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Drunkenness-delaying liver protecting tablets and preparation method thereof

The technology of protecting liver tablet and protective agent is applied in the field of protecting liver tablet for delaying drunkenness and its preparation, which can solve the problems of large degree of liver damage, difficulty in relieving, drunk driving, etc. Effect

Inactive Publication Date: 2020-01-17
安佰超
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, drinking can easily lead to bad social phenomena such as fighting and drunk driving.
[0004] In the prior art, a large number of techniques for relieving alcohol and protecting the liver have been studied for alcohol drinkers. However, the technologies for relieving alcohol and protecting the liver in the prior art have many defects, mainly focusing on: taking into account the alcohol and liver The function of clearing away heat and reducing fire, promoting liver detoxification is weak, and it is difficult to relieve symptoms such as headache, dizziness, nausea, vomiting, thirst, getting angry, etc. of excessive drinkers, so that the degree of liver damage is still relatively large

Method used

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  • Drunkenness-delaying liver protecting tablets and preparation method thereof
  • Drunkenness-delaying liver protecting tablets and preparation method thereof
  • Drunkenness-delaying liver protecting tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051]A liver-protecting tablet for delaying drunkenness, which comprises the following raw materials in parts by weight: 200 g of crow's petal extract, and 400 g of a gastric mucosa protective agent.

Embodiment 2

[0053] A liver-protecting tablet for delaying drunkenness, comprising the following raw materials in parts by weight: 200g of crow's petal extract, 400g of gastric mucosal protective agent, 200g of lactose, 100g of xylitol, 5g of mint essence, 5g of banana essence, and 5g of magnesium stearate ;

[0054] The gastric mucosal protective agent is: aluminum magnesium carbonate;

[0055] The preparation method of the liver-protecting tablet for delaying drunkenness comprises the following steps:

[0056] (1) preparing the laurel petal extract;

[0057] 1.1, pulverize the crow petals, extract the crow petal powder with a concentration of 80% ethanol backflow, and after the extraction is completed, filter and remove the filter residue to obtain the filtrate; repeat this three times, and combine the obtained filtrates for three times of reflux extraction to obtain the total filtrate; concentrate and recover the total filtrate under reduced pressure. Ethanol in the filtrate, to obtai...

Embodiment 3

[0068] A liver-protecting tablet for delaying drunkenness, comprising the following raw materials in parts by weight: 300g of crow's petal extract, 450g of gastric mucosal protective agent, 250g of lactose, 150g of xylitol, 8g of mint essence, 8g of banana essence, and 8g of magnesium stearate ;

[0069] The gastric mucosal protective agent is: potassium citrate;

[0070] The preparation method of the liver-protecting tablet for delaying drunkenness comprises the following steps:

[0071] (1) preparing the laurel petal extract;

[0072] 1.1, pulverize the crow's petals, and extract the crow's petals powder with a concentration of 85% ethanol backflow. After the extraction is completed, filter and remove the filter residue to obtain the filtrate; repeat this three times, and combine the obtained filtrates for three reflux extractions to obtain the total filtrate; concentrate under reduced pressure and recover the total filtrate. Ethanol in the filtrate, to obtain colloidal aq...

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Abstract

The invention discloses drunkenness-delaying liver protecting tablets and a preparation method thereof. The liver protecting tablets comprise 200-400 parts of Tulipa edulis bulb extract and 400-500 parts of a gastric mucosa protecting agent. The liver protecting tablets have the advantages that the Tulipa edulis bulb extract with colchicine removed and the gastric mucosa protecting agent are usedas main drugs, a protection film is formed in vivo by the drugs, activity of alanine transaminase (ALT) and aspartate amino transferase (AST), total antioxidant capacity (TEAC), activity of acetaldehyde dehydrogenase (ALDH), activity of glutathione peroxidase (GPx), activity of catalase (CAT), total SOD activity, content of reduced glutathione (GSH) and content of malonaldehyde (MDA) in vivo can be adjusted to slow down alcohol absorption while inhibiting excessive oxidative stress caused by alcohol, an endogenous antioxidation system is protected, and activity of ALDH is improved, so that efficacy of delaying drunkenness and improving alcoholic liver injury is realized.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to liver-protecting tablets for delaying drunkenness and a preparation method thereof. Background technique [0002] Wine plays an important role in people's communication and entertainment and life. With the improvement of people's living standards, the consumption of alcohol is increasing year by year. While it brings benefits to society and mankind, it also causes certain harm to the human body and various bad behaviors. [0003] Alcohol has been listed as a primary carcinogen by the United Nations. When alcohol is absorbed in the body, many toxic metabolites are produced in the liver metabolism process, which can easily lead to liver damage, and then damage other organs of the human body. In the United States, alcoholic cirrhosis is one of the top seven diseases with high mortality, accounting for more than 80% of the incidence of cirrhosis. my country's alcohol consumption...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/20A61P1/16A61P39/02A61K31/7024A61K33/10A61K33/245
CPCA61K9/2018A61K31/7024A61K33/10A61K33/245A61K36/896A61K2236/333A61K2236/39A61P1/16A61P39/02A61K2300/00
Inventor 安佰超
Owner 安佰超
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