A preparation method of medical pure magnesium surface coupling loaded bone growth-inducing traditional Chinese medicine coating

A technology for bone growth and traditional Chinese medicine, applied in the field of preparation of medical pure magnesium surface coating, can solve the problems of hemolysis, inflammation, hindering clinical application, tissue growth and repair hazards, etc., and achieves improved biological activity, excellent biocompatibility, Improved effect of poor corrosion resistance

Inactive Publication Date: 2018-06-26
JIAMUSI UNIVERSITY
View PDF11 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, magnesium-based biomedical materials degrade too quickly in the physiological environment, which will cause a series of biological problems such as hemolysis and inflammation, and cause potential harm to tissue growth and repair, hindering their wider clinical application.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A preparation method of medical pure magnesium surface coupling loaded bone growth-inducing traditional Chinese medicine coating
  • A preparation method of medical pure magnesium surface coupling loaded bone growth-inducing traditional Chinese medicine coating
  • A preparation method of medical pure magnesium surface coupling loaded bone growth-inducing traditional Chinese medicine coating

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0040] Specific embodiment 1: This embodiment is a preparation method of a medical pure magnesium surface-coupled bone growth-inducing traditional Chinese medicine coating, which is specifically carried out according to the following steps:

[0041] 1. Pretreatment of the surface of the pure magnesium sample: use sandpaper to roughly grind the surface of the pure magnesium sample to be treated, then use acetone and distilled water to sonicate each for 25 minutes, dry it, put it in a sealed bag and seal it for later use;

[0042] 2. Configure the micro-arc oxidation electrolyte: put distilled water into the beaker, then add sodium silicate, potassium hydroxide, potassium fluoride and disodium ethylenediaminetetraacetate in sequence, and stir well after each reagent is added Then add the next reagent, after adding all the reagents, perform ultrasonic oscillation until all the reagents are completely dissolved to obtain the micro-arc oxidation electrolyte; the concentration of sod...

specific Embodiment approach 2

[0048] Specific embodiment two: the difference between this embodiment and specific embodiment one is: the concentration of sodium silicate in the micro-arc oxidation electrolyte described in step 2 is 15g / L, and the concentration of potassium hydroxide is 10g / L, The concentration of potassium fluoride is 8 g / L, and the concentration of disodium edetate is 1 g / L. Others are the same as the first embodiment.

specific Embodiment approach 3

[0049] Embodiment 3: The difference between this embodiment and Embodiment 1 is that the silane coupling agent described in Step 4 ② is the silane coupling agent KH-550. Others are the same as the first embodiment.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
Login to view more

Abstract

A preparation method of medical pure magnesium surface coupling load inducing bone growth traditional Chinese medicine coating relates to a preparation method of medical pure magnesium surface coating. According to the preparation method provided by the invention, a series of biological problems, such as hemolysis, inflammation and the like, caused by the fact that the existing medical magnesium and magnesium alloy materials are degraded quickly in the physiological environment, and the technical problems that potential hazard is generated on tissue growth and repair are solved. The preparation method comprises the steps: 1, performing surface pretreatment on a pure magnesium test sample; 2, preparing micro-arc oxidation electrolyte; 3, performing ultrasonic micro-arc oxidation treatment; and 4, performing aftertreatment. The coating composite material prepared by the method is formed by compounding pure magnesium and coupling modifying self-assembling traditional Chinese medicine coating on the surface of the pure magnesium, and has the characteristics of metal materials and ceramic materials; an ultrasonic-micro-arc oxidation composition technology and a self-assembling technology of the preparation method are green environmentally-friendly processes, so low production cost can be guaranteed well; furthermore, the prepared material has excellent bone inducing property, corrosion resistance and antibacterial property.

Description

technical field [0001] The invention relates to a preparation method of a medical pure magnesium surface coating. Background technique [0002] In the 21st century, biodegradable medical magnesium and magnesium alloy materials have become an important new research direction for biomedical metals. Degradable medical magnesium and magnesium alloys have an elastic modulus close to that of human bone, and their density is also close to that of human bone. They have appropriate strength, good biocompatibility, and mechanical properties similar to natural bone. These properties make magnesium and its alloys likely to be ideal orthopedic implant materials. However, magnesium-based biomedical materials degrade too quickly in the physiological environment, which will cause a series of biological problems such as hemolysis and inflammation, and cause potential harm to tissue growth and repair, hindering their wider clinical application. Now scholars are mainly concerned with control...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): C25D11/30A61L27/04A61L27/28A61L27/54
CPCA61L27/047A61L27/28A61L27/54A61L2300/30A61L2300/404A61L2300/412A61L2300/606A61L2400/18C25D11/026C25D11/30
Inventor 李慕勤王晶彦张德秋彭书浩
Owner JIAMUSI UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap