Composition for resisting fatigue, enhancing immunity and treating rheumatism and preparation method thereof
An immunotherapy and anti-fatigue technology, which can be used in drug combinations, resistance to vector-borne diseases, and medical preparations containing active ingredients, etc. Achieve improved dissolution rate and transfer rate, treatment of rheumatoid arthritis, less irritation and less side effects
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Embodiment 1
[0071] Example 1: Preparation of the composition for anti-fatigue and immunotherapy for rheumatism
[0072] 1.1 Preparation of Cistanche Extract or Cornus Extract
[0073] The Cistanche deserticola or Cornus officinalis decoction pieces are combined with microwave and ultrasonic extraction, vacuum concentration, vacuum freeze-drying, pulverization and sieving to obtain the required Cistanche deserticola or Cornus officinalis extract. The specific process is as follows:
[0074] (a) Combined extraction with microwave and ultrasonic: Put Cistanche or Cornus decoction pieces in a microwave ultrasonic extraction tank, extract 3 times, 0.5h each time, add water 10 times the amount of medicinal materials, keep the microwave power at 8kw, and the ultrasonic power at 2kw, The extraction temperature was kept at 90°C, filtered, and the extracts were combined;
[0075] (b) vacuum concentration: the above-mentioned extraction solution is concentrated under vacuum, the concentration temp...
experiment example 2
[0114] Experimental Example 2: Evaluation of Functional Tests of Animals to Enhance Immunity
[0115] 2.1 Materials
[0116] The test sample is the composition for anti-fatigue and immunotherapy of rheumatism of the present invention prepared in Example 1.6. The recommended daily dose of the product is 5g, and the recommended dose of the sample is 0.083g / kg.BW based on an adult body weight of 60kg.
[0117] The experiment set up three dose groups and a negative control group (distilled water). The low, medium and high doses were 0.42, 0.83 and 2.50 g / kg of the anti-fatigue and immunotherapy composition for rheumatism, which was equivalent to 5, 10 of the recommended human dose. and 30 times. Before the test, the samples were prepared into various doses with distilled water as the solvent, and mixed well for the test.
[0118] In the three-dose groups, 4.2, 8.3, and 25.0 g of the product fine powder were added to 100 mL of distilled water to prepare samples with concentration...
experiment example 3
[0140] Experimental Example 3: Evaluation of Functional Tests for Relieving Physical Fatigue in Animals
[0141] 3.1 Materials
[0142] The test sample is the anti-fatigue and immune-enhancing rheumatism composition of the present invention trial-produced in Example 1.6. The recommended daily dose of the product is 5g. Based on an adult body weight of 60kg, the recommended sample dose is 0.083g / kg.BW.
[0143] The experiment set up three dose groups and a negative control group (distilled water). The low, medium and high doses were 0.42, 0.83 and 2.50 g / kg of the anti-fatigue and immunotherapy composition for rheumatism, which was equivalent to 5, 10 of the recommended human dose. and 30 times. Before the test, the samples were prepared into various doses with distilled water as the solvent, and mixed well for the test.
[0144] In the three-dose groups, 4.2, 8.3, and 25.0 g of product fine powder were added to 100 mL of distilled water to prepare samples with concentrations...
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