41 results about "Gynecomastia" patented technology

The present invention provides methods for treating and preventing gynecomastia by administering 4-hydroxy tamoxifen to a patient. When percutaneously administered to a patient's breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogenic effect. In patients with gynecomastia, this reduces the effective estrogen-androgen ratio in the breast tissue, thereby reducing ductal proliferation, epithelial and stromal hyperplasia, and pain. In patients at risk for developing gynecomastia, 4-hydroxy tamoxifen's anti-estrogenic effect prevents tissue proliferation and its accompanying pain.

Pharmaceutical compositions comprising 4-hydroxy tamoxifen in an amount of 0.105-0.950% by weight effectively deliver the 4-hydroxy tamoxifen. Such compositions, including gels, can treat or prevent benign breast disease, scarring or a keloid, gynecomastia, breast cancer, mastalgia, or a condition involving dense breast tissue.

The invention discloses a pill for treating gynecomastia and a preparation method thereof, and belongs to the field of traditional Chinese medicine. The pill comprises the raw materials of effective components: eucommia bark, radix dipsaci, semen cuscutae, white atractylodes rhizome, herba epimedii, fructus lycii, cortex cinnamomi, radix bupleuri, nutgrass galingale rhizome, pericarpium citri reticulatae, radix salviae miltiorrhizae, poria cocos, cortex moutan, rhizoma chuanxiong, radix paeoniae rubra, radix polygoni multiflori, rhizoma curcumae, cornua cervi pantotrichum, radix cyathulae, rhizoma alismatis, rhizoma pinellinae praeparata, tuber fleeceflower stem, bulbus fritillariae cirrhosae, licorice, pulp of cornus, and curculigo orchioides; the above medicines are processed in a certain way to prepare the pill product. The selected medicines meet the principle of different raw materials having different functions, drug properties are adapted and complemented with each other, the remedy is suited to the cases aiming at loss of nourishment of liver and kidney, blood and qi stagnation, liver qi depression and phlegm stasis, qi stagnation and blood stasis and other pathogenesis, and the pill has the effects of nourishing the liver and kidney, smoothing liver and resolving depression, and promoting blood circulation to remove meridian obstruction, has the advantages of good absorption effect, obvious curative effect, no toxic or side effect and no clinical adverse reactions, and has relatively high cure rate on gynecomastia through clinical verification.