33 results about "Blood component separator" patented technology

A separator disk (4) for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.

A blood storage container suitable for quick and efficient production of a large amount of serum while ensuring high safety, and a method of separating blood and a regenerative medical process using the same are provided. In a blood component separator 1 for separating collected blood into a plurality of blood components and preserving them, the separator 1 including a blood reservoir 10 for reserving the blood and a component storage part 20 aseptically connected in an air-tight manner to this blood reservoir 10, to the aforementioned blood reservoir 10 being imparted a serum producing function to remove coagulation factors from the blood to an extent enabling use in practical applications as a serum, and the aforementioned component storage part 20 storing each blood component generated by separation of the blood in the blood reservoir 10.

The invention discloses a regulation and control method of a blood component separator and a blood component separator. The method comprises the following steps that: a rotary knob of an encoder rotating shaft is rotated to rotate the rotating shaft of the encoder for regulation and control, and the encoder transmits the mechanical quantity of the rotating shaft to a main control system of a blood component separator in a pulse signal mode; the main control system decodes the received pulse signals, records the number of pulse signals, detects changes of the pulse signal phases, and transmits a control instruction being information of the number of the pulse signals and the phase changes to to-be-control-parameter equipment. In addition, the invention also discloses a blood component separator using the regulation and control method. According to the technical scheme, the fast degree of parameter adjustment can be controlled autonomously by the user; the speed of the blood component separator during parameter adjustment can be accelerated effectively; and the safety risk coefficient of medical equipment during application can be reduced.

The invention discloses a blood bag plug-breaking and shaking-up device and a blood component separator. The blood bag plug-breaking and shaking-up device comprises a machine body, a plug-breaking mechanism and a shaking-up mechanism. The plug-breaking mechanism comprises a plug-breaking head installed on the machine body and a first driving mechanism in driving connection with the plug-breaking head. The first driving mechanism is used for driving the plug breaking head to move so that a blood bag plug rod can be broken. The shaking-up mechanism comprises a supporting plate installed on the upper side of the machine body and a second driving mechanism in driving connection with the supporting plate. The second driving mechanism is used for driving the supporting plate to move so that fluid in the blood bag placed on the supporting plate can be mixed. The blood bag plug-breaking and shaking-up device has the plug-breaking function and the shaking-up function at the same time, and the blood bag plug rod can be broken so that red blood cells and preserving fluid can be sufficiently mixed and the red blood cells can be prevented from being clotting; integrity is high, and the space occupied by the device is reduced. The blood component separator comprises a blood bag squeezing device, a weighing device, a heat sealing device and the blood bag plug-breaking and shaking-up device. The blood component separator has the blood component separating function, the plug-breaking function and the shaking-up function at the same time, and the aim of conducting separating over shaking-upafter plug-breaking is realized.

The invention discloses a blood component separation device, which is used for separating erythrocyte, platelet and plasma in blood. The blood component separation device comprises a first storage bag, a first filtering mechanism, a blood component separator, a second filtering mechanism, a third filtering mechanism and a second storage bag, wherein the first storage bag is used for storing blood; the first filtering mechanism is communicated with the first storage bag and is used for filtering the blood; the blood component separator is communicated with the first filtering mechanism; the second filtering mechanism is arranged in the blood component separator and is used for separating the platelet and the plasma to obtain the erythrocyte; the third filtering mechanism is arranged in the blood component separator and is used for filtering the plasma to obtain the platelet; the second storage bag is communicated with the blood component separator and is used for storing the filtered remained plasma; the third filtering mechanism is positioned under the second filtering mechanism. The invention also discloses a blood component separation method. The blood component separation method has the steps that under the gravity action, microcapsules are filtered by a microcapsule filter, leukocyte is filtered by a leukocyte filter, and the erythrocyte, the platelet and the plasma are separated by the first filter and the second filter. The device has the advantages that the cost is low, and the operation is easy.

