Preparation method of ultrasonic-assisted customized 3D printing medical porous renewable sacrum prosthesis

Abstract

The invention relates to a customized medical porous implantable prosthesis capable of regenerating sacrum. The method comprises the following steps: scanning CT cross-sectional image data of the sacrum of a patient by using CT, restoring and establishing a three-dimensional model conforming to the sacrum of the patient through three-dimensional software according to the CT cross-sectional image data, importing the three-dimensional model into a 3D printer, and printing medical nano titanium alloy mixed material powder mixed in different proportions into the sacrum layer by layer by using the 3D printer under the auxiliary control action of ultrasonic enhancement equipment; treating the sacrum through an electronic beam dissolution method, preparing a strontium-loaded micro-nano coating through a magnetron sputtering technology, and finally obtaining the medical porous renewable sacrum prosthesis. The medical porous renewable nano titanium alloy sacrum prosthesis is individualized through 3D printing, has good biological activity and high corrosion resistance, has the mechanical property close to that of human bones, can overcome the defects that reconstruction is difficult and the long-term effect is poor when the prosthesis is implanted after total sacrum resection, and shortens the time needed by a patient to recover load and exercise.

Description

technical field [0001] The invention relates to an implantable prosthesis, in particular to a medical porous regenerable sacral prosthesis with human affinity and mechanical properties close to human bone customized by ultrasound, which is applied in the field of medical implantation. Background technique [0002] Sacral tumor resection has always been a difficult problem in the field of bone tumor surgery. Due to the complex anatomical site of the sacrum, preoperative radiotherapy and chemotherapy, and recurrence cases are common, all of these increase the difficulty of surgical resection of sacral tumors. The sacrum not only has important sacral nerves inside, but also the sacroiliac joint is the only structure that connects the axial bone and the bones of the lower limbs. Therefore, surgical resection of this part has a greater impact on nerve function and structural stability. For sacral tumors, due to the large resection range, the damage to the local stability is ser...

AI Technical Summary

Problems solved by technology

However, this kind of mechanical fixation has the following problems because the sacrum is not reconstructed: 1) After the sacrum is resected, a large cavity will be formed locally. If the sacral prosthesis is not implanted, there will be a long-term residual cavity and effusion, which will cause infection; 2) ) Sacral resection will cause pelvic internal organs such as rectum and colon to herniate to the posterior side (dorsal side), resulting in the patient’s stool disorder. 3) The screw and the bone are mechanically connected, and bone growth cannot be performed between the two And to achieve the final biological healing, long-term activities will inevitably lead to the pull out of the screw from the bone and the breakage of the titanium rod / screw

However, the main body of the prosthesis is not customized, and its integration with the lumbar bone surface and later bone ingrowth are worse than those of the 3D printed prosthesis. At the same time, it lacks the structural design to increase the long-term biological fixation of the prosthesis, which may easily lead to internal fixation failure.

To sum up, at present, there is no successful design at home and abroad that not only meets the structural and mechanical requirements of the human body after total sacrectomy, but also promotes the bony fusion of the lumbar spine and bilateral ilium after implantation, thereby rebuilding the mechanical support of the limbs and shortening the recovery time of the patient. Sacral prosthesis for time required for weight bearing and movement

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