The invention discloses a security and protection monitoring device with a USB power supply type plug-in interface structure. The device comprises a protective cover, a camera, a supporting platform,a mounting plate and a pull rod, the camera is arranged at the upper side in the protective cover, two locating grooves are symmetrically formed in the left and right sides of the bottom of the camera, a fixing block is arranged below the camera, two locating blocks are arranged at positions corresponding to the locating grooves at the top of the fixing block, the locating blocks are inserted in the locating grooves, a fixed baffle is arranged on the left side of the fixing block, baffle screw holes are formed in front and back sides of the fixed baffle, the mounting plate is arranged at the right end of a supporting rod, a first connecting platform is arranged on the left side below the mounting plate, the first connecting platform is rotationally connected with the right end of the supporting rod, the pull rod is arranged at the upper side of the supporting rod, the security and protection monitoring device is simple and reasonable in structure design, and is convenient and quick touse. The device can be connected to a computer, a wireless transmitter, a power source and the like through a USB interface to charge and transmit data to the camera, thereby being more convenient andflexible to use.