Submerged fermentation culturing method for medicinal hericium erinaceus mycelium liquid

Abstract

The invention discloses a submerged fermentation culturing method for a medicinal hericium erinaceus mycelium liquid; compared with a common edible hericium erinaceus, the obtained hericium erinaceus mycelium contains five cancer-fighting substances, seven vitamins, three active cellulases, 18 amino acids, trace elements essential to the human body and on the like except for polysaccharide and polypeptide, wherein contents of cystine, histidine and arginine with larger medicinal values are large; and the 6-7 amino acid identifying points and the protein content (16.65%) of the obtained hericium erinaceus mycelium are respectively 3 times and 1.8 times larger than those of other hericium erinaceus. Infrared spectrum also proves that the hericium erinaceus mycelium also contains a special cancer-fighting organic acid, which is not available in the common hericium erinaceus, except for a hydroxyl ammonia compound. Compared with the traditional manual solid culturing method, the submerged fermentation culturing method disclosed by the invention has the advantages as follows: the breakthrough from manual culture of the hericium erinaceus mycelium to standard and industrial production of the hericium erinaceus mycelium is achieved, the production period is reduced from the 52 days of the traditional culturing method to 14 days, energy is saved and consumption is reduced by 30%, and production cost is reduced by 70%.

Description

technical field [0001] The invention relates to the technical field of microorganism cultivation, in particular to a method for cultivating medicinal Hericium erinaceus mycelium. Background technique [0002] Hericium erinaceus is named because its fruiting body resembles the head of a little monkey. It is a rare edible fungus with both edible and medicinal value. It is flat in nature and sweet in taste. Cancer, treatment of neurasthenia, for the treatment of digestive system diseases and tumors such as indigestion, gastric ulcer, esophageal cancer, gastric cancer, duodenal cancer, and spout cancer. At present, Hericium erinaceus has been successfully used in existing products, such as the marketed Hericium Jianweiling Capsules, in which Hericium erinaceus is the main ingredient of the product. [0003] At present, there are mainly three kinds of production approaches of Hericium erinaceus: 1. Artificial cultivation, the advantage is that it is simple and easy to implement,...

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Problems solved by technology

[0003] At present, there are mainly three kinds of production approaches of Hericium erinaceus: 1. Artificial cultivation, the advantage is that it is simple and easy to implement, and the cost is low; the disadvantage is that the cultivation period is long, about 3 months; 2, solid fermentation, cultivate Hericium erinaceus bacteria with solid medium Silk, to obtain secondary metabolites, its advantages are: the medium is simple and widely sourced, and the price is cheap; the fermentation process generally does not require strict aseptic operation; the oxygen supply and temperature during the cultivation process can be controlled by direct air forced ventilation; The treatment of fermentation residue is simple, and it can be directly used as feed or fertilizer; the disadvantages are: the water activity of the medium is low, the medium is uneven and difficult to stir, the growth of bacteria, the absorption of nutrients and the secretion of metabolites are uneven, making The monitoring and control of fermentation parameters is difficult, so continuous operation and automation are difficult; the temperature control of the heat generated by microbial respiration and metabolism is very difficult; the use of solid-state culture is mostly based on empirical data and operating experience, and it is easy to contaminate miscellaneous bacteria; 3. Liquid deep layer Fermentation to obtain the best operating conditions to produce a large amount of mycelium and metabolites in a relatively short period of time. The advantages are: industrial continuous production can be carried out, and the source of raw materials for cultivation is wide. The best cultivation conditions can be obtained by controlling the fermentation device to obtain cycle Short and high efficiency; the disadvantage is that the cycle is still long, and the production of mycelium is low, it is difficult to form a large-scale application

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