment is about 0.3g. Usage and dosage: Take an appropriate amount and apply it evenly on the affected area, once every other day.

[0103] 1.2 Experimental animals

[0104] Kunming white mice, weighing 25-30 g, half male and half male, were provided by the Experimental Animal Laboratory of the Second Affiliated Hospital of Harbin Medical University.

[0105] 1.3 Experimental equipment

[0106] Hole punch, analytical balance.

[0107] 2. Experimental method

[0108] Fifty Kunming mice we...

Embodiment 3

[0122] Embodiment 3, the analgesic effect to mouse-hot plate method

[0123] 1.1 Drugs and reagents

[0124] The dosage of the present embodiment includes 60g of dandelion, 60g of Viola chinensis, 42g of Phellodendron officinalis, 42g of wild chrysanthemum, 42g of Prunella vulgaris, 42g of Bletilla striata, 32g of earthworm, 32g of mulberry branch, 32g of blood remaining charcoal and 32g of Zanthoxylum bungeanum, per 1g. The amount of crude drug contained in the ointment is about 0.23g. Usage and dosage: Take an appropriate amount and apply it evenly on the affected area, once every other day.

[0125] 1.2 Experimental animals

[0126] Kunming white mice, weighing 18-22 g, are female, provided by the Experimental Animal Laboratory of the Second Affiliated Hospital of Harbin Medical University.

[0127] 1.3 Equipment

[0128] RCY-2 hot plate pain tester: Shanghai Yilian Science and Education Equipment Co., Ltd.

[0129] 2. Test method

[0130] Take several healthy female ...

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Abstract

The present invention provides a mastitis ointment for animals as well as a preparation method and medication thereof. The mastitis ointment is a compound preparation made from ten Chinese medicinal materials with the following weight proportion: 50 to 70g of dandelion, 50 to 70g of tokyo violet herb, 40 to 60g of cortex phellodendri amurensis, 40 to 60g of wild chrysanthemum, 40 to 60g of common selfheal, 40 to 60g of common bletilla, 30 to 50g of earthworm, 30 to 50g of mulberry branch, 30 to 50g of carbonized hair and 30 to 50g of pricklyash berry. The mastitis ointment has the efficacies of clearing toxic heat, promoting blood circulation for removing blood stasis, reducing swelling, discharging pus and removing obstruction in collaterals, which mainly cures earlier acute mastitis, red swelling and thermal pain, carbuncle-abscess and yellowish swelling; moreover, the mastitis ointment is suitable for curing breast diseases of cows, pigs and other livestock such as clinical and recessive mastitis, acromastitis and breast lump, as well as pyogenesis, empyema, breast red swelling and thermal pain, breast skin temperature increase and no latex caused by mechanical and sucking damages. The mastitis ointment based on the production technology of the traditional Chinese black plaster makes certain improvements, thus being more suitable for treatment of cow mastitis.

Description

(1) Technical field [0001] The invention relates to veterinary drug technology, in particular to a veterinary mastitis ointment. (2) Background technology [0002] Dairy cow mastitis is one of the most common diseases that endanger the dairy farming industry. It is a kind of resistant inflammatory reaction of mammary gland tissue caused by various factors. The main pathological changes are mammary gland tissue lesions, which cause lactation disorders. Mastitis caused by pathogenic microorganisms invading the mammary gland accounts for the majority, such as bacteria, viruses, mycoplasma, fungi, etc. invade the nipple, enter the mammary gland tissue through the mammary duct, and cause disease. About 94% of cow mastitis in my country is caused by Staphylococcus and Streptococcus. Cow mastitis can be divided into clinical mastitis and recessive mastitis according to whether there are clinical symptoms. It is generally believed that clinical mastitis accounts for 30% and recessi...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/06A61K47/02A61K47/44A61P15/14A61K35/36A61K35/64A61K35/62
Inventor 李云峰李凯书李晓慧李继昌
Owner HARBIN SHENGCAOTANG PHARMA
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