The present invention discloses a convenient-to-clean disinfection box for medical devices. The convenient-to-clean disinfection box for medical devices comprises a support, a control panel and a doorbolt, a box body is arranged above the support, besides, a stretching rod is arranged at a bottom part of the box body, partition plates are arranged on inner sides of the box body, sliding grooves are formed in two sides of each partition plate, object containing frames are arranged above the partition plates, besides, a handle is arranged on outer sides of the object containing frames, the control panel is arranged on an outer side of the box body, hinges are arranged on a right side of the box body, and besides, a box door is arranged at right sides of the hinges. The convenient-to-clean disinfection box for medical devices is provided with the box body, the box body and a built-in layer are attached to each other, besides, the built-in layer is of a concave structure, and the built-inlayer is arranged inside the box body, so that during disinfection, dust or waste on objects is prevented from falling into the box body, the concave built-in layer is conveniently and rapidly arranged in the box body during use, and when the disinfection box is cleaned, the built-in layer is taken out of the box body to be cleaned, so that an effect of conveniently cleaning the built-in layer isachieved.