39 results about "Intestinal surface" patented technology

The present invention is directed to a particular arabinoxylan (“AX”) preparation and the finding that this preparation has a beneficial effect on the organization of the intestinal microbial community in the lumen and in particular at the site of the gut mucosa, where it modulates the barrier function of the intestinal surface, primarily by modulating the mucosa-associated microbial community towards a relative increase of health beneficial bacteria, such as bifidobacteria and lactobacilli. It is accordingly a first aspect of the present invention to provide said arabinoxylan preparation characterized in comprising isolated water-soluble arabinoxylans and the use thereof to improve functioning (e.g. barrier function) of the intestinal epithelium. Thus, in a further aspect the present invention provides compositions, both pharmaceutical and nutritional compositions, comprising said arabinoxylan preparations; in particular pharmaceuticals, medical foods, food supplements or food compositions, such as infant formula products, dairy products, bakery products or pastry products. The compositions optionally comprise probiotics such as Bifidobacterium or Lactobacillus.

The invention discloses a prescription for treating inflammatory bowel disease and belongs to the field of medicines. The prescription is prepared from lucid ganoderma, salvia miltiorrhiza, tuckahoe, glutamine, threonine, serine and cysteine; the lucid ganoderma, the salvia miltiorrhiza and the tuckahoe have effects of enhancing blood supply and oxygen supply of a human body; the glutamine is used as a main energy source of intestinal mucosa; the threonine, the serine and the cysteine are used as components of mucoprotein. The prescription disclosed by the invention provides nutrition, oxygen and raw materials for generation, renewal and repair of goblet cells and an intestinal surface mucous layer barrier formed by mucoprotein secreted by the goblet cells; the prescription has significant effects for terminating inflammation, repairing intestinal tissues and constructing a normal intestinal surface mucous layer barrier of the human body, and is an effective prescription for treating the inflammatory bowel disease.

The invention discloses an eleventh formula for treating inflammatory bowel disease, and belongs to the field of medicine. The formula comprises the components of salvia miltiorrhiza, threonine, vitamin C, vitamin E, vitamin A and beta-carotene. Salvia miltiorrhiza has the efficacies of enhancing human blood supply and oxygen supply; threonine is a constituent part of mucoproteins; vitamin C, vitamin E, vitamin A and beta-carotene have the effects of blocking and inhibiting the activity of oxygen free radicals, scavenging the oxygen free radicals and protecting human body cells. The formula provides nutrients, oxygen and raw materials for generation, updating and repairing of goblet cells and for goblet cell secreting of the mucoproteins to construct an intestinal surface mucous layer barrier. The formula has obvious effects on terminating inflammation, repairing intestinal tissues and building the human body normal intestinal surface mucus layer barrier, and is an effective formula for treating inflammatory bowel disease.

The invention discloses a composition for treating inflammatory bowel disease, and belongs to the field of drugs. The composition follows principles of reinforcing intestinal tissue cells, building a normal intestinal surface mucous layer barrier, preventing an antigen approaching, touching, adhering to and entering an intestinal wall, and then blocking an abnormal immune response and the occurrence of inflammation. In the composition, ganoderma and radix salviae miltiorrhizae have efficacies of strengthening blood supply and oxygen supply to the human body; glutamine is a main energy source of intestinal mucosa; vitamin C, vitamin E, vitamin A and beta-carotene have functions of inhibiting the activity of oxygen free radicals, scavenging the oxygen free radicals, and protecting human cells. The composition provides nutrition, oxygen and raw materials for generation, renewal and repairing of goblet cells as well as forming of an intestinal surface mucous layer barrier by utilizing mucoprotein secreted by the goblet cells, has obvious effects of building the normal intestinal surface mucous layer barrier for the human body, eliminating inflammation and repairing intestinal tissues, and is used for effectively treating the inflammatory bowel disease.

The invention discloses a composition for treating inflammatory bowel disease, and belongs to the field of drugs. The composition comprises ganoderma, radix salviae miltiorrhizae, threonine, serine, cysteine, vitamin C, vitamin E, vitamin A and beta-carotene, wherein ganoderma and radix salviae miltiorrhizae have efficacies of strengthening blood supply and oxygen supply to the human body; threonine, serine and cysteine are components of mucoprotein; vitamin C, vitamin E, vitamin A and beta-carotene have functions of inhibiting the activity of oxygen free radicals, scavenging the oxygen free radicals, and protecting human cells. The composition provides nutrition, oxygen and raw materials for generation, renewal and repairing of goblet cells as well as forming of an intestinal surface mucous layer barrier by utilizing mucoprotein secreted by the goblet cells, has obvious effects of eliminating inflammation, repairing intestinal tissues and building the normal intestinal surface mucous layer barrier for the human body, and is used for effectively treating the inflammatory bowel disease.

