Felon herb flavone dysmenorrhea navel patch

A technique for flavonoids of mugwort and dysmenorrhea, which is applied in the field of medical devices, can solve the problems of low content of active ingredients of mugwort leaves, no warming effect, poor use effect, etc., and achieves the effects of good blood circulation and pain relief, rich variety and simple use.

Inactive Publication Date: 2018-01-19
马述腾
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its mugwort leaf has low content of active ingredients and complex ingredients, which is easy to cause allergies, does not contain heating ingredients, has no warming effect, and the use effect is not good

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Purchase 100kg of fresh mugwort whole herb, manually remove the withered leaves, cut off the roots, wash the sediment, dry, chop, grind with a colloid mill, and collect 93.5kg of homogenate. 30°C, natural pH value, add 0.94kg cellulase powder and 0.94kg pectinase powder, stir evenly, enzymatically hydrolyze for 24 hours, filter with 200 mesh nylon mesh, obtain 49.67kg of filtrate, and obtain raw material coarse powder 5.11 after spray drying kg, dissolve 102.5 kg of raw material coarse powder with 60% ethanol solution, stir until fully dissolved to obtain alcohol extract, use a membrane with a pore size of 45 μm to carry out suction filtration, and retain the suction filtrate. Use a modified cellulose membrane with a molecular weight cut-off of 30kD to perform ultrafiltration to remove impurities from the suction filtrate, add an equal volume of 60% ethanol solution, retain the filtrate, and then concentrate the filtrate with a modified cellulose membrane with a molecula...

Embodiment 2

[0028] Purchase 200kg of fresh mugwort whole herb, manually remove the withered leaves, cut off the roots, wash the sediment, dry it, chop it, grind it with a colloid mill, and collect 188.2kg of the homogenate. 30°C, natural pH value, add 3.76kg cellulase powder and 4.33kg pectinase powder, stir evenly, enzymolyze for 24 hours, filter with 200 mesh nylon mesh, obtain 96.92kg of filtrate, and obtain raw material coarse powder 11.73kg after spray drying kg, dissolve 258.1 kg of coarse raw material powder with 60% ethanol solution, stir until fully dissolved to obtain alcohol extract, use a membrane with a pore size of 45 μm for suction filtration, and retain the suction filtrate. Use a modified cellulose membrane with a molecular weight cut-off of 30kD to perform ultrafiltration to remove impurities from the suction filtrate, add an equal volume of 60% ethanol solution, retain the filtrate, and then concentrate the filtrate with a modified cellulose membrane with a molecular wei...

experiment example

[0030] 1. Select a case

[0031]The 243 confirmed cases were all outpatients with dysmenorrhea, female; the youngest was 15 years old and the oldest was 39 years old; the shortest course of disease was 0.5 years and the longest was 23 years. The outpatients were divided into 3 groups on average, 81 people in each group, and the control group was umbilical patch without mugwort flavonoid extract.

[0032] 2. Diagnostic criteria

[0033] Those who have the symptoms mentioned in 1 above, especially before and after menstruation or during menstruation, have lower abdominal cramping pain and general discomfort, which seriously affect the daily life of the patient, and they are all diagnosed with dysmenorrhea.

[0034] 3. Treatment plan

[0035] All patients diagnosed with dysmenorrhea were treated with acupoint sticks of the present invention. The acupoint sticks were pasted on the navel, removed after 12 hours of sticking, and treated from 1 week before the menstrual period to 1...

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PUM

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Abstract

The invention belongs to the field of a medical appliance, and particularly relates to a felon herb flavone dysmenorrhea navel patch. The felon herb flavone dysmenorrhea navel patch is characterized in that a navel patch substrate is prepared from the following ingredients in percentage by weight: 20 to 25 percent of felon herb flavone extracts, 0.05 to 0.5 percent of heat sensitizers, 4.5 to 5.5percent of penetrants, 3 to 5 percent of ethyl alcohol, 5 to 7 percent of binding agents, 0.05 to 1 percent of thickening agents, 8 to 12 percent of humectants, 0.5 to 2 percent of excipients and purified water for reaching the total percentage of 100 percent. The felon herb flavone dysmenorrhea navel patch has the beneficial effects that the extraction process of the felon herb flavone is simple;the consumption of organic solvents is low; the flavone content in the product can reach 23.79 percent to the highest degree; the types are rich; the use of the felon herb flavone dysmenorrhea navelpatch is simple; no harmful gas is generated; in the use process, the hot feeling exists; the flavone ingredients can easily penetrate through the skin to be absorbed by the human body; the better effects of promoting blood circulation and relieving pain are achieved; the felon herb flavone dysmenorrhea navel patch belongs to a good choice for replacing conventional moxibustion to treat dysmenorrhea.

Description

technical field [0001] The invention belongs to the field of medical equipment, and in particular relates to a mugwort flavone dysmenorrhea umbilical patch. Background technique [0002] Dysmenorrhea is currently the most common disease in gynecology. The incidence rate of dysmenorrhea among women in my country is 33.19%, and 14% of workers seriously affect it. It is currently believed that dysmenorrhea is caused by excessive contraction of uterine smooth muscle, slow uterine blood flow, or uterine ischemia. Artemisia mugwort is a perennial herb of the genus Artemisia argyi in the family Asteraceae. Its leaves are used as medicine. It tastes pungent, bitter, warm in nature and slightly poisonous. It enters the liver, spleen and kidney meridians. It has the effects of dispelling cold and relieving pain, warming meridians and stopping bleeding. Artemisia argyi leaves are widely used clinically. Treatment of cold coagulation and blood stasis type dysmenorrhea. Modern studies ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/282A61K9/70A61K47/32A61K47/06A61P15/00A61P29/00
Inventor 马述腾
Owner 马述腾
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