Medical coating applied to implanted medical instrument and preparation method of medical coating

Abstract

The invention discloses a medical coating applied to an implanted medical instrument. The coating comprises a titanium-yttrium coating, a titanium nitride-yttrium alloy layer, a tantalum-yttrium coating and a tantalum-zinc-silver coating; the titanium-yttrium coating coats the outer layer of a base material of an implanted medical instrument; the titanium nitride-yttrium alloy layer coats the outer layer of the titanium-yttrium coating; the tantalum-yttrium coating coats the outer layer of the titanium nitride-yttrium alloy layer; and the tantalum-zinc-silver coating coats the outer layer of the tantalum-yttrium coating, wherein the tantalum-zinc-silver coating can be converted to a tantalum-magnesium-silver coating. The silver element of the medical coating can effectively inhibit generation of bacterial biofilms and inflammation, the zinc element and the magnesium element can effectively promote healing of wounds and growth of bone tissues, the yttrium element and the tantalum element can effectively improve fatigue resistance of a metal material, and the tantalum element can effectively enhance development performance of an X-ray machine. Harmful metal ions are embedded, so thatthe corrosion-resistant potential is improved, the biocompatibility is improved, electromagnetism of the metal implant is shielded, and CT diagnosis is realized.

Description

technical field [0001] The invention relates to a medical coating, in particular to a medical coating applied to implanted medical devices and a preparation method thereof. Background technique [0002] With the improvement of my country's overall economic development level, the increase in medical and health needs, and the guidance of national policies, the domestic implantable medical device market continues to expand, showing huge development potential. According to the definition in the "Medical Device Classification Rules", an implanted medical device refers to: any surgical operation, all or part of which enters the human body or natural orifice; stays in the body for a long time after the operation, or part of these devices stays in the body For at least 30 days, these devices are considered implanted devices. For example: coronary stents, peripheral vascular stents, prostate stents, bone nails and plates, artificial joints, occluders, cardiac pacemakers, etc. Impla...

AI Technical Summary

Problems solved by technology

Vanadate and vanadium cations accumulate in the liver, kidney, bone, spleen and other organs in the human body, and their toxic effects are related to the metabolism of phosphate. They act through the ATPase that affects potassium, sodium, hydrogen and calcium ions, and their toxicity may exceed Chromium and nickel, cause cancer

[0007] Nickel element Ni is one of the main components of medical nickel-titanium memory alloy materials. Excessive Ni ions are cytotoxic, can cause local tissue irritation or tissue necrosis, and even cause respiratory dysfunction and allergic reactions. Ni ions can also inhibit cell Proliferate, potentially carcinogenic

Studies have shown that after divalent nickel ions enter cells in the human body, they bind to ligands in the cytoplasm and will not accumulate in the nucleus, so they will not cause cancer, but nickel compounds may cause cancer

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