Method for extracting high-purity alpha-linolenic acid by taking flaxseed as raw material

Abstract

The invention discloses a method for extracting high-purity alpha-linolenic acid by taking flaxseed as a raw material and a prepared alpha-ethyl linolenate preparation. The method comprises the following steps: cold-pressing, refining and de-waxing the flaxseed, thereby acquiring flax seed oil; dissolving the flax seed oil in ethyl alcohol for performing esterification reaction, thereby acquiring a mixed fatty acid; cladding urea, slowly cooling, evaporating and concentrating, thereby acquiring mixed unsaturated fatty acid ethyl ester containing over 70% of alpha-ethyl linolenate; performing molecular distillation on the crude product of alpha-ethyl linolenate, thereby acquiring the alpha-ethyl linolenate in purity above 85%; and purifying the alpha-ethyl linolenate in purity above 85% through column chromatography, thereby acquiring the alpha-ethyl linolenate containing more than 95% of alpha-linolenic acid. The method disclosed by the invention has the advantages of simple process, low production cost, excellent separating effect, high purity and suitability for large-scale production. The alpha-ethyl linolenate preparation prepared according to the method disclosed by the invention is high in purity, is stable and reliable, is convenient for large-scale production and use and has high application value.

Description

Technical field: [0001] The invention belongs to the technical field of preparation of linolenic acid, and in particular relates to a method for extracting high-purity alpha-linolenic acid from flax seeds. Background technique: [0002] The main essential fatty acids are omega-3 polyunsaturated fatty acids, which are the core life substances that maintain the evolution of the human brain. In particular, α-linolenic acid, the parent of omega-3 polyunsaturated fatty acids, is an essential fatty acid for the human body, which cannot be synthesized by the human body itself and can only be ingested from the outside world. It is an essential substance for human health, known as "plant brain gold" and "blood nutrient". If the human body lacks omega-3 polyunsaturated fatty acids, it will lead to poor development of gray and white matter in the brain, reduced optic nerve conduction velocity, easy fatigue, and skin allergies and other symptoms. Moreover, a large number of research r...

AI Technical Summary

Problems solved by technology

[0003] At present, the methods for separating and purifying α-linolenic acid from flaxseed in the prior art mainly include: urea inclusion method, silver ion complexation method, column chromatography, molecular distillation method, and β-cyclodextrin inclusion method, such as the invention Patent CN102628003A discloses a method for extracting and purifying α-linolenic acid from linseed oil, which includes the preparation of linseed oil, the preparation of mixed fatty acids in linseed oil, and the separation of α-linolenic acid by β-cyclodextrin inclusion method; the method has High output, low cost, simple and easy to implement, and green and environmentally friendly, but the fatty acid content of the separated α-linolenic acid is only up to 70%.