The invention relates to the technical field of fruit glass can cleaning, and discloses large-caliber fruit glass can bottle body flushing equipment which comprises a machine body. The bottom of the machine body is fixedly connected with a low-speed motor through a fixing frame, an output shaft of the low-speed motor is fixedly connected with a torque rotating shaft through a coupler, the end, away from the low-speed motor, of the torque rotating shaft penetrates through the bottom of the machine body and is fixedly connected with a rotating table, the bottom of the inner side of the machine body is fixedly connected with an annular sliding groove matched with the outer diameter of the rotating table in size through bolts, the bottom of the rotating table is movably connected with a movable ball, and the bottom of the movable ball is located on the inner side of the annular sliding groove. Through mutual cooperation of the machine body, the low-speed motor, the torque rotating shaft, the rotating table, a positioning supporting barrel, an adjusting positioning mechanism, a vertical circulating mechanism, a transverse positioning mechanism, a rotating motor, a disc type cleaning brush, a spraying head and a control panel, the problems that the labor intensity and cost for cleaning a glass can bottle body are high are solved.