The invention belongs to the field of devices for blood component separation, and relates to a centrifugal bag type blood component separator. The centrifugal bag type blood component separator comprises a double-layer flow path integration device, the double-layer flow path integration device communicates with an anticoagulant bag, a saline bag, a whole blood bag, a erythrocyte bag, a plasma bag, a blood platelet bag and a centrifugal bag; the double-layer flow path integration device comprises an upper cover plate, a middle integrated body and a lower cover plate, wherein the middle integrated body comprises an outer shell; the inner part of the outer shell is partitioned into an upper layer and a lower layer by a middle partition plate; an anti-coagulant pipe, a blood collection tube, a blood return tube, a centrifugal tube, a plasma tube, an erythrocyte tube, a PRP tube, a blood platelet tube, a whole blood vessel and a mixing tube are distributed on the upper layer and the lower layer; and the outer periphery of the outer shell is provided with a plurality of connectors distributed in two layers, and the connectors communicate with corresponding pipelines arranged in the upper layer and the lower layer. According to the centrifugal bag type blood component separator, the structure is simple, only one double-layer flow path integration device is needed, the number of electromagnets needing to be used in cooperation with the whole device is small, the safety is high, the damage rate is low, and the service life is long.

The invention belongs to the field of devices for blood component separation, and relates to a double-layer-flow path integration device for a centrifugal bag type blood component separator. The integration device comprises an upper cover plate, a middle integration body and a lower cover plate from top to bottom, the middle integration body comprises an outer shell, the interior of the outer shell is partitioned into an upper layer and a lower layer by a middle partition plate, anticoagulant pipes, a brine pipe, a blood collection pipe, a blood return pipe, centrifugal pipes, plasma pipes, erythrocyte pipes, PRP pipes, blood platelet pipes, a whole blood pipe and mixing pipes are distributed on the upper layer and the lower layer, a plurality of connectors distributed in a two-layer mode are arranged on the periphery of the outer shell, and the connectors communicate with corresponding pipelines arranged in the upper layer and the lower layer. The integration device has the advantages that the structural design is reasonable, the pipeline structure is simple, in actual use, the number of parts which are required to be matched with the device for use is few, the safety is high, the damage rate is low, and the service life is long; and in the circulation process of blood, air is not prone to mixture, so that the damage probability of a blood donor is reduced.

The invention discloses a combined blood component separation utensil. The utensil comprises an upper push handle, a platelet extraction tube, an extraction rod, a needle tube, an erythrocyte extraction tube and a lower push handle, the inner surface of the upper push handle is provided with a first sealing member, the platelet extraction tube comprises an upper extraction tube part and a lower extraction tube part, a fixing layer at the bottom of the upper part of the needle tube, the erythrocyte extraction tube comprises a first section, a necking section and a second section, and the opening of the first section is provided with an internal thread. Blood is centrifuged in the erythrocyte extraction tube to obtain upper plasma and lower erythrocytes, the upper plasma and lower erythrocytes are separated under the action of the lower push handle, the second sealing member and the extraction rod, the utensil is inverted, the plasma flows into the platelet extraction tube, and is centrifuged to obtain upper serum and lower platelet-rich plasma, and the platelet-rich plasma is successfully separated and extracted under the action of the first push handle, the first sealing member andthe extraction rod. The utensil achieves the purposes of simply operating the extraction process and reducing the extraction cost.

The invention discloses an automatic stopper breaking mechanism and a blood component separator. The automatic plug breaking mechanism is mounted on a side plate of a separator body to break a stopperrod of a blood bag, and comprises a driving module, a first clamping unit and a second clamping unit, wherein the first clamping unit and the second clamping unit are both provided with clamping openings for clamping the two ends of the stopper rod respectively; and the driving module is in driving connection with the first clamping unit and the second clamping unit respectively, and is used fordriving the first clamping unit and the second clamping unit to rotate back and forth relatively in opposite directions at the same time, so that the stopper rod arranged in the two clamping openingsis broken off from the middle. Two clamping units are adopted to clamp the upper end and the lower end of the stopper rod and simultaneously rotate back and forth relatively in opposite directions tobreak the stopper rod, so that compared with manual operation, the working load of an operator is reduced, and the working efficiency is improved; and compared with the technology that only a single clamping unit clamps the stopper rod to rotate back and forth to break the stopper rod, the two clamping units enable the angle range of bending of the stopper rod to be larger, the breaking success rate to be higher, and the efficiency to be higher.

