The invention relates to a method for controlling energy equipment according to regional population distribution in a building, belonging to the technical field of energy conservation and fire-fighting evacuation of the buildings. In the method disclosed by the invention, a staff access detection device, a human body detection device and a region controller are used. According to the method disclosed by the invention, on one hand, when the human body detection device in a region detects that no people occurs in the region, the number of the people in the region is set to be zero, and on the other hand, by performing region division on the building and estimating the detention time of staff in the region according to the regional functional characteristics, the correction of the deviation of the number of the people in the region can be realized according to the comparison between the region access time of the staff, which is detected by the access detection device, and the detention time of the staff in the region. According to the regional population distribution in the building, which is obtained by the method, electric equipment, fire-fighting evacuation equipment and the like in the region can be controlled through the controller, so that the energy-saving effect of the building and the evacuation efficiency when an emergency occurs are improved and the safety of the staff in the building is ensured.