The invention discloses a composition for treating the inflammatory bowel disease, and belongs to the field of medicines. Intestinal epidermal goblet cells are reinforced to construct a normal intestinal surface mucus layer barrier in order to prevent intestinal antigens from approaching, contacting, adhering and entering intestine wall tissues, so abnormal immune response and inflammation generation are blocked out. Salvia miltiorrhiza has the efficacy of enhancing human body blood supply and oxygen supply; threonine is a composition part of mucoproteins, and is an essential amino acid in human bodies; and glutamine is the main energy source of intestinal mucosa. The composition provides nutrition, oxygen and raw materials for generation, updating and restoration of goblet cells and an intestinal tract surface mucus layer barrier composed of mucoproteins secreted by the goblet cells. The composition obtained through combining Salvia miltiorrhiza, ginseng and glutamine has obvious inflammation termination, intestinal tract tissue restoration and human body normal intestinal tract surface mucus layer barrier construction effects, and is an effective formula for treating the inflammatory bowel disease.

The invention discloses a composition for treating inflammatory bowel disease, and belongs to the field of drugs. The composition comprises ginseng, glutamine, threonine, serine, cysteine, vitamin C, vitamin E, vitamin A and beta-carotene, wherein ginseng has efficacies of strengthening blood supply and oxygen supply to the human body; glutamine is a main energy source of intestinal mucosa; threonine, serine and cysteine are components of mucoprotein; vitamin C, vitamin E, vitamin A and beta-carotene have functions of inhibiting the activity of oxygen free radicals, scavenging the oxygen free radicals, and protecting human cells. The composition provides nutrition, oxygen and raw materials for generation, renewal and repairing of goblet cells as well as forming of an intestinal surface mucous layer barrier by utilizing mucoprotein secreted by the goblet cells, has obvious effects of eliminating inflammation, repairing intestinal tissues and building the normal intestinal surface mucous layer barrier for the human body, and is used for effectively treating the inflammatory bowel disease.

The invention discloses a formula for treating inflammatory bowel disease, and belongs to the field of drugs. The formula of the invention follows the principles of reinforcing intestinal epithelial goblet cells, building a normal intestinal surface mucous layer barrier and preventing intestine antigen from approaching, getting into contact with, adhering to and entering an intestinal wall tissue, so as to block abnormal immune response and the happening of inflammation. Radix salviae miltiorrhizae has functions of enhancing blood supply and oxygen supply of a human body; glutamine serves as a main energy source of intestinal mucosa; and threonine, serine and cysteine are main constituent parts of mucoprotein. The formula of the invention can provide nutrition, oxygen and raw materials for the generation, renewal and repair of goblet cells and for the secretion of the mucoprotein from the goblet cells to form an intestinal surface mucous layer barrier. The formula of the invention, as an effective formula for treating inflammatory bowel disease, takes significant effects on terminating inflammation, repairing intestinal structure and building the normal intestinal surface mucous layer barrier of the human body.

The invention discloses a method for isolating primary dendritic cells of the intestinal lamina propria of mice. Including cutting the intestinal tube into 10‑12cm intestinal segments, washing out intestinal surface impurities and intestinal surface mucus, washing the intestinal epithelial cell layer with digestive solution B containing EDTA and EGTA, and then digesting with Liberase TL and DNase I solution C; finally sorted by flow cytometry to obtain the primary dendritic cells of the mouse intestinal lamina propria. The primary dendritic cells isolated by the method of the invention have high purity and complete phenotype characteristics.

The invention discloses a formula for treating inflammatory bowel disease, and belongs to the field of drugs. The formula consists of ginseng, threonine, serine, cysteine, vitamin C, vitamin E, vitamin A and beta-carotene. The ginseng has functions of enhancing blood supply and oxygen supply of a human body; the threonine, the serine and the cysteine are main constituent parts of mucoprotein; and the vitamin C, the vitamin E, the vitamin A and the beta-carotene have functions of depressing the activity of oxygen radical, eliminating the oxygen radical and protecting body cells. The formula of the invention can provide nutrition, oxygen and raw materials for the generation, renewal and repair of goblet cells and for the secretion of the mucoprotein from the goblet cells to form an intestinal surface mucous layer barrier. The formula of the invention, as an effective formula for treating inflammatory bowel disease, takes significant effects on terminating inflammation, repairing intestinal structure and building the normal intestinal surface mucous layer barrier of the human body.