The invention relates to the technical field of medical apparatuses, in particular to a pneumatic type blood collecting system which comprises a laser blood collector. The output end of the laser blood collector is connected with one end of a flow dividing pipe through a pipeline. The other end of the flow dividing pipe is connected with a mixing mechanism. The mixing mechanism is connected with the input end of a blood filter through a pipeline. The output end of the blood filter is connected with a detector. The detector is connected with a blood component separator through a pipeline. The bottom end of the right side of the blood component separator is connected with a blood component collecting container through a pipeline. The blood component collecting container is connected with anair pump through a pipeline. By using the laser blood collector, the flow dividing pipe and a standing mechanism in cooperation, the safety during blood collecting is improved; through the mixing mechanism, an anticoagulant and blood can be more evenly mixed, blood coagulation is prevented, the blood collecting stability is improved, and the stability and safety of the system are greatly improved.

The invention discloses a platelet single collection system, which is characterized by comprising a venous needle (1), a reversing valve (2), a first mixer (4), a whole blood pump (5), an accumulatingflow meter (6), a first valve (7), an anticoagulant injector (8), a second valve (10), a blood component separator (11), a platelet pump (12), a platelet collection container (13), a plasma pump (14), a second mixer (15), an other component pump (16), a return pump (18), and a third valve (19). The platelet single collection system can realize accurate and fixed-amount blood collection and accurate and fixed-amount addition of an anticoagulant to ensure that whole blood and the anticoagulant are sufficiently uniformly mixed before separation to avoid insufficient or invalid anticoagulant dose, and at the same time, blood can be taken intermittently and then returned to ensure the stability of the flow rate when returning. The invention also discloses a collection method for the platelet single collection system.

The invention discloses a blood component separator and a use method, and belongs to the technical field of blood component separators, the blood component separator comprises a shell, a placement frame and a centrifugal mechanism, the placement frame is fixed on the upper surface of the shell, the centrifugal mechanism is mounted in the shell, a blood pumping device is mounted at the top in the shell, and the blood pumping device comprises an outer arc shell and a blood pumping disc; a blood pumping motor is fixed to the upper surface of the shell, a blood pumping disc is fixed to an output shaft of the blood pumping motor, and a protruding block is arranged on the side wall of the blood pumping disc. A blood bag can be firmly specified through the containing frame, the blood bag is prevented from inclining, residues in the blood bag are reduced, a liquid inlet pipe can be prevented from being scattered through a balance weight wheel, and blood can be continuously conveyed through the blood pumping device; by matching with a moving pipe and a liquid inlet pipe, excessive contact between blood and the outside in the conveying process is avoided, sanitation is guaranteed, blood splashing is avoided, the centrifugal barrel can automatically push the layered blood upwards, then the layered blood is discharged through the infusion pump, and operation and use of a user are facilitated.

The invention discloses a pneumatic type blood collecting system, and relates to the field of medical instruments and apparatuses. The pneumatic type blood collecting system comprises a puncture needle, a three-way connector, a blood filter, an anticoagulant puncture outfit, a blood donor pressure detecting connector, a saline solution puncture outfit, a blood component separator, a blood component collecting container, a system pressure detecting connector, a system pressure detector, a pressure buffering device, an air pump and a main controller. The invention further discloses a use method of the pneumatic type blood collecting system. The defects that when blood is collected by a peristaltic pump in a peristalsis mode, blood cell rupture caused by extrusion, hemolysis caused by high temperature, pipeline rupture caused by extrusion, high blood donor blood pressure fluctuation caused by peristalsis, complicated operation and the like are easily generated can be overcome, the running reliability of the blood component collecting device can be improved, the blood collecting safety is ensured, and the comfort of a blood donor is improved.

