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Traditional Chinese medicine composition for treating refractory gout and application thereof

A composition and refractory technology, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of easy recurrence, obvious drug toxicity and side effects, etc., and achieve precise curative effect and scientific component distribution. Reasonable, lower uric acid effect

Active Publication Date: 2022-02-11
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the clinical treatment of refractory gout is mainly anti-inflammatory, analgesic and uric acid control. Western medicine mainly includes non-steroidal anti-inflammatory drugs, colchicine and glucocorticoids, etc. The short-term curative effect is significant, but it is easy to relapse, and some drugs are toxic. obvious side effects

Method used

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  • Traditional Chinese medicine composition for treating refractory gout and application thereof

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Effect test

Embodiment 1

[0018] Many cases of patients with refractory gout were treated with the traditional Chinese medicine composition of the present invention, and statistics were made on the treatment of 62 patients, and the statistical data are shown in Table 1 for details.

[0019] 1. Western medicine diagnostic criteria

[0020] (1) Diagnostic criteria for gout

[0021] The diagnostic criteria for gout refer to the classification criteria of the American College of Rheumatology (ACR) in 1977, as follows:

[0022] ① There are specific urate crystals in the joint fluid.

[0023] ② There is tophi, which is confirmed to contain urate crystals by chemical method (murexide test) or polarized light microscope observation.

[0024] ③Having 6 out of 12 of the following clinical, laboratory and X-ray signs:

[0025] a. More than one episode of acute arthritis;

[0026] b. Inflammation peaked within 1 day;

[0027] c. Onset of monoarthritis;

[0028] d. Observation of joint redness;

[0029] e. P...

Embodiment 2

[0065] Case 1: Wang Mou, male, 43 years old, first visit on January 11, 2006. The history of gout was many years. When the attack occurred, the left leg was the main area. The knee, ankle, and big toe were red, swollen, hot and painful. The pain was migratory. Check blood uric acid 650μmol / L. Taking non-steroidal anti-inflammatory drugs, colchicine, uric acid-lowering drugs and other Western medicines failed to control the disease, recurrent attacks. Diagnosed as refractory gout, syndrome of damp-heat turbidity, toxin and blood stasis. Give the Chinese medicine composition of the present invention in the course of treatment: Smilax tuckahoe 40g, Scutellaria 15g, Scutellaria 30g Pittogonia bark 15g, Plantain 15g, Smilax 25g, Guijianyu 15g, Shanzi mushroom 15g, Chen Danxing 10g, Chuan Achyranthes bidentata 15g, Stir-fried Atractylodes 6g, Cortex Phellodendron 9g, Fangji 15g, Raw Coix Seed 15g, 1 dose a day, decocted in the morning and evening. After taking the Chinese medicin...

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Abstract

The invention provides a traditional Chinese medicine composition for treating refractory gout and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating refractory gout is prepared from the following raw materials in parts by weight: 30 to 50 parts of rhizoma smilacis glabrae, 10 to 25 parts of yam rhizome, 25 to 35 parts of herba siegesbeckiae, 10 to 20 parts of cortex erythrinae, 20 to 30 parts of chinaroot greenbrier, 10 to 20 parts of plantain herb, 10 to 25 parts of ramuli euonymi, 10 to 20 parts of edible tulip, 10 to 15 parts of aged arisaema cum bile and 10 to 25 parts of radix cyathulae. The traditional Chinese medicine composition disclosed by the invention can be used for safely and effectively treating refractory gout, and the refractory gout is not easy to relapse.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating refractory gout and an application thereof. Background technique [0002] Gout is a clinical syndrome characterized by abnormal purine metabolism in the body, increased serum uric acid concentration, and chronic deposition of monosodium urate crystals in joint capsules, synovial bursa, cartilage, bone and other tissues due to metabolic and genetic factors, causing inflammatory reactions and lesions. . Recurrent attacks can cause arthritis, soft tissue masses, kidney stones, and urate nephropathy. According to statistics, the prevalence of gout in my country ranges from 0.86% to 2.20%, including 0.83% to 1.98% for men and 0.07% to 0.72% for women, and it is increasing year by year, seriously affecting the quality of life of patients. Patients with refractory gout often present with persistent joint swe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/898A61K36/8994A61P19/06
CPCA61K36/90A61K36/896A61K36/8945A61K36/28A61K36/48A61K36/68A61K36/37A61K36/898A61K36/8884A61K36/21A61K36/59A61K36/716A61K36/355A61K36/24A61K36/8994A61K36/185A61K36/53A61K36/483A61K36/31A61K36/756A61K36/284A61P19/06A61K2300/00
Inventor 周学平周仲瑛周玲玲冯哲方樑付玲
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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