The invention relates to the technical field of medical apparatus and instruments, in particular to a radio frequency plasma knife electrode vaporization, thermal coagulation and incision operation anti-inflammatory device. The radio frequency plasma knife electrode vaporization, thermal coagulation and incision operation anti-inflammatory device comprises a syringe needle, an insulating layer isconnected to the outer side of the syringe needle in a sleeving mode, a fine needle is movably connected into the insulating layer, and a plastic shell is movably connected to the end, away from the syringe needle, of the insulating layer. All the structures are designed in a spliced mode, thus the preoperative preparation time can be shortened, the preparation process can be simplified, the waiting time of patients can be shortened, meanwhile, corresponding syringe needles can be quickly replaced according to different demands, secondary injuries caused by the fact that syringe needle replacement wastes the time in the operation process are avoided, and using safety of the radio frequency plasma knife electrode vaporization, thermal coagulation and incision operation anti-inflammatory device is improved; and meanwhile, because of the spliced design, parts can be independently replaced when damaged, the problem that the whole device needs to be replaced when a single structure is damaged due to the integrated design is solved, certain cost is saved, and corresponding operation expenses can be reduced to a certain extent.