The invention provides a cell preparation method which involves cell preparation equipment. The equipment is modified on the basis of a full-automatic blood component separator and used for cell culture and preparation, a grating is substituted by a weighing sensor, and an air inlet device and a liquid sensor are added. By optimization of a collocation relation of devices in the integral equipment, equipment operating procedures are simplified, the devices are in mutual cooperation in each step, production cost is reduced, process integration is realized, a cell preparation process is intelligent and automatic, simplicity and convenience in operation are achieved, cell contamination is reduced, the cell preparation success rate is increased, and accordingly a promising application prospectand a huge market value are achieved.

The invention discloses an exhausting method applied to an automatic blood component separator. The exhausting method is used for carrying out exhausting work on blood serum obtained by whole blood separation; the automatic blood component separator at least comprises a blood serum bag hanging arm, a front extruding plate and a heat sealing head; the exhausting method mainly comprises the following steps: manufacturing a series of blood serum bags with different weights; operating the automatic blood component separator in sequence to extrude the blood serum bags with different weights, which are suspended on the blood serum bag hanging arm, through the front extruding plate until all air in the upper part is exhausted and the blood serum in the blood serum bags is raised to a triangular connector of a triplet blood bag; checking and recording a front extruding plate movement distance corresponding to each of the blood serum bags with different weights through software of the automatic blood component separator; programming specifications and types corresponding to the blood serum bags, the weights of the blood serum bags and the front extruding plate movement distances corresponding to different weights into a program and introducing the program into software; directly calling the program to control the front extruding plate to automatically finish exhausting work in an actual application process according to the specifications and types of the blood serum bags and the weights of the blood serum bags.

The invention discloses a blood component separator, a management system and method based on blood component separators. The blood component separator comprises a blood member identity input module, a consumable information input module, a control module, a storage, a data output module and a storage medium transfer module. The control module is used for retrieving information data of the storage before update, directly adding new blood member identity information, consumable information and separation process data of the blood component separator to information data before update to form information data after update and then transferring information data to the storage, the data output module and the storage medium transfer module.The management system and management method thereof for separating blood components not only comprise management of single units and management of multiple blood component separators by a server. By adoption of the technical scheme disclosed by the blood component separator, the management system and method based on the blood component separators have following beneficial effects: unified management of information data is performed in a standardized mode; and occurrences of cross-regional collection, excessive collection and frequent collection in a pulp-collecting industry are avoided in order to guarantee physical and mental health of blood members.

The invention provides a pressure monitoring system for a blood component separator. The system includes a blood component separator (1), a controller (2) and a pressure monitoring device (3); and thepressure monitoring device (3) is provided with a pressure sensing transducer (13), the controller (2) is in electrical connection with the blood component separator (1) and the pressure sensing transducer (13) respectively, the pressure monitoring device (3) is in sealed connection with a blood collection pipeline, a fluid channel is formed in the pressure monitoring device (3), the fluid channel is in communication with the blood collection pipeline, and the pressure sensing transducer (13) collects pressure signals of the fluid channel and outputs the signals to the controller (2). According to the system, the pressure sensing transducer is used to collect the pressure signals of the fluid channel and output the signals to the controller, so that pressure change in the pipeline can beaccurately monitored in time, and the reliability of the pressure monitoring of the blood component separator is improved.

The invention discloses a platelet quantitative separation method applied to an automatic blood component separator and can provide a more optimized operation method for platelet separation. The automatic blood component separator comprises a front extrusion plate, a hanging arm, a heat sealing head and an inductive head. The separation method comprises the following steps: centrifuging series of blood collection bags containing constant plasma weight D and different red blood cell weight Gn, extruding the blood collection bags to enable a red blood cell level to reach an inductive head position, recording a front extrusion plate moving distance as an absolute distance Hn, setting extruded plasma volume D1 (D1=D-E) according to the platelet quantity demanded E, sequentially enabling the front extrusion plate to continuously extrude all the blood collection bags till the D1 volume of plasma is extruded, recording a change value relative distance delta n of each of the blood collection bags corresponding to the moving distance at the moment and enabling a corresponding relation among the blood bag specification, the absolute distance and the relative distance to form a program to guide into software for invoking during separation operation. The platelet quantitative separation method disclosed by the invention has the benefits that prepared platelet products are consistent in weight, and the platelet density difference is smaller.

