Chinese medicinal composition for treating irritable bowel syndrome and its preparation method

A technology of irritable bowel syndrome and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., and can solve the problems of insignificant clinical efficacy, high price, and no effect of nourishing the kidney.

Active Publication Date: 2007-03-21
GUIZHOU LIANSHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] To sum up, the drug combination in A has the duality of antidiarrheal and regulating constipation, focusing on regulating the pathogenesis, and its clinical application effect is not significant; The irritable syndrome is weak; the prescription in C is to invigorate the spleen and relieve the liver, but has no effect on nourishing the kidney; the prescription in group D is more than invigorating the spleen, but insufficient in nourishing the kidney; the prescription in group E is addictive after long-term use of poppy shell, and ginseng is a great tonic And the price is high, so it should be used with caution, the power of this prescription to invigorate the kidney is weak

Method used

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  • Chinese medicinal composition for treating irritable bowel syndrome and its preparation method

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Effect test

Embodiment 1

[0152] Take gallnut 150g, nutmeg (simmer) 150g, red ginseng 35g, antler cream 45g, ebony plum 150g, myrobalan meat (simmer) 150g, atractylodes 150g, Poria cocos 45g, woody fragrance 150g;

[0153] Among them, crush red ginseng, poria cocos, and antler cream into fine powder; add 10 times the amount of nutmeg, atractylodes, and woody fragrance to soak in water for 2 hours, distill for 5 hours, extract volatile oil, dilute with an equal volume of 95% ethanol, and add to 5 times Add β-cyclodextrin (evenly moistened with appropriate amount of distilled water) to form granules, and dry naturally; soak the dregs after oil extraction with gallnut, ebony, and myrobalan meat with 8 times the amount of water, and decoct Three times, 1 hour each time, filter, concentrate the filtrate to a thick paste with a relative density of 1.35-1.38 (80°C), add fine powder of shamisen such as red ginseng, mix well, dry at 70°C, crush, granulate, and dry , mixed with β-cyclodextrin inclusion granules ...

Embodiment 2

[0155] Take gallnut 115g, nutmeg (simmer) 115g, red ginseng 20g, antler cream 40g, ebony plum 135g, myrobalan meat (simmer) 135g, atractylodes 135g, Poria cocos 40g, woody 135g.

[0156] Its preparation method is with embodiment 1.

Embodiment 3

[0158] Take gallnut 155g, nutmeg (steam) 155g, red ginseng 40g, antler cream 52g, ebony plum 165g, myrobalan meat (steam) 165g, atractylodes 165g, poria cocos 52g, woody fragrance 165g.

[0159] Preparation method is the same as embodiment 1.

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Abstract

The Chinese medicine composition for treating intestinal irritable syndrome is prepared with gallnut, nutmeg, red ginseng, deglued antler powder, dark plum and myrobalan fruit as material and through the technological process including water extraction, extracting volatile oil, inclusion with cyclodextrin, grinding into fine powder and other steps. The pharmacological experiments show that the medicine of the present invention can inhibit the motion of small intestine, resist the sthenic motion of small intestine caused by Neostigmine, resist diarrhea caused by rhubarb, promote the absorption of water inside intestine caused by mannitol, etc. and has relatively high anti-diarrhea effect and high safety.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine compound composition for treating irritable bowel syndrome, that is, a pharmaceutical composition prepared by using Chinese herbal medicine as a raw material, and also relates to a preparation method of the traditional Chinese medicine compound composition. Background technique: [0002] Irritable bowel syndrome (IBS) is a common non-organic intestinal dysfunction disease of the digestive tract, with clinical characteristics of chronic recurrent attacks. The clinical symptoms are abdominal discomfort (abdominal pain, bloating) and abnormal intestinal motility, such as changes in bowel habits (diarrhea or constipation), abnormal stool properties (loose stools, mucus stools, or hard stools), and increased frequency of bowel movements. Existence or intermittent attacks, pathological examination mostly no specific intestinal inflammatory lesions. At present, there is no effective treatment for this ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61K36/285A61K36/284A61K36/258A61K36/185A61K36/076A61K35/64A61K35/32A61P1/14A61P1/00
Inventor 孔繁智
Owner GUIZHOU LIANSHENG PHARMA
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