The invention discloses a tire structure for a wheelchair. A plurality of pattern groups are uniformly distributed at intervals on a tread of a tire in the circumferential direction, each pattern group contains an inverted S-shaped pattern block on the center line of the tread, and each inverted S-shaped pattern block comprises a central axle part and two flank parts, wherein the two correspondingflank parts are at 180 degrees from each other along the center of the tread. The central axle parts are located on the center line of the tread and are in a concave-convex shape with a wide upper end, a narrow middle end and a wide lower end in the circumferential direction of the tire. The two flank parts of the inverted S-shaped pattern blocks are arranged on one sides of the upper and lower ends of the central axle parts in an opposite mode. According to the tire structure for the wheelchair, through the structural design of the inverted S-pattern blocks on the center line of the tread, so that the inverted S-pattern blocks located at the center of the tread has double directionality, the tire can be switched smoothly between forward, backward, rotation and any other movement, the wheelchair is enabled to be labor-saving in pushing, agile and durable, a good catching performance is played, and safety hazards are reduced.