The invention relates to a method for reducing blood waste after blood sampling by a centrifugal bag type blood component separator. After blood platelets are collected, residual blood in part of pipelines in the centrifugal bag type blood component separator is flushed according to the following saline water flushing process that a centrifugal pump rotates anticlockwise, and a blood sampling pumprotates clockwise at the same time; after saline water in a saline water bag passes through a saline water bag connecting pipe, one part of the saline water sequentially flushes residual blood in a second blood return pipe, a blood inlet pipe, a fourth pipeline, a red blood cell conveying pipeline, a first bag body, a centrifugal separation pipeline, an interceptor, a first pipeline and a whole blood bag connecting pipe into a whole blood bag; and the other part of the saline water sequentially flushes residual blood in a first blood return pipe and the whole blood bag connecting pipe into the whole blood bag. By means of the saline water flushing process, more blood after the blood platelets are collected can be conveyed to the human body, so that precious blood resources can be saved, about 290,000 blood donation units of the total blood amount can be saved each year, and meanwhile, the health of blood donors can be guaranteed.

The invention discloses a shaking device and a blood component separator. The shaking device includes a body, a tray arranged above the body, and a support piece for supporting the tray and driving the tray to perform a reciprocating circular arc movement in a vertical direction. It includes a driving mechanism for driving the supporting rocker to swing in the vertical direction. There is a through groove on the top of the fuselage, and the supporting rocker runs through the through groove. The tray is installed on the top of the supporting rocker, and the bottom of the supporting rocker is placed on the The driving mechanism inside the fuselage drives the connection. The blood component separator includes a blood bag extruding device, a weighing device, a heat sealing device and a shaking device. The tray of the shaker device makes a reciprocating circular arc motion in the vertical direction, both back and forth and up and down, so that the preservation solution on the tray and the red blood cells are mixed more evenly, and the red blood cells are prevented from coagulation and agglomeration. The blood component separator has both the blood component separation function and the shaking function, achieving the purpose of shaking while separating.

The invention discloses an extruding and weighing device of a full-automatic blood component separator. The extruding and weighing device comprises a supporting plate, a cylinder positioned below the supporting plate, a transverse z-shaped ejector rod pushed by the cylinder to move up and down, a connecting block arranged above the supporting plate, a weighing sensor, a maintenance solution holding plate and a top extruding plate, the weighing sensor, the maintenance solution holding plate and the top extruding plate are connected with the connecting block, and the maintenance solution holding plate and the weighing sensor are connected and fixed in a proper manner; when the transverse z-shaped ejector rod is driven by the cylinder to move downward, the top extruding plate extrudes a maintenance solution bag placed on the maintenance solution holding plate, and one end, fixed to the connecting block, of the weighing sensor is not supported by the z-shaped ejector rod, so that a weighing function is not realized; when being pushed by the cylinder to move upward, the transverse z-shaped ejector rod penetrates the supporting plate from bottom to top to jack up the connecting block, the weighing sensor and the maintenance solution holding plate, and the weighing sensor is supported by the connecting block to realize the weighing function so as to weigh the maintenance solution bag placed on the maintenance solution holding plate.

The invention belongs to the field of centrifugal bag type blood component separators, and particularly relates to a centrifugal bag type blood component separator. A gas interception part is mountedon a blood return pipeline; the gas interception part comprises a drip-funnel-shaped shell and a filter membrane assembled in the shell; a blood inlet is formed in the upper part of the shell; a bloodoutlet is formed in the lower part of the shell; and the gas interception part is vertically placed. A return filter in a traditional centrifugal bag type blood component separator and a bubble detector on a full-automatic blood component separator are replaced with the gas interception part, so that the structure is simplified, gas containing tiny bubbles can be intercepted, the risk of blood vessel air embolism is avoided, the effect of filtering blood clots and microparticles can be achieved, meanwhile the platelet collection efficiency can be improved, and the comfort level of a blood donor is improved. The invention further provides a gas interception method of the centrifugal bag type blood component separator in a blood return process. The gas interception method is mainly realizedby improving the structure of the centrifugal bag type blood component separator.