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159 results about "Ventricular tachycardia" patented technology

Fast heart beat rhythm of the ventricles.

Cardiac arrhythmia detector using ECG waveform-factor and its irregularity

A cardiac monitor is provided that monitors the condition of the heart of a cardiac patient and generates signals indicating one of several conditions, such as supraventricular tachycardia, ventricular tachycardia and ventricular fibrillation. In order to generate these signals, the ECG from the patient is analyzed to determine a cardiac interval and heart rate, as well as a waveform factor and a waveform factor irregularity. The waveform factor is derived from the average of the ECG amplitudes during a cardiac interval and the peak value of the ECG during the same interval. Preferably, a running average is calculated over several intervals. This waveform factor is then used to detect shockable ventricular arrhythmia. The waveform factor irregularity is indicative of the variability of the waveform factor and is used to differentiate between ventricular tachycardia and ventricular defibrillation.
Owner:ZOLL MEDICAL CORPORATION

Defibrillation system

A method of treating a patient for ventricular tachycardia using a wearable defibrillator includes monitoring the patient for a predetermined condition via one or more electrodes on the defibrillator, sending a message to the patient in response to the predetermined condition, activating the defibrillator so that the defibrillator delivers defibrillation energy to the patient, and storing at least one of the results of the monitoring, sending and activating steps in a memory on the defibrillator. The method also includes downloading information stored in the memory of the defibrillator to a base station having an external interface, and transmitting the information downloaded from the memory of the base station to an external location via the external interface of the base station.
Owner:ZOLL MEDICAL CORPORATION

System and method for determining reentrant ventricular tachycardia isthmus location and shape for catheter ablation

A method for identifying and localizing a reentrant circuit isthmus in a heart of a subject during sinus rhythm, including: a) receiving electrogram signals from the heart during sinus rhythm via electrodes; b) storing the electrogram signals; c) creating a map based on the electrogram signals; d) finding a center reference activation location on the map; e) defining measurement vectors originating from the center reference activation location; f) selecting from the measurement vectors a primary axis vector indicating a location of the reentrant circuit isthmus in the heart; g) finding threshold points of electrogram signals on the map; h) connecting the threshold points to form a polygon indicating a shape of the reentrant circuit isthmus in the heart.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Treatment of cardiac arrhythmia utilizing ultrasound

A noninvasive or minimally invasive treatment of cardiac arrhythmia such as supraventricular and ventricular arrhythmias, specifically atrial fibrillation and ventricular tachycardia, by treating the tissue with heat produced by ultrasound, (including High Intensity Focused Ultrasound or HIFU) intended to have a biological and / or therapeutic effect, so as to interrupt or remodel the electrical substrate in the tissue area that supports arrhythmia.
Owner:SONORHYTHM

Classification of supraventricular and ventricular cardiac rhythms using cross channel timing algorithm

A system and method for classifying cardiac complexes sensed during a tachycardia episode. A first cardiac signal and a second cardiac signal are sensed, where the first cardiac signal has a voltage. A first cardiac complex and a second cardiac complex of a cardiac cycle are detected in the first and second cardiac signal, respectively. A predetermined alignment feature is identified in the second cardiac complex. A datum is defined, or positioned, at a specified interval from the predetermined alignment feature of the second cardiac complex. Voltage values are then measured from the first cardiac complex at each of two or more measurement intervals from the datum. The voltage values are then compared voltage values measured from NSR cardiac complexes to classify the first cardiac complex is either a ventricular tachycardia complex or a supraventricular tachycardiac complex.
Owner:CARDIAC PACEMAKERS INC

In vivo simulator for microwave treatment

Method and apparatus are provided for propagating microwave energy into heart tissues to produce a desired temperature profile therein at tissue depths sufficient for thermally ablating arrhythmogenic cardiac tissue to treat ventricular tachycardia and other arrhythmias while preventing excessive heating of surrounding tissues, organs, and blood. A wide bandwidth double-disk antenna (700) is effective for this purpose over a bandwidth of about six gigahertz. A computer simulation provides initial screening capabilities for an antenna such as antenna, frequency, power level, and power application duration. The simulation also allows optimization of techniques for specific patients or conditions. In operation, microwave energy between about 1 Gigahertz and 12 Gigahertz is applied to monopole microwave radiator (600) having a surface wave limiter (606). A test setup provides physical testing of microwave radiators (854) to determine the temperature profile created in actual heart tissue or ersatz heart tissue (841). Saline solution (872) pumped over the heart tissue (841) with a peristaltic pump (862) simulates blood flow. Optical temperature sensors (838) disposed at various tissue depths within the heart tissue (841) detect the temperature profile without creating any electromagnetic interference. The method may be used to produce a desired temperature profile in other body tissues reachable by catheter (510) such as tumors and the like.
Owner:NASA

Method and apparatus for predicting recurring ventricular arrhythmias

An implantable medical device and method are provided for assessing autonomic tone and risk factors associated with arrhythmias and, based on this assessment, an early recurrence of ventricular tachycardia or ventricular fibrillation is predicted. Specifically, changes in R—R interval, heart rate variability, patient activity, and myocardial ischemia are measured prior to and after a detected an arrhythmia episode. A recurrence score is calculated as a weighted sum of measured parameters and compared to a prediction criterion. The prediction criterion may be a preset threshold score or an individualized episode template based on previously calculated recurrence scores associated with recurring episodes. Stored parameters and episode-related data may be downloaded for offline analyses for optimizing prediction criteria and monitoring patient status.
Owner:MEDTRONIC INC

System and method for arrhythmia discrimination

The present invention provides a system and a method for discriminating supraventricular tachyarrhythmias from ventricular arrhythmias during a tachycardia episode. First cardiac signals and second cardiac signals are sampled for cardiac complexes. A first feature on the first cardiac signal and a second feature on the second cardiac signal are utilized to determine an average time difference for a plurality of normal sinus rhythm complexes. A time difference between the first feature and the second feature is then determined for each cardiac complex of a tachycardiac rhythm. The cardiac complex is characterized as a ventricular tachycardia complex if the time difference exceeds the average time difference by a predetermined amount. Otherwise, it is classified as VT if its morphology after alignment is different from that during normal sinus rhythm.
Owner:CARDIAC PACEMAKERS INC

System and method for complexity analysis-based cardiac tachyarrhythmia detection

InactiveUS6490478B1Clearer and reliable indicationAvoids possible misidentificationsHeart defibrillatorsHeart stimulatorsEcg signalVentricular tachycardia
A system and method based on electrocardiogram (ECG) complexity analysis for real-time detecting shockable ventricular fibrillation (VF) and ventricular tachycardia (VT), and discriminating them from non-shockable tachyarrhythmia (e.g. supraventricular tachycardia (SVT) and atrial fibrillation (AF)) and high-frequency noise. In the disclosed invention, complexity measure CM (0 to 100), quantitatively characterizing the complexity nature of the non-linear dynamics underlying cardiac arrhythmia, is extracted from the sensed patient ECG signal using ECG complexity analysis. From the calculated complexity measure, by three thresholds (low complexity threshold (LCT), mediate complexity threshold (MCT), and high complexity threshold (HCT)), different kinds of tachyarrhythmia (i.e. heart rate (HR) above a preset rate threshold) and high-frequency noise are discriminated from each other: for non-shockable tachyarrhythmia, CM<=LCT; for VT, LCT<CM<=MCT; for VF, MCT<CM<=HCT; and for high-frequency noise, HCT<CM. The disclosed system and method can be used as a primary cardiac tachyarrhythmia detection scheme or as a backup system to reconfirm arrhythmia detection using conventional techniques.
Owner:ZOLL MEDICAL CORPORATION

Automated pace-mapping for identification of cardiac arrhythmic conductive pathways and foci

Ventricular tachycardia signals are induced in a living subject. Pace-mapped signals are then obtained from multiple points within the ventricle, and automatically compared numerically with the induced signals. Recognition of a high degree of cross correlation between the induced signals and one or more of the pace-mapped signals identifies arrhythmogenic foci or pathways, which may then be ablated, so that the arrhythmia becomes non-inducible.
Owner:BIOSENSE WEBSTER INC

Discrimination of supraventricular tachycardia and ventricular tachycardia events

A method and system for discrimination of supraventricular tachycardia and ventricular tachycardia events. Morphological features points are extracted from normal sinus rhythm (NSR) complexes and used to generate a NSR template. A numerical convolution is performed using the NSR template and the feature points for each sensed NSR to give a NSR filter output. Using a plurality of NSR complexes, a median NSR filter output template is determined, where the median NSR filter output template has a median value for each value in the NSR filter output. The median NSR filter output template is then used during a tachycardia event to distinguish tachycardia events as either ventricular tachycardia events or supraventricular tachycardia events.
Owner:CARDIAC PACEMAKERS INC

Synthetic apelin mimetics for the treatment of heart failure

The invention provides a synthetic polypeptide of Formula I′:or an amide, an ester or a salt thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Owner:NOVARTIS AG

Wearable cardioverter defibrillator (WCD) system informing patient that it is validating just-detected cardiac arrhythmia

In some embodiments, a wearable cardioverter defibrillator (“WCD”) system may output an opening human-perceptible indication, after detecting a shockable cardiac arrhythmia but before validating it. This may succeed in informing the patient that the WCD system is working, and in particular analyzing a just-detected cardiac arrhythmia. The information may give comfort and confidence to the patient who may be conscious, and be experiencing only ventricular tachycardia but not ventricular fibrillation.
Owner:WEST AFFUM HLDG DAC

Automated pace-mapping for identification of cardiac arrhythmic conductive pathways and foci

Ventricular tachycardia signals are induced in a living subject. Pace-mapped signals are then obtained from multiple points within the ventricle, and automatically compared numerically with the induced signals. Recognition of a high degree of cross correlation between the induced signals and one or more of the pace-mapped signals identifies arrhythmogenic foci or pathways, which may then be ablated, so that the arrhythmia becomes non-inducible.
Owner:BIOSENSE WEBSTER INC

Method and system for performing ablation to treat ventricular tachycardia

A system and method of treating tachycardias and similar syndromes by the use of catheter ablation of tissue is described. A computed tomography (CT)-like image of the heart is obtained and processed to segment the various types of tissue. Papillary muscle areas are identified and displayed differently from the other nearby tissues so that the muscles can be avoided during treatment to avoid or minimize damage to the muscles during ablation treatment. Electrophysical data and scar tissue may also be identified in the image, which may be of the endoscopic type. The position of the catheter may be displayed as a synthetic image on the endoscopic view.
Owner:SIEMENS HEALTHCARE GMBH

Automated Assessment Of Atrioventricular And Ventriculoatrial Conduction

ActiveUS20090143832A1Restore normal sinus rhythmHeart defibrillatorsHeart stimulatorsVentricular dysrhythmiaInappropriate shock
A method discriminates between ventricular arrhythmia and supraventricular arrhythmia by determining the direction of an electrical signal conducted through the atrioventricular node. An implantable cardiac defibrillator provides atrioventricular and ventriculoatrial pacing bursts to determine if an arrhythmia with a 1:1 atrial to ventricular relationship is due to ventricular tachycardia or supraventricular tachycardia. This discrimination capability reduces the incidence of inappropriate shocks from dual-chamber implantable cardiac defibrillators to near zero and provides a method to differentially diagnose supraventricular tachycardia from ventricular tachycardia.
Owner:UNIVERSITY OF PITTSBURGH

Method and apparatus for detection and treatment of tachycardia and fibrillation

The invention relates to devices that detect and / or treat tachyarrhythmias. The invention includes software systems that distinguish among various tachyarrhythmias in order to provide treatment for specific tachyarrhythmias. One aspect of the invention employs a methodology to provisionally detect ventricular tachycardia and / or fibrillation and thereafter apply a discrimination function to a series of measured intervals preceding the provisional detection. Discrimination is accomplished by sorting the intervals preceding provisional detection into bins corresponding to interval ranges and examining the relative distribution of the intervals within the bins.
Owner:MEDTRONIC INC

Methods and devices for three-stage ventricular therapy

Methods and apparatus for a three-stage ventricular cardioversion and defibrillation therapy that treats ventricular tachycardia and fibrillation at low energy levels. An implantable therapy generator adapted to generate and selectively deliver a three-stage ventricular therapy and at least two leads operably each having at least one electrode adapted to be positioned proximate the ventricle of the patient. The device is programmed to deliver a three-stage therapy via both a far-field configuration and a near-field configuration of the electrodes upon detection of a ventricular arrhythmia. The three-stage therapy includes a first stage for unpinning of one or more singularities associated with the ventricular arrhythmia, a second stage for anti-repinning of the one or more singularities, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of the one or more singularities associated delivered via the near-field configuration of the electrodes.
Owner:WASHINGTON UNIV IN SAINT LOUIS

Synthetic apelin mimetics for the treatment of heart failure

The invention provides a synthetic polypeptide of Formula I′:or an amide, an ester or a salt thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Owner:NOVARTIS AG

Enhanced rhythm identification in compression corrupted ECG

A method is provided for analyzing the condition of a patient to determine whether or not a defibrillation shock should be applied, without stopping CPR (primarily chest compressions). While chest compressions continue to be applied to the victim, the system differentiates between (1) a perfusing rhythm that has the capability of leading to a beating heart without a shock and (2) ventricular fibrillation (VF) which sometimes occurs in the presence of ventricular tachycardia (VT), in which there is no capability for leading to a beating heart without a shock. Defibrillation shocks should be applied only when needed and that is in the presence of VF and sometimes in the presence of VT. Electrocardiographic (ECG or EKG) signals obtained from electrodes applied to the patient's chest are analyzed so that the presence of a QRS signal characteristic of a rhythm which has the potential of supporting a beating heart, or the absence of a QRS signal which indicates ventricular fibrillation, may be detected in the presence of artifacts resulting from chest compressions.
Owner:ZOLL MEDICAL CORPORATION

Method and apparatus for predicting arrhythmias using diurnal heart rate

A method of predicting an arrhythmia, such as ventricular tachycardia, for example, in a medical device using a quantitative measure in order to allow assessment of patient risk and to enable preventative interventions by the device and clinicians. The trending of day and night average heart rates, along with patient physical activity can be analyzed to provide prediction of impending arrhythmia within weeks. By examining day and night average heart rate for crossover points, where the night heart rate equals or exceeds the day rate, and monitoring for a concomitant elevation in the night heart rate from a reference value, specific days heralding an increased risk of arrhythmia can be determined and therapy can be updated accordingly
Owner:MEDTRONIC INC

Method and apparatus for discriminating ventricular and supraventricular tachyarrhythmias

A system and method are provided for discriminating supra-ventricular tachycardia (SVT) from ventricular tachycardia (VT). A monitoring EGM signal is acquired during a sensing window timed according to the time of R-wave detection on a reference EGM signal. A normal sinus rhythm (NSR) template is generated using the monitoring EGM signal during the time-referenced sensing window. During an unknown rhythm, the monitoring EGM signal sensed during the time-referenced sensing window is compared to the NSR template for use in computing a morphology metric. The morphology metric is compared to a VT / VF detection threshold for discriminating SVT from VT / VF.
Owner:MEDTRONIC INC

Rhythm identification in ECG for resuscitation

A method is provided for controlling an automatic external defibrillator without stopping CPR (primarily chest compressions). While chest compressions continue to be applied to the victim, the system differentiates between (1) a perfusing rhythm that has the capability of leading to a beating heart without a shock and (2) ventricular fibrillation (VF) which sometimes occurs in the presence of ventricular tachycardia (VT), in which there is no capability for leading to a beating heart without a shock. Defibrillation shocks should be applied only when needed and that is in the presence of VF and sometimes in the presence of VT. Electrocardiographic (ECG or EKG) signals obtained from electrodes applied to the patient's chest are analyzed so that the presence of a QRS signal characteristic of a rhythm which has the potential of supporting a beating heart, or the absence of a QRS signal which indicates ventricular fibrillation, may be detected in the presence of artifacts resulting from chest compressions.
Owner:ZOLL MEDICAL CORPORATION

Method and system for performing ablation to treat ventricular tachycardia

A system and method of treating tachycardias and similar syndromes by the use of catheter ablation of tissue is described. A computed tomography (CT)-like image of the heart is obtained and processed to segment the various types of tissue. Papillary muscle areas are identified and displayed differently from the other nearby tissues so that the muscles can be avoided during treatment to avoid or minimize damage to the muscles during ablation treatment. Electrophysical data and scar tissue may also be identified in the image, which may be of the endoscopic type. The position of the catheter may be displayed as a synthetic image on the endoscopic view.
Owner:SIEMENS HEALTHCARE GMBH
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