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Compound for treating HPV infection and application thereof

A composition and extract technology, applied in the field of medicine, can solve the problems of short onset time, low recurrence rate, large side effects and the like, and achieve the effects of no toxic side effects, short onset time and low recurrence rate

Inactive Publication Date: 2017-06-13
BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to solve the defects of inconvenient operation, large side effects and high price of the HPV treatment method, the present invention especially proposes a composition for treating HPV infection, which can be used for treating HPV infection and diseases related to HPV infection, such as cervical cancer and genital warts and other diseases, providing HPV infection patients with HPV infection drugs with good curative effect, short onset time, no dependence, no side effects, and low recurrence rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Embodiment 1: A preparation method of mussel soft tissue extract.

[0051] Shell the mussels, collect 300g of soft tissue, divide it into three parts, add 100ml of the acidic solution in the table below with a content of 0.3%, homogenate for 10 minutes, and centrifuge to obtain the supernatant, which is the mussel soft tissue extract.

[0052] The protein content and pH value in the supernatant were determined, and the protein content was determined by the Coomassie brilliant blue method.

[0053] Table 1

[0054] example acid solution protein content pH value 1 citric acid 2.6mg / ml 4.5 2 Acetic acid 3.5mg / ml 3.2 3 perchloric acid 3.0mg / ml 1.0

Embodiment 2

[0055] Example 2: A composition comprising mussel soft tissue extract, trypsin and oleic acid

[0056] The composition for treating HPV infection comprising mussel soft tissue extract, trypsin and oleic acid consists of the following components: mussel soft tissue extract dry powder 15mg, trypsin dry powder 20mg, oleic acid 10ml is added to purified water and fully dissolved to treat HPV Oral solution for infections.

[0057] Collect 30 cases of female patients with HPV infection, without clinical symptoms, infected with high-risk HPV virus (including types 16, 18, 31, 33, 35, 39, 45, 51, etc.) test group and control group. The test group took the composition for treating HPV infection prepared in Example 2, once a day, 15ml each time, with an interval of 24 hours. During the period of medication, sexual life and bathing were prohibited, and the menstrual period was suspended. It was used continuously for 2 weeks. The control group did not use any treatment measures. All pa...

Embodiment 3

[0059] Example 3: A composition comprising mussel soft tissue extract, trypsin and linoleic acid

[0060] The composition for treating HPV infection comprising mussel soft tissue extract, trypsin and linoleic acid consists of the following components: mussel soft tissue extract dry powder 10mg, trypsin dry powder 15mg, linoleic acid 5ml, mussel soft tissue extract and Sieve trypsin, mix compressible starch, microcrystalline cellulose, and sodium carboxymethyl cellulose, granulate with 5% hypromellose aqueous solution, and dry at 60°C. Base cellulose, micropowder silica gel, trypsin, mussel soft tissue extract, linoleic acid are mixed evenly and then mixed with granules, and then packed into granules.

[0061] Collect 30 patients with cervical HPV infection, aged between 20-50, the course of disease is 3-21 months. The diagnostic criteria for cervical HPV infection are as follows: the exfoliated cells of the cervix are collected, and the RLU / Co≥1.0 of the test sample is diagno...

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PUM

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Abstract

The invention belongs to the medical field, and in particular relates to a composition for treating HPV infection and application thereof. The composition comprises mussel soft tissue extract, trypsin and oleic and / or linoleic acid and / or oils enriched therefor. The composition of the present invention can be used to treat HPV infection and diseases related to HPV infection, such as cervical cancer and genital warts, and provide patients with HPV infection with good curative effect, short onset time, no dependence, no side effects, and low recurrence rate. Low HPV infection medication.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a composition for treating HPV infection and application thereof. Background technique [0002] Human papillomavirus (HPV) belongs to the Papillomavirus genus of the family Papillomaviridae, and is a spherical non-enveloped small double-stranded circular DNA virus. More than 200 types of HPV have been found so far, and HPV can be divided into high-risk and low-risk types according to whether they cause cancer. The current relatively unified epidemiological classification defines 15 high-risk HPV types (such as HPV-16, HPV-18) and 12 low-risk HPV types (such as HPV-6, HPV-11). The pathogenic mechanism of HPV is that HPV has a high affinity for skin and mucosal epithelial cells. After infecting host skin or mucosal epithelial cells, it can self-replicate in the nucleus or integrate into the host cell DNA, and replicate synchronously with the host cell. and transcribed. Viral ...

Claims

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Application Information

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IPC IPC(8): A61K38/48A61P31/20A61P35/00A61P17/12A61K35/618A61K31/201A61K36/482A61K36/489
CPCA61K38/48A61K31/201A61K35/618A61K36/482A61K36/489C12Y304/21004
Inventor 王小磊
Owner BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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