The invention discloses a prescription for treating inflammatory bowel disease and belongs to the field of medicines. The prescription is prepared from lucid ganoderma, salvia miltiorrhiza, tuckahoe, vitamin C, vitamin E, vitamin A and beat-carotene; the lucid ganoderma, the salvia miltiorrhiza and the tuckahoe have effects of enhancing blood supply and oxygen supply of a human body; the vitamin C, the vitamin E, the vitamin A and the beat-carotene have functions of inhibiting the activity of oxygen free radicals, scavenging the oxygen free radicals and protecting human body cells. The prescription disclosed by the invention provides nutrition, oxygen and raw materials for generation, renewal and repair of goblet cells and an intestinal surface mucous layer barrier formed by mucoprotein secreted by the goblet cells; the prescription has significant effects for terminating inflammation, repairing intestinal tissues and constructing a normal intestinal surface mucous layer barrier of the human body, and is an effective prescription for treating the inflammatory bowel disease.

The invention discloses a composition for treating inflammatory bowel disease, and belongs to the field of drugs. The composition comprises ganoderma, poria cocos, glutamine, threonine, serine, cysteine, vitamin C, vitamin E, vitamin A and beta-carotene, wherein ganoderma and poria cocos have efficacies of strengthening blood supply and oxygen supply to the human body; glutamine is a main energy source of intestinal mucosa; threonine, serine and cysteine are components of mucoprotein; vitamin C, vitamin E, vitamin A and beta-carotene have functions of inhibiting the activity of oxygen free radicals, scavenging the oxygen free radicals, and protecting human cells. The composition provides nutrition, oxygen and raw materials for generation, renewal and repairing of goblet cells as well as forming of an intestinal surface mucous layer barrier by utilizing mucoprotein secreted by the goblet cells, has obvious effects of eliminating inflammation, repairing intestinal tissues and building the normal intestinal surface mucous layer barrier for the human body, and is used for effectively treating the inflammatory bowel disease.

The preparation method of an anti-intestinal adhesion double-layer biogel provided by the present invention comprises the following steps: S1: preparing chitosan solution in advance; S2: preparing pure methacrylated chitosan; S3: preparing methyl Acrylated chitosan solution; S4: preparation of pure HA-DA-AEMA; S5: preparation of HA-DA-AEMA solution; S6: curing HA-DA-AEMA solution and methacrylated chitosan solution respectively An inner biogel that adheres to tissues and an outer biogel that resists adhesion. The inner layer of biogel that adheres to the tissue can be tightly combined with the surface of the intestine, which can fix the intestinal wound and prevent inflammatory exudation and bleeding. The anti-adhesion outer layer of biogel can avoid adhesion to the tissue. The viscous surface of the inner biogel adheres to the abdominal cavity or other intestinal tracts, avoiding the pain caused by intestinal adhesions to patients.

The invention discloses a composition for treating inflammatory bowel disease, and belongs to the field of drugs. The composition follows principles of reinforcing intestinal epithelial goblet cells, building a normal intestinal surface mucous layer barrier, preventing an antigen approaching, touching, adhering to and entering an intestinal wall, and then blocking an abnormal immune response and the occurrence of inflammation. In the composition, ganoderma and radix salviae miltiorrhizae have efficacies of strengthening blood supply and oxygen supply to the human body; glutamine is a main energy source of intestinal mucosa. The composition provides nutrition, oxygen and raw materials for generation, renewal and repairing of the goblet cells as well as forming of an intestinal surface mucous layer barrier by utilizing mucoprotein secreted by the goblet cells, has obvious effects of building the normal intestinal surface mucous layer barrier for the human body, eliminating inflammation and repairing intestinal tissues, and is used for effectively treating the inflammatory bowel disease.

The invention discloses a composition for treating inflammatory bowel disease, and belongs to the field of drugs. The composition comprises ganoderma, radix salviae miltiorrhizae, ginseng, threonine, serine and cysteine, wherein ganoderma, radix salviae miltiorrhizae and ginseng have efficacies of strengthening blood supply and oxygen supply to the human body; threonine, serine and cysteine are components of mucoprotein. The composition provides nutrition, oxygen and raw materials for generation, renewal and repairing of goblet cells as well as forming of an intestinal surface mucous layer barrier by utilizing mucoprotein secreted by the goblet cells, has obvious effects of eliminating inflammation, repairing intestinal tissues and building the normal intestinal surface mucous layer barrier for the human body, and is used for effectively treating the inflammatory bowel disease.