Oral antibacterial composition containing nisin and polylysine and preparation method thereof
A technology of nisin and polylysine, applied in medical preparations containing active ingredients, oral care, antibacterial drugs, etc., can solve problems such as oral bacterial resistance and health threats, and achieve a bactericidal effect Good, easy to make effect
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Embodiment 1
[0018] Add nisin 0.075% and polylysine 0.05% in the toothpaste to 57.375% deionized water and stir to dissolve, and mix with 16% sorbitol, 14% hydrated silica, 9% glycerin, 2.2% lauryl sulfate Sodium ester, 1.0% flavor, 1.0% cellulose gum, 0.23% sodium pyrophosphate, 0.22% sodium saccharin are mixed, sent to the three-in-one vacuum paste making machine, high-speed stirring and grinding for 30 minutes, vacuum degassing; adding flavor and then stirring and grinding Mix for 15 minutes to obtain a toothpaste paste, which is packaged after aseptic filling.
Embodiment 2
[0020] Add nisine 0.075% and polylysine 0.05% in the mouthwash into 99.025% deionized water and stir to dissolve it, and mix with 0.3% sodium chloride, 0.1% calcium chloride, 0.3% potassium chloride, 0.15% After the disodium hydrogen phosphate is mixed, stir at high speed until all the substances are dissolved, and package after aseptic filling.
Embodiment 3
[0022] Add 76.685% of nisin 0.075%, polylysine 0.05%, pullulan 18.0%, xanthan gum 0.04%, locust bean gum 0.06%, and carrageenan 0.19% in the refreshing tablets. ℃ deionized water; then add 0.4% glycerin, 1.5% total acesulfame potassium and essence, 3% menthol, and stir for 2~3 hours to obtain a glue solution; vacuum bubbles to obtain a film-forming solution; The film liquid is coated on the stainless steel plate with a doctor blade applicator, the thickness of the film is controlled at 20~30μm; steam drying, the drying temperature is 80~90℃, and the film is removed.
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