Composition with anti-alcohol and liver-protection effects, and preparation method of composition

A technology for detoxifying and protecting the liver and a composition is applied in the field of a composition having the effect of detoxifying and protecting the liver and the field of preparation thereof, which can solve the problems of high price, low efficiency of detoxification, strong liver toxicity and side effects, etc. Surface area, effect of prolonging intoxication latency

Pending Publication Date: 2020-01-10
GUANGDONG OCEAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the defects and deficiencies of the existing hangover products, such as low hangover efficiency, strong toxic and side effects on the liver, and high price, and provide a composition with the effects of hangover and liver protection and its preparation method

Method used

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  • Composition with anti-alcohol and liver-protection effects, and preparation method of composition
  • Composition with anti-alcohol and liver-protection effects, and preparation method of composition
  • Composition with anti-alcohol and liver-protection effects, and preparation method of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Example 1: Preparation of a composition having anti-alcoholic and liver-protecting effects

[0053] A composition with anti-alcoholic and liver-protecting effects, comprising the following components in parts by weight: 30 parts of tilapia skin polypeptides, 15 parts of saponin, 15 parts of mulberry concentrate, carboxymethyl chitosan 10 servings of balls.

[0054] The preparation method of the composition with anti-alcoholic and liver-protecting effects is as follows: according to the weight parts, take the tilapia skin polypeptide, saponin, and mulberry concentrated solution and dissolve them in water, stir them evenly, and drip them at a speed of 0.5 mL / s was dropped into the carboxymethyl chitosan microsphere solution and reacted for 10 minutes to obtain the composition, which was named M1;

[0055] Wherein, the preparation method of the tilapia skin polypeptide is: using tilapia skin as a raw material, after mixed hydrolysis with papain with a mass concentration o...

Embodiment 2

[0058] Example 2 Preparation of a composition having anti-alcoholic and liver-protecting effects

[0059] A composition with anti-alcoholic and liver-protecting effects, comprising the following components in parts by weight: 20 parts of tilapia skin polypeptides, 20 parts of saponin, 20 parts of mulberry concentrate, carboxymethyl chitosan Serves 5 balls.

[0060] The preparation method of the composition with anti-alcoholic and liver-protecting effects is as follows: according to the weight parts, take tilapia skin polypeptide, saponin, and mulberry concentrated solution and dissolve them in ethanol, stir them evenly, and then drip them at a speed of 0.1mL / s was dropped into the carboxymethyl chitosan microsphere solution and reacted for 5min to obtain the composition, named as M2;

[0061] Wherein, the preparation method of the tilapia skin polypeptide is: using tilapia skin as a raw material, after mixed hydrolysis with papain with a mass concentration of 0.2% and neutral...

Embodiment 3

[0063] Example 3: Preparation of a composition having anti-alcoholic and liver-protecting effects

[0064] A composition with anti-alcoholic and liver-protecting effects, comprising the following components in parts by weight: 40 parts of tilapia skin polypeptides, 10 parts of saponin, 10 parts of mulberry concentrate, carboxymethyl chitosan 15 servings of balls.

[0065] The preparation method of the composition with anti-alcoholic and liver-protecting effects is as follows: according to the weight parts, take tilapia skin polypeptide, saponin, and mulberry concentrated solution, dissolve them in isopropanol, stir them evenly, and drop them into carboxylated React in the methyl chitosan microsphere solution for 15 minutes to obtain the composition, which is named as M3.

[0066] Wherein, the preparation method of the tilapia skin polypeptide is: using tilapia skin as a raw material, after mixed hydrolysis with papain with a mass concentration of 0.08% and neutral protease wi...

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Abstract

The invention discloses a composition with anti-alcohol and liver-protection effects, and a preparation method of the composition. The composition with the anti-alcohol and liver-protection effects comprises, by weight, 20-40 parts of tilapia skin polypeptides, 10-20 parts of sarmentosin, 10-20 parts of a mulberry concentrated solution, and 5-15 parts of carboxymethyl chitosan microspheres. All the components in the composition work jointly and compatibly so that the anti-alcohol and liver-protection effects can be achieved rapidly and synergistically. The invention further provides a productwith the anti-alcohol and liver-protection effects on the basis of the composition. By adopting the composition with the anti-alcohol and liver-protection effects, the drunkenness rate of a mouse suffering from acute alcohol intoxication can be significantly reduced, sleep maintenance time and sober-up time of the mouse are shortened, and a drunkenness latent period of the mouse is prolonged; andmeanwhile, abnormal increases of levels of alanine aminotransferase, alkaline phosphatase and aspartate aminotransferase in mouse serum are inhibited, the significant liver protection effect is shown,and therefore the composition has wide application value in preparing anti-alcohol and liver-protection products.

Description

technical field [0001] The invention belongs to the technical field of health care products. More specifically, it relates to a composition with anti-alcoholic and liver-protecting effects and a preparation method thereof. Background technique [0002] China has a long history of drinking culture. It is a big wine-making country in the world, and it is also one of the important wine-consuming countries. Moderate drinking has the effects of invigorating blood circulation, dredging collaterals, dispelling cold, and promoting metabolism, which is beneficial to health; while excessive drinking can easily cause damage to tissues and organs such as liver, kidney, and intestines and stomach. Threat to human health. Acute heavy drinking can cause acute alcohol poisoning, which not only brings dizziness, nausea, restlessness, coma, incontinence and other uncomfortable symptoms to patients, but also causes respiratory depression, brain cell death, stroke and hemiplegia in severe cas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A61P1/16A61P39/02A23L33/18A23L33/105A23L33/125A23P10/20A61K31/7028A61K31/722
CPCA61K38/012A61K31/7028A61K36/605A61K31/722A61P1/16A61P39/02A23L33/18A23L33/105A23L33/125A23P10/20A23V2002/00A61K2300/00A23V2200/334A23V2250/21A23V2250/55A23V2250/511
Inventor 孔松芝胡章李思东卢思彤李东东廖铭能郭家棋王冶
Owner GUANGDONG OCEAN UNIVERSITY
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