The invention discloses a composition containing HFC-161 and a stabilizer, wherein the stabilizer is selected from one or more of
epoxy compound, nitro-compound, hindered amines, hindered
phenols, secondary arylamines, beta-diketones, phosphite esters,
salicylic acid esters,
cinnamic acid esters, hydroxybenzophenones, hydroxybenzoic acids, hydroxylphenyl benzotriazoles, hydroxylphenyl triazines, oxanilides, formamidines, polyhydric alcohols, ortho-formates,
organosulfur compounds, olefins,
ethanol amines and fatty amines. The composition provided by the invention is capable of keeping a
stable state in a long time under the coexistence of air or
oxygen, and capable of being used as a
heat transfer composition in the form of a liquid or a gas, a
refrigerant, an
aerosol propellant and the like.