39 results about "Female contraceptives" patented technology

The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng / ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly.

The invention discloses a female contraceptive patch. The female contraceptive patch comprises a female contraceptive condom body; an open end is arranged on the female contraceptive condom body; a contraceptive patch body integrated with the female contraceptive condom body is arranged outside the female contraceptive condom body; and adhesive sticker is arranged on the inner side of the contraceptive patch body. By the structural design, a user can conveniently wear a contraceptive device when having sexual life, so that the quality of sexual life is guaranteed.

The invention provides an application of lactobacillus crispatus in preparation of female contraceptives. According to the technical scheme, firstly, the influence of lactobacillus crispatus on spermsis studied, and experiments are conducted in an in-vitro co-incubation mode and an animal vaginal administration mode respectively; experimental results show that the lactobacillus crispatus has obvious adhesion to sperms, so that the sperm motility and swimming ability are remarkably reduced. Based on the found new properties of the lactobacillus crispatus, the new application of the lactobacillus crispatus in preparation of female contraceptives is determined. Animal experiments show that when a vaginal suppository containing the lactobacillus crispatus liquid acts on the vagina of a femalemouse, the pregnancy rate of the female mouse can be accurately reduced, and the contraceptive rate can reach about 50%. A lactobacillus crispatus bacterial suspension is safe and non-toxic, the probiotic effect of the lactobacillus crispatus bacterial suspension is combined with reproductive contraception, the limitation of a traditional contraception mode is broken through, and the lactobacillus crispatus bacterial suspension is safe, effective and reversible, can help to adjust genital tract micro-ecological balance of women and is of great significance to reproductive health of women.

A contraceptive drug delivery system is provided in the form of a controlled release, bioerodible pellet for subdermal implantation. The pellet is bioerodible, and provides for the sustained release of a contraceptive agent over an extended time period. Bioerosion products are water soluble, bioresorbed, or both, obviating the need for surgical removal of the implant. Methods of using the drug delivery system, including in female contraception, are also provided.