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Traditional Chinese medicine composition for treating hyperthyroidism and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of pharmacy, can solve the problems of radiotherapy safety hazards, induction of thyroid nodules, cancer and genetic complications, and achieve the effects of improving immunity, regulating endocrine, and having no toxic and side effects

Inactive Publication Date: 2014-12-03
赵亮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the deep part of the thyroid gland contains four very small parathyroid glands that regulate calcium and phosphorus metabolism, if the surgical experience is insufficient and the parathyroid glands are accidentally removed, it will cause lifelong tetany due to low calcium. In addition, it may also damage the vagus nerve cause hoarseness
2. Radioactive iodine treatment: Radioactive iodine is made by marking iodine and radioactive substances, also known as 131 iodine. The use of 131 iodine to treat hyperthyroidism has a history of more than half a century. Since 1942, this method has been used to treat hyperthyroidism. Since the first patient with hyperthyroidism, the number of hyperthyroid patients who have received 131 iodine treatment in the world has reached 2 million. Up to now, more than 200,000 hyperthyroid patients have received 131 iodine treatment in China; however, radiotherapy has certain safety hazards and has been Controversy that radioactive iodine therapy may induce thyroid nodules, carcinoma, and genetic complications creates a psychological burden on many patients
3. Drug treatment: The condition can be controlled by taking drugs orally, but it needs to be taken for a long time, and the drug cannot be stopped without authorization. The recurrence rate of stopping the drug is about 30% to 50%.
And some patients with severe liver disease cannot use this kind of treatment for hyperthyroidism
For patients taking oral drugs, they must go to the hospital to check blood and liver function in one to two weeks, which is very troublesome

Method used

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Effect test

preparation example Construction

[0046] Wherein, when the dosage form of the Chinese medicine composition is a tablet, its preparation method comprises the following steps:

[0047] In the first step, mix halogen alkali, kelp, vulture, scrophulariaceae, pinellia chinensis, xanthogonia and Tibetan antelope horn, add alcohol concentration of 80% to 90% of alcohol concentration 6 to 10 times the mass of the mixture, and reflux extraction 3 ~5 times, each time for 3~6 hours, filter, combine the filtrates of each time, recover ethanol, concentrate to a paste with a relative density of 1.32~1.36 at 65°C, and set aside;

[0048] The second step is to mix the remaining raw medicinal materials in proportion, add 3 to 6 times the amount of water relative to the mass of the mixture, boil for 2 to 5 hours, filter, concentrate to a paste with a relative density of 1.35 to 1.38 at 65°C, and set aside;

[0049] The third step is to mix the paste obtained in the first step and the second step, and dry it under reduced pressu...

Embodiment 1

[0059] Embodiment 1 tablet of the present invention

[0060] Take 250g of sea panche, 300g of goose sausage, 200g of Muhe, 250g of mozuku, 200g of laurel, 280g of japonica, 300g of Hemerocallis, 150g of wet sage, 220g of Suogudan, 200g of sharp tongue moss, 80g alkali, 300g kelp, 100g vulture, 150g scrophulariae, 160g Qingpinellia, 300g xanthophyll and 150g Tibetan antelope horn;

[0061] Its preparation method comprises the following steps:

[0062] In the first step, mix halogen alkali, kelp, vulture, scrophulariaceae, pinellia chinensis, xanthogonia and Tibetan antelope horn, add alcohol concentration 8 times the mass of the mixture and extract with 90% ethanol for reflux extraction 4 times, each time 5 hours, filter, and combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.36 at 65°C, and set aside;

[0063] In the second step, mix the remaining raw medicinal materials in proportion, add water 4 times the mass of the mixture, boil f...

Embodiment 2

[0067] Embodiment 2 capsules of the present invention

[0068] Take 180g of sea panche, 250g of goose sausage, 150g of Muhe, 230g of mozuku, 180g of laurel, 250g of japonica, 250g of Hemerocallis, 180g of wet sage, 150g of Suogudan, 220g of sharp tongue moss, 60g alkali, 250g kelp, 80g vulture, 120g scrophulariae, 120g Qingpinellia, 250g xanthophyll and 100g Tibetan antelope horn;

[0069] Its preparation method comprises the following steps:

[0070] In the first step, mix kelp, vulture, scrophulariaceae, pinellia chinensis, xanthogonia and Tibetan antelope horn according to the stated ratio, add 7 times of water to the mixture to extract the volatile oil, and clathrate the obtained volatile oil with β-cyclodextrin , the ratio of volatile oil to β-cyclodextrin is 1:6, stirred for 180 minutes at a temperature of 75°C to obtain a volatile oil clathrate, and set aside; in addition, the water extract is concentrated to a clear paste with a relative density of 1.35 at 75°C;

[0...

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating hyperthyroidism and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials: asteroid, stellaria aquatica, fingerleaf rodgersflower rhizome, nemacystus, caulis et folium plucheae, ishige okamurae, scytosiphon lomentaria, gnaphalium, rodgersia aesculifolia, rhynchoglossum obliquum, brine alkali, kelp, cinereous vulture, radix scrophulariae, rhizoma pinelliae preparata, airpotato yam and Tibetan antelope horn. The traditional Chinese medicine composition has the beneficial effects that the used traditional Chinese medicines have the efficacies of softening hard lumps, dispelling nodes, promoting blood circulation to remove blood stasis, soothing the liver, dispelling melancholy, and regulating qi-flowing for eliminating phlegm on the basis of the traditional theory of traditional Chinese medicine science in China, internal secretion can be regulated, the immunity is improved, and the normal function of thyroid is restored. The traditional Chinese medicine composition has the advantages of quick acting for hyperthyroidism treatment, accurate curative effect, high safety, no toxic or side effect and can avoid recurrence of hyperthyroidism.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine composition for treating hyperthyroidism and a preparation method thereof. Background technique [0002] Hyperthyroidism is the abbreviation of hyperthyroidism, which is a group of common endocrine diseases caused by excessive secretion of thyroid hormone caused by various reasons. The main clinical manifestations are polyphagia, weight loss, fear of heat, hyperhidrosis, palpitations, agitation and other hypermetabolic syndromes, increased nerve and blood vessel excitement, and varying degrees of goiter, exophthalmos, hand tremors, and tibial vascular murmurs. In severe cases, hyperthyroid crisis, coma and even life-threatening may occur. [0003] The treatment of hyperthyroidism mainly includes surgical treatment, radioactive iodine treatment and western medicine drug treatment. 1. Surgical treatment: most of the thyroid is removed, and the radi...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P5/16A61K35/56A61K35/32A61K35/12A61K33/14
Inventor 赵亮
Owner 赵亮
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