49 results about "Tissue cassette" patented technology

Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.

A method and apparatus for embedding cells that utilizes a flow-through embedding technique maximizes the efficiency of extractions and decreases time for embedding the cell fragments, minimizes cell loss, and automatically positions cell samples at the position in which a microtome blade will section them. The apparatus includes a cell flow pathway defined by an inflow tube for delivering cell fragments from a cell sample to a sample port. The sample port is in fluid communication with a tissue cassette having attached thereto a filter. The cell flow pathway is in communication with a reagent flow pathway for delivering the reagents through the sample port to the cassette. The apparatus is configured such that the application of pressure directs the cell fragments from the cell sample through the cell flow pathway, and effects delivery of the reagents through the reagent flow pathway. The apparatus produces an embedded cell block having concentrated cells near the plane of the block to be sectioned in a quick and efficient manner.

An embodiment of the method of the invention is a method of automating information flow in a laboratory performing tissue staining comprising positioning a networked label printer adjacent to a cutting station, the printer configured to access patient data directly or indirectly from the hospital LIS, the printer being configured with a data element scanner in electronic communication with said printer; inputting data from a tissue cassette-associated data element at said printer, whereby inputting data comprises reading the data from the cassette-associated data element and uploading the cassette data to the LIS; identifying the corresponding test protocol identifier and then downloading the test protocol data to the printer; printing information on labels corresponding to each test specified in the LIS for the patient; attaching a single label to each slide; and cutting a tissue section for each labeled slide and mounting the section on the slide.

An improved biopsy kit for the collection, storage, transportation, and processing of biopsy tissue samples is disclosed. The disclosed biopsy kit consists of a typical specimen container and an improved tissue cassette with adhesively attached polyvinyl alcohol foam pads on both the base and lid portions. An excised tissue sample is sandwiched between the pads upon cassette closure, simultaneously isolating and securing the sample in its original orientation. Superior wicking, absorbency, and moisture retention rate of these polyvinyl alcohol pads allows maximum tissue fixation as well as maintains sample integrity. Once the tissue is placed by the physician at the patient's side, it remains there until the tissue is ready to be processed. This eliminates transfer errors as well as tissue loss.

The present invention relates to a kit for taking biopsies, resections, excisions, and / or autopsies. Moreover, the present invention relates to methods of taking biopsies resections, excisions, and / or autopsies using the kit of the present invention. The kits and methods of the present invention allow for fewer errors, decreased turn around time and / or more rapid processing due to a cassette and specimen numbering system that is simplified and superior over that which has been previously disclosed in the prior art. The kit of the present invention comprises one or more tissue cassettes, and optionally one or more bottles of formalin and optionally, other components.

A unitary assembly of biological specimen support articles, arranged in a stack in which successive articles are secured in positional sequence by a tape. The tape in one embodiment is of loop form, e.g., folded back on itself with a first portion detachably adhesively secured to the stack and with the second portion back-folded over the first portion and extending beyond the stack in a free end that may be manually grasped to peel away the tape from the stack, when the stack is placed in a dispensing hopper with the free end accessed for manual grasping thereof. By stripping the tape from the stack after the stack is positioned in the dispensing hopper, the component support articles, e.g., tissue cassettes or microscope slides, are freed for subsequent dispensing and use.

A unitary assembly of biological specimen support articles, arranged in a stack in which successive articles are secured in positional sequence by a tape. The tape in one embodiment is of loop form, e.g., folded back on itself with a first portion detachably adhesively secured to the stack and with the second portion back-folded over the first portion and extending beyond the stack in a free end that may be manually grasped to peel away the tape from the stack, when the stack is placed in a dispensing hopper with the free end accessed for manual grasping thereof. By stripping the tape from the stack after the stack is positioned in the dispensing hopper, the component support articles, e.g., tissue cassettes or microscope slides, are freed for subsequent dispensing and use.

An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.

The present invention relates to a kit for taking biopsies, resections, excisions, and / or autopsies. Moreover, the present invention relates to methods of taking biopsies resections, excisions, and / or autopsies using the kit of the present invention. The kits and methods of the present invention allow for fewer errors, decreased turn around time and / or more rapid processing due to a cassette and specimen numbering system that is simplified and superior over that which has been previously disclosed in the prior art. The kit of the present invention comprises one or more tissue cassettes, and optionally one or more bottles of formalin and optionally, other components.

Labels are permanently attached to a substrate, e.g., a tissue cassette, by use of a staking device. The device comprises a staker assembly and a cassette fixture assembly. The cassette fixture assembly includes a slot and a clamping assembly for securing the cassette within the device. The staker assembly includes a set of probes that are heated and sequentially moved into a position to burn a hole in a label that is provisionally attached to the cassette, and then the substrate is melted and displaced through the hole to form a collar bond that permanently attaches the label to the cassette. The label remains attached to the cassette when exposed to harsh environmental conditions, e.g., high heat, high humidity, solvents, etc.

An apparatus for holding a tissue sample having a retaining member with a first tissue engaging surface and at least one biasing element. The first tissue engaging surface is moveably attached to the retaining member. The apparatus also has a base comprising a second tissue engaging surface which is configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other. The apparatus also has a retracting member connected to the retaining member which is configured to retract the first tissue engaging surface and compress the biasing element to form a gap between the tissue sample and one of the first tissue engaging surface and the second tissue engaging surface.

An apparatus for holding a tissue sample having a retaining member with a first tissue engaging surface and at least one biasing element. The first tissue engaging surface is moveably attached to the retaining member. The apparatus also has a base comprising a second tissue engaging surface which is configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other. The apparatus also has a retracting member connected to the retaining member which is configured to retract the first tissue engaging surface and compress the biasing element to form a gap between the tissue sample and one of the first tissue engaging surface and the second tissue engaging surface.

An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.

A system for preparing a cytoblock includes an instrument and a series of associated supplies. The instrument provides all of the mechanical instrumentation necessary for preparation of the cytoblock in a single piece of laboratory equipment. In one embodiment, the instrument includes a centrifuge, a supernatant and moisture removal device, an incubation chamber, and a mixing device. The associated supplies may be provided in the form of a kit and include a centrifuge tube containing a fixative, a matrix container containing a matrix material, a transfer tube, a tamping device, a tissue cassette, an embedding tray, and an embedding block. A method of preparing a cytoblock using the kit. The cytoblock can include a single cell population, or can include several distinct cell populations.

A surgeon training apparatus includes an operating table and an immersion tank carried by the operating table and configured to contain liquid. A thoracic animal tissue cassette is configured to hold at least harvested animal lung tissue for surgeon training. An inflator is configured to be coupled to the harvested animal lung tissue. An actuator is configured to relatively move the thoracic animal tissue cassette between an operating position above the immersion tank and an immersed position in the liquid within the immersion tank so that the surgeon can test the harvested animal lung tissue for leaks during surgeon training. The surgeon training apparatus may be at a first location at a first geographic point and a remote surgeon station may be at a second location at a second geographic point remote from the first geographic point to allow a remote surgeon to remotely train.

A method for treating a tissue sample including placing at least one tissue sample on an cassette which has: a retaining member, a base and at least one biasing element; placing the at least one tissue sample in the tissue cassette; attaching the base and the retaining member to retain the tissue sample; processing the tissue sample in the tissue cassette with one or more solvents; and embedding the tissue sample in a paraffin to form an portion of paraffin in which the tissue sample is embedded in the tissue cassette, wherein the embedding comprises adding molten paraffin to the interior area of the tissue cassette and allowing the paraffin to become solid.

The present invention relates to a method to turn cassettes for biological tissue samples into devices traceable with RFID technology, using a system with inlays tagged with an RFID chip, which inlays are placed in the tissue sample chamber of the tissue cassettes, wherein the part of the inlay that contains the antenna of the RFID chip is running around an opening or is folded together. Such inlays do not risk to be affected by damaging forces outside the tissue cassettes. With an inlay that at every suitable moment can be positioned in the tissue sample chamber for one or more limited periods of time, or indefinitely, tissue cassettes can tracked and traced with RFID technology without the fear of destroying the RFID chip during processing that involves the use of a microwave oven. During that period the inlay can be temporarily removed from the tissue cassette. The inlays are further designed to: allow sufficient flow of fluids through cassette lids and the bottom of the tissue cassettes. leave as much room as possible for tissue samples. fit in cassettes with and without an inner tissue sample chamber. enable the use of different RFID chips and antennas. enable fixation in a cassette, without additional fixation means.

A method and apparatus for embedding cells that utilizes a flow-through embedding technique maximizes the efficiency of extractions and decreases time for embedding the cell fragments, minimizes cell loss, and automatically positions cell samples at the position in which a microtome blade will section them. The apparatus includes a cell flow pathway defined by an inflow tube for delivering cell fragments from a cell sample to a sample port. The sample port is in fluid communication with a tissue cassette having attached thereto a filter. The cell flow pathway is in communication with a reagent flow pathway for delivering the reagents through the sample port to the cassette. The apparatus is configured such that the application of pressure directs the cell fragments from the cell sample through the cell flow pathway, and effects delivery of the reagents through the reagent flow pathway. The apparatus produces an embedded cell block having concentrated cells near the plane of the block to be sectioned in a quick and efficient manner.

A histologic tissue sample support device (200) includes a tissue cassette (112), a frame (14), and a lid (118"). The tissue cassette (112) has a recess (112b) including a body (112a) with at least one side wall and a bottom wall (112c) and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette (112) is movably coupled to the frame (14). The lid (118") is separably coupled to a peripheral portion (16) of the frame (14). When the lid (118") is separated from the peripheral portion (16), the lid (118") and the tissue cassette (112) are capable of moving from a first position to a second position with respect to the frame (14), and in the second position thebottom wall (112c) and at least a portion of the side wall extend beyond a bottom edge of the frame (14) for sectioning in the microtome.

A tissue dispensing system with a rigid overshell having 5 sides and an opened bottom with a tissue withdrawal opening in the top is adapted to receive a bend-to-open pack containing a clip of tissue sheets enwrapped in a capaciously sized overwrap having a medial line of weakness formed therein and situated to allow withdrawal of tissue through the tissue withdrawal opening after the line of weakness is ruptured and the tissue pack is placed in the overshell.

A method for treating a tissue sample including placing at least one tissue sample on an cassette which has: a retaining member, a base and at least one biasing element; placing the at least one tissue sample in the tissue cassette; attaching the base and the retaining member to retain the tissue sample; processing the tissue sample in the tissue cassette with one or more solvents; and embedding the tissue sample in a paraffin to form an portion of paraffin in which the tissue sample is embedded in the tissue cassette, wherein the embedding comprises adding molten paraffin to the interior area of the tissue cassette and allowing the paraffin to become solid.

The present invention relates to a tissue cassette which comprises a shell composed of a plurality of walls and a bottom. The shell is equipped with a mechanism used for positioning a tissue sample on the bottom. The present invention also relates to a method comprising the following steps of providing the tissue cassette, introducing the tissue sample and positioning the tissue sample on the bottom.

The invention discloses a car tissue box which is convenient for taking tissues, which comprises a box body and a box bottom, the box body and the box bottom form an accommodation space, and the accommodation space is divided into a tissue box and a waste box, and the tissue box and the waste box are respectively Corresponding first and second openings are provided, and the present invention divides the storage space into a tissue box and a waste box, so that the used tissue or other waste can be put into the waste box to avoid affecting environmental sanitation, and through There is a suction cup at the bottom of the box, which can conveniently fix the tissue box on the car, and prevent it from falling easily. When it is difficult to take it out, the lifting plate rises due to the decrease of the tissue in the box due to the decrease in gravity, thereby raising the height of the tissue inside the tissue box, and then it is convenient to take out the tissue, which has high practicability.

Disclosed is a static reading system of codes located on the oblique fronts of histology cassettes.

A tissue cassette assembly includes a housing having a recess formed therein, and a compressible reservoir disposed partially or wholly inside of, or otherwise attached in fluid communication with, the housing recess, the compressible reservoir containing a tissue embedding material. The tissue cassette further includes a port disposed in the housing, the port in fluid communication with the compressible reservoir at one end and terminating in a sample cavity at another end. During operation, the compressible reservoir is compressed or squeezed to release the tissue embedding material into the sample cavity containing the biological sample.

A device for containing and measuring a biological tissue specimen includes a tissue cassette with a ruler or metric device etched, printed, embossed, or designed into the cassette body. The device facilitates the measuring of a tissue specimen accurately, while reducing fatigue or contamination of the tissue sample.

The invention discloses a multifunctional bamboo tissue box. The tissue box is made of bamboo boards and includes a base. The base is provided with a tissue box body and a storage box. There is a toothpick box, the lower bottom surface of the base is provided with a suction cup, the upper part of the tissue box body is detachably provided with a cover, and the cover is provided with a paper-drawing hole, the storage box is divided into several grids by vertical partitions, and the inside of the toothpick box is vertically The cross-section is an inverted trapezoid, the bottom of the toothpick box is provided with an outlet, the width of the outlet is equal to the diameter of the toothpick, and the length is equal to the length of the toothpick. It is facing the exit, one side of the collection tank is fixed on the storage box, the front and rear side walls of the middle part in the length direction of the collection tank are provided with notches, the two notches are oppositely arranged, and the lowest part of the notch is flush with the inner bottom surface of the collection tank; The tissue box can collect various items on the coffee table in one, and it can also prevent the toothpick